Substanzen

Righting a historical wrong: The UN review of the international status of the coca leaf

15. Dezember 2024 | Kokain

Righting a historical wrong: The UN review of the international status of the coca leaf In July 2023, the World Health Organization (WHO) received a formal notification by the Plurinational State of Bolivia requesting the Expert Committee on Drug...

Golf von Mexiko Forscher finden Fentanyl in Delfinen

15. Dezember 2024 | Fentanyl

Golf von Mexiko Forscher finden Fentanyl in Delfinen Die Substanz wirkt etwa 100-mal stärker als Morphium und wird als Droge missbraucht: Nun hat ein Forschungsteam Fentanyl und weitere Arzneien in Delfinen nachgewiesen. Die Ergebnisse deut...

Freizeitkonsum von Distickstoffmonoxid in Europa: Situation, Risiken, Reaktionen

11. Dezember 2024 | Verschiedene

Freizeitkonsum von Distickstoffmonoxid in Europa: Situation, Risiken, Reaktionen In einigen Ländern Europas ist in letzter Zeit ein Anstieg des Freizeitkonsums von Distickstoffmonoxid zu beobachten. Diese Seite bietet eine Zusammenfassung der akt...

USA DEA – Drug Enforcement Administration: Factsheets über psycho-aktive Substanzen

11. Dezember 2024 | Verschiedene

USA DEA – Drug Enforcement Administration: Factsheets über psycho-aktive Substanzen https://www.dea.gov/factsheets

GLP-1s Hold Promise for Addiction but Questions Remain

11. Dezember 2024 | Verschiedene

GLP-1s Hold Promise for Addiction but Questions Remain Medscape - December 05, 2024. https://www.medscape.com/viewarticle/glp-1s-hold-promise-addiction-questions-remain-2024a1000mfj

Integration of pharmacochemistry, pharmacodynamics and metabolomics to reveal active ingredients and mechanism of Nan Bao detox capsule alleviating methamphetamine addiction.

10. Dezember 2024 | Amphetamine

Integration of pharmacochemistry, pharmacodynamics and metabolomics to reveal active ingredients and mechanism of Nan Bao detox capsule alleviating methamphetamine addiction. Zhang B, Yang C, Zheng Y, Li X, Wang X, Yuehui L. Addict B...

MDMA-assisted psychotherapy for the treatment of PTSD: A systematic review and meta-analysis of randomized controlled trials (RCTs).

10. Dezember 2024 | Amphetamine

MDMA-assisted psychotherapy for the treatment of PTSD: A systematic review and meta-analysis of randomized controlled trials (RCTs). Shahrour G, Sohail K, Elrais S, Khan MH, Javeid J, Samdani K, Mansoor H, Hussain SI, Sharma D, Ehsan M, Nas...

Pregabalin dependence - A rising concern.

10. Dezember 2024 | Gabapentinoide

Pregabalin dependence - A rising concern. Rani S, Bhatia MS. Ind Psychiatry J. 2024 Aug;33(Suppl 1):S299-S300. doi: 10.4103/ipj.ipj_179_23. Epub 2024 Feb 16. PMID: 39534175; PMCID: PMC11553582. https://pmc.ncbi.nlm.nih.gov/articles/...

'I haven't discussed anything with anyone': lived experience of long-term users of benzodiazepine receptor agonists regarding their treatment for substance use disorder.

10. Dezember 2024 | Benzodiazepine

'I haven't discussed anything with anyone': lived experience of long-term users of benzodiazepine receptor agonists regarding their treatment for substance use disorder. Van Ngoc P, Ceuterick M, Belche JL, Scholtes B. Int J Qual Stud Healt...

Captagon: A comprehensive bibliometric analysis (1962-2024) of its global impact, health and mortality risks.

10. Dezember 2024 | Verschiedene

Captagon: A comprehensive bibliometric analysis (1962-2024) of its global impact, health and mortality risks. Fong S, Carollo A, Rossato A, Prevete E, Esposito G, Corazza O. Saudi Pharm J. 2024 Nov;32(11):102188. doi: 10.1016/j.jsps....

Methylphenidate abuse and misuse in patients affected with a psychiatric disorder and a substance use disorder: a systematic review.

10. Dezember 2024 | Verschiedene

Methylphenidate abuse and misuse in patients affected with a psychiatric disorder and a substance use disorder: a systematic review. Chiappini S, Gramuglia PD, Mosca A, Cavallotto C, Miuli A, Corkery JM, Guirguis A, Schifano F, Martinotti G...

Gabapentin and pregabalin exposures reported to United States poison centers, 2012-2022.

10. Dezember 2024 | Gabapentinoide

Gabapentin and pregabalin exposures reported to United States poison centers, 2012-2022. Carter EJR, Rine NI, Kistamgari S, Hays HL, Spiller HA, Yang J, Zhu M, Smith GA. Inj Epidemiol. 2024 Nov 1;11(1):59. doi: 10.1186/s40621-024-005...

“Even worse than fentanyls”: nitazenes in the USA

10. Dezember 2024 | Opioide

“Even worse than fentanyls”: nitazenes in the USA Samarasekera, Udani The Lancet, Volume 404, Issue 10469, 2250 - 2251 Registrierung erforderlich https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02663-1/abstracthttps://www.th...

Exogenous Opioids and the Human Endocrine System: An Endocrine Society Scientific Statement,

10. Dezember 2024 | Opioide

Exogenous Opioids and the Human Endocrine System: An Endocrine Society Scientific Statement, Niki Karavitaki, Jeffrey J Bettinger, Nienke Biermasz, Mirjam Christ-Crain, Monica R Gadelha, Warrick J Inder, Elena Tsourdi, Sarah E Wakeman, Mari...

Opioidverordnungen bei Versicherten ohne Krebserkrankung in Deutschland – Daten der BARMER.

10. Dezember 2024 | Opioide

Opioidverordnungen bei Versicherten ohne Krebserkrankung in Deutschland – Daten der BARMER. Lappe, V., Grandt, D., Marschall, U. et al. Schmerz (2024). doi.org/10.1007/s00482-024-00852-8 https://link.spr...

mindzone. 15. Folge Dr. Schepper antwortet „Niedrigpotente Opiate / Opioide: Codein und Tilidin“

10. Dezember 2024 | Opioide

mindzone. 15. Folge Dr. Schepper antwortet „Niedrigpotente Opiate / Opioide: Codein und Tilidin“ Definition Opiat / Opioid: Opiate sind jene psychoaktive Substanzen, die schon seit Langem aus Opium, dem getrockneten Milchsaft des Schlafmohns (Pa...

Verordnung cannabisbasierter Arzneimittel: Fachgesellschaft gibt Praxishinweise

10. Dezember 2024 | Cannabis als Medizin

Verordnung cannabisbasierter Arzneimittel: Fachgesellschaft gibt Praxishinweise Berlin – Seit Oktober dürfen Ärztinnen und Ärzte mit 16 Facharzt- und Schwerpunktbezeichnungen Cannabisarzneimittel ohne vorherigen Antrag auf Kostenübernahme bei den...

Xylazine Pharmacokinetics in Patients Testing Positive for Fentanyl and Xylazine,

04. Dezember 2024 | Verschiedene

Xylazine Pharmacokinetics in Patients Testing Positive for Fentanyl and Xylazine, Yanchun Lin, Christopher W Farnsworth, Vahid Azimi, David B Liss, Michael E Mullins, Bridgit O Crews, Clinical Chemistry, 2024;, hvae163, doi.org/10.10...

Xylazine induces dopamine release and augments the effects of fentanyl.

04. Dezember 2024 | Verschiedene

Xylazine induces dopamine release and augments the effects of fentanyl. Trinko JR, Foscue E, Kong EM, Basu A, Corstens AM, Thompson SL, Kaye AP, Taylor JR, DiLeone RJ. J Clin Invest. 2024 Nov 15;134(22):e183354. doi: 10.1172/JCI18335...

Abuse potential of fentanyl and fentanyl analogues.

04. Dezember 2024 | Fentanyl

Abuse potential of fentanyl and fentanyl analogues. Thumma A, Mfoafo K, Babanejad N, Omidian A, Omidi Y, Omidian H. Bioimpacts. 2024;14(6):27691. doi: 10.34172/bi.2024.27691. Epub 2024 Mar 18. PMID: 39493900; PMCID: PMC11530972. htt...

Examining the Severity and Progression of Illicitly Manufactured Fentanyl Withdrawal: A Quasi-Experimental Comparison.

04. Dezember 2024 | Fentanyl

Examining the Severity and Progression of Illicitly Manufactured Fentanyl Withdrawal: A Quasi-Experimental Comparison. Sharma A, Dunn KE, Schmid-Doyle K, Dowell S, Kim N, Strain EC, Bergeria C. J Addict Med. 2024 Nov 26. doi: 10.1097...

Therapeutic Potential of Psychedelic Compounds for Substance Use Disorders.

04. Dezember 2024 | Verschiedene

Therapeutic Potential of Psychedelic Compounds for Substance Use Disorders. Valdez T, Patel V, Senesombath N, Hatahet-Donovan Z, Hornick M. Pharmaceuticals (Basel). 2024 Nov 5;17(11):1484. doi: 10.3390/ph17111484. PMID: 39598395; PMC...

Exploring the substitution of cannabis for alcohol and other drugs among a large convenience sample of people who use cannabis.

04. Dezember 2024 | Cannabis als Medizin

Exploring the substitution of cannabis for alcohol and other drugs among a large convenience sample of people who use cannabis. Wilkins C, Romeo J, Rychert M, Graydon-Guy T. Harm Reduct J. 2024 Nov 5;21(1):192. doi: 10.1186/s12954-02...

Nitazenes

04. Dezember 2024 | Opioide

Nitazenes Drug Science, UK, aufgerufen am 04.2.2024 https://www.drugscience.org.uk/nitazenes

Is the SCL90-based five-dimensional structure able to differentiate Heroin Use Disorder patients with low and high benzodiazepine dependence symptomatology?

02. Dezember 2024 | Benzodiazepine

Is the SCL90-based five-dimensional structure able to differentiate Heroin Use Disorder patients with low and high benzodiazepine dependence symptomatology? Angelo G. I. Maremmani, Filippo Della Rocca, Silvia Bacciardi, Mario Miccoli, and Icro Ma...

Medical Adjustment of Alcohol Use Disorder (AUD) with Opioids

02. Dezember 2024 | Alkohol

Medical Adjustment of Alcohol Use Disorder (AUD) with Opioids Albrecht Ulmer Heroin Addiction and Related Clinical Problems: 2024, 26, 57, doi.org/10.62401/2531-4122-2024-57 https://www.heroinaddictionrelatedclinicalproblems.org/article.php?id=...

Screened Out — How a Survey Change Sheds Light on Iatrogenic Opioid Use Disorder

24. November 2024 | Opioide

Screened Out — How a Survey Change Sheds Light on Iatrogenic Opioid Use Disorder Andrew Kolodny, M.D., and Robert M. Bohler, Ph.D., M.P.H. NEJM, Published November 6, 2024, DOI: 10.1056/NEJMp2410911 https://www.nejm.org/doi/full/10.1056/N...

The alcohol harm paradox: is it valid for self-reported alcohol harms and does hazardous drinking pattern matter?.

22. November 2024 | Alkohol

The alcohol harm paradox: is it valid for self-reported alcohol harms and does hazardous drinking pattern matter?. Rossow, I., Bye, E.K. BMC Public Health 24, 3053 (2024). doi.org/10.1186/s12889-024-20530-9 https://bmcpublichea...

USA/Iran. Tehran’s Tactical Knockout: Weaponized Pharmaceutical-Based Agents

16. November 2024 | Fentanyl

USA/Iran. Tehran’s Tactical Knockout: Weaponized Pharmaceutical-Based Agents Combating Terrorism Center, CTS Sentinel, October 2024, Volume 17, Issue 9 https://ctc.westpoint.edu/tehrans-tactical-knockout-weaponized-pharmaceutical-based-agents/

Trends und Risikofaktoren des Nikotinkonsums im Kindes- und Jugendalter

16. November 2024 | Nikotin

Trends und Risikofaktoren des Nikotinkonsums im Kindes- und Jugendalter Ergebnisse des Präventionsradars von 2016 bis 2024 Trends in and risk factors for nicotine consumption in childhood and adolescence—findings of the “Prevention Radar,” a sur...

The association between benzodiazepine co-prescription, opioid agonist treatment and mortality: a systematic review.

11. November 2024 | Benzodiazepine

The association between benzodiazepine co-prescription, opioid agonist treatment and mortality: a systematic review. Hestevik CH, Evensen LH, Kornør H, Skeie I. BMC Psychiatry. 2024 Oct 28;24(1):741. doi: 10.1186/s12888-024-06191-3. ...

Clinical Outcomes of Benzodiazepine Prescribing for People Receiving Opioid Agonist Treatment: A Systematic Review of the Evidence.

11. November 2024 | Benzodiazepine

Clinical Outcomes of Benzodiazepine Prescribing for People Receiving Opioid Agonist Treatment: A Systematic Review of the Evidence. Matheson C, Vucic C, Dumbrell J, Robertson R, Ritchie T, Duncan C, Kessavalou K, Woolston C, Schofield J.&nb...

Tranq Dope: Characterization of an ED cohort treated with a novel opioid withdrawal protocol in the era of fentanyl/xylazine.

11. November 2024 | Fentanyl

Tranq Dope: Characterization of an ED cohort treated with a novel opioid withdrawal protocol in the era of fentanyl/xylazine. London K, Li Y, Kahoud JL, Cho D, Mulholland J, Roque S, Stugart L, Gillingham J, Borne E, Slovis B. Am J E...

Medications for Opioid Use Disorder Remain Effective as Highly Potent Synthetic Opioids Permeate North American Illicit Drug Supplies

11. November 2024 | Fentanyl

Medications for Opioid Use Disorder Remain Effective as Highly Potent Synthetic Opioids Permeate North American Illicit Drug Supplies Over the last ten years, highly potent synthetic opioids (HPSO) like fentanyl and fentanyl analogues have overta...

"Zombieland" in Philadelphia: Einblick in die Drogen-Hölle von Kensington. (Video)

11. November 2024 | Fentanyl

"Zombieland" in Philadelphia: Einblick in die Drogen-Hölle von Kensington. (Video) Die Opioid-Krise in den USA treibt in Kensington, Philadelphia tausende Menschen auf die Straße. Ein RTL-Team begleitet mehrere Menschen in ihrem Kampf gegen die D...

Sachsen-Anhalt/Gesundheit/Drogen: Opioid Fentanyl ist in Sachsen-Anhalt im Umlauf

11. November 2024 | Fentanyl

Sachsen-Anhalt/Gesundheit/Drogen: Opioid Fentanyl ist in Sachsen-Anhalt im Umlauf Das Opioid Fentanyl war bisher im Zusammenhang mit einer Drogenwelle in den USA bekannt. Nun ist es in Deutschland im Umlauf - auch in Sachsen-Anhalt werden mehr Fä...

Field and laboratory perspectives on fentanyl and carfentanil decontamination.

11. November 2024 | Fentanyl

Field and laboratory perspectives on fentanyl and carfentanil decontamination. Lindén P, Mörén L, Qvarnström J, Forsgren N, Engdahl CS, Engqvist M, Henych J, Tengel T, Österlund L, Thors L, Larsson A, Johansson S. Sci Rep. 2024 Oct 2...

Fentanyl: New Wave, New Age, New Addiction?

11. November 2024 | Fentanyl

Fentanyl: New Wave, New Age, New Addiction? Juli A, Juli G, Juli R, Juli L. Psychiatr Danub. 2024 Sep;36(Suppl 2):254-256. PMID: 39378480. https://www.psychiatria-danubina.com/UserDocsImages/pdf/dnb_vol36_noSuppl%202/dnb_vol36_noSup...

Temporal and spatial trends of fentanyl co-occurrence in the illicit drug supply in the United States: a serial cross-sectional analysis.

11. November 2024 | Fentanyl

Temporal and spatial trends of fentanyl co-occurrence in the illicit drug supply in the United States: a serial cross-sectional analysis. Lim TY, Dong H, Stringfellow E, Hasgul Z, Park J, Glos L, Kazemi R, Jalali MS. Lancet Reg Healt...

USA. San Francisco auf Fentanyl (Video)

11. November 2024 | Fentanyl

USA. San Francisco auf Fentanyl (Video) Angie, 42 Jahre alt, sitzt den ganzen Tag in ihrem Zelt und nimmt eine Dosis Drogen nach der anderen. Sie ist nur eine von Tausenden Drogenabhängigen im Stadtteil Tenderloin, im Herzen von San Francisco. Di...

Effects of opium tincture on gastrointestinal function and motility in healthy volunteers: A magnetic resonance imaging study.

11. November 2024 | Opioide

Effects of opium tincture on gastrointestinal function and motility in healthy volunteers: A magnetic resonance imaging study. Mark EB, Okdahl T, Kahlke DG, Hansen LEM, Krogh K, Frøkjær JB, Drewes AM. Neurogastroenterol Motil. 2024 O...

Psychedelic and MDMA-Related Adverse Effects—A Call for Action.

11. November 2024 | Amphetamine

Psychedelic and MDMA-Related Adverse Effects—A Call for Action. Simonsson O, Johnson MW, Hendricks PS. JAMA Health Forum. 2024;5(11):e243630. doi:10.1001/jamahealthforum.2024.3630 https://jamanetwork.com/journals/jama-health-fo...

Psychedelics: From Cave Art to 21st-Century Medicine for Addiction.

11. November 2024 | Verschiedene

Psychedelics: From Cave Art to 21st-Century Medicine for Addiction. Vamvakopoulou IA, Nutt DJ. Eur Addict Res. 2024;30(5):302-320. doi: 10.1159/000540062. Epub 2024 Sep 25. PMID: 39321788; PMCID: PMC11527458. https://pmc.ncbi.nlm.nih.gov/...

Non-opioid psychiatric medications for chronic pain: systematic review and meta-analysis.

11. November 2024 | Verschiedene

Non-opioid psychiatric medications for chronic pain: systematic review and meta-analysis. Ayub S, Bachu AK, Jain L, Parnia S, Bhivandkar S, Ahmed R, Kaur J, Karlapati S, Prasad S, Kochhar H, Ayisire OE, Mitra S, Ghosh B, Srinivas S, Ashraf ...

Alkohol - Zufuhr in Deutschland, gesundheitliche sowie soziale Folgen und Ableitung von Handlungsempfehlungen

11. November 2024 | Alkohol

Alkohol - Zufuhr in Deutschland, gesundheitliche sowie soziale Folgen und Ableitung von Handlungsempfehlungen Ziel des DGE-Positionspapiers ist es, unter Berücksichtigung der gesundheitlichen Wirkungen von Alkohol sowie weiterer Aspekte der Nachh...

Evaluation of E-Cigarette Use in Opioid-Dependent Patients in Maintenance Treatment.

11. November 2024 | Nikotin

Evaluation of E-Cigarette Use in Opioid-Dependent Patients in Maintenance Treatment. Rabl J, Specka M, Bonnet U, Irtürk Ö, Schifano F, Scherbaum N. Pharmacopsychiatry. 2024 Oct 30. doi: 10.1055/a-2414-5867. Epub ahead of print. PMID:...

Systematic review: The relationship between gabapentinoids, etizolam, and drug related deaths in Scotland.

11. November 2024 | Gabapentinoide

Systematic review: The relationship between gabapentinoids, etizolam, and drug related deaths in Scotland. Ciesluk B, Inglis DG, Parke A, Troup LJ (2024) PLoS ONE 19(10): e0310655. doi.org/10.1371/journal.pone.0310655 https://journa...

Characteristics of Non-Therapeutic Pregabalin Users Detected by a Community Pharmacies Network in a Region of Southern Europe.

11. November 2024 | Gabapentinoide

Characteristics of Non-Therapeutic Pregabalin Users Detected by a Community Pharmacies Network in a Region of Southern Europe. Perelló M, Rio-Aige K, Rius P, Pérez-Cano FJ, Rabanal M. J Clin Med. 2024 Oct 6;13(19):5942. doi: 10.3390/...

Pregabalin and gabapentin-induced heart failure.

11. November 2024 | Gabapentinoide

Pregabalin and gabapentin-induced heart failure. Barold SS, Barold DC, Hon R, Guglin M. Cardiol J. 2024 Oct 29. doi: 10.5603/cj.98754. Epub ahead of print. PMID: 39470187. https://journals.viamedica.pl/cardiology_journal/article/view/9875...

Experiences of misuse and symptoms of dependence among people who use gabapentinoids: A qualitative systematic review.

11. November 2024 | Gabapentinoide

Experiences of misuse and symptoms of dependence among people who use gabapentinoids: A qualitative systematic review. McNeilage AG, Sim A, Nielsen S, Murnion B, Ashton-James CE. Int J Drug Policy. 2024 Nov;133:104605. doi: 10.1016/j...

Understanding pregabalin misuse and dependence: Insights from a North Indian addiction treatment center.

11. November 2024 | Gabapentinoide

Understanding pregabalin misuse and dependence: Insights from a North Indian addiction treatment center. Ghosh A, Shukla S, Dhankar M, Naik SS, Subodh BN, Basu D. Indian J Psychiatry. 2024 Aug;66(8):723-728. doi: 10.4103/indianjpsychiatry....

Re: Crack erobert die Städte (Video)

11. November 2024 | Kokain

Re: Crack erobert die Städte (Video) Es ist billig und macht extrem süchtig: Crack. Das Kokain, aus dem Crack hergestellt wird, flutet Europa und ist so leicht zu bekommen wie noch nie. Konsumiert wird die Droge in vielen Städten, mitten in der Ö...

Schweiz. 3. Tagung Schadensminderung – Crack-/Freebase-Konsum K&A Zürich, Positionspapier der SSAM (Video)

11. November 2024 | Kokain

Schweiz. 3. Tagung Schadensminderung – Crack-/Freebase-Konsum K&A Zürich, Positionspapier der SSAM (Video) Crack-Konsum in den Zürcher Kontakt- und Anlaufstellen –Entwicklungen und Herausforderungen | Florian Meyer, Abteilungsleiter Schadensm...

BARMER-Suchtatlas – Kokainmissbrauch geradezu explodiert

11. November 2024 | Kokain

BARMER-Suchtatlas – Kokainmissbrauch geradezu explodiert Berlin, 1. November 2024 – Innerhalb von zehn Jahren hat sich die Zahl der Menschen mehr als verdreifacht, die wegen Kokainmissbrauchs in ärztlicher Behandlung sind. Das geht aus eine...

A qualitative study of psychological stress and coping among persons using crack cocaine.

11. November 2024 | Kokain

A qualitative study of psychological stress and coping among persons using crack cocaine. Duopah YA, Moran L, Elmusharaf K, Kelly D. BMC Psychol. 2024 Oct 7;12(1):537. doi: 10.1186/s40359-024-02032-w. PMID: 39375776; PMCID: PMC114573...

Verbot von Zigaretten könnte Lebenserwartung in der Gesamtbevölkerung steigern

11. November 2024 | Nikotin

Verbot von Zigaretten könnte Lebenserwartung in der Gesamtbevölkerung steigern Santiago de Compostela und Bergen – Ein Verbot des Verkaufs von Zigaretten an die nachwachsenden Generationen könnte bis Ende 2095 schätzungsweise 1,2 Millionen Todes...

Forecasting the effects of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050: a systematic analysis for the Global Burden of Disease Study 2021

11. November 2024 | Nikotin

Forecasting the effects of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050: a systematic analysis for the Global Burden of Disease Study 2021 Bryazka, Dana et al. The Lancet Public Health, Volume 9, Issue...

Evaluation of the teratogenic effects of pregabalin usage during pregnancy: A multicenter case-control study.

10. November 2024 | Gabapentinoide

Evaluation of the teratogenic effects of pregabalin usage during pregnancy: A multicenter case-control study. Kaskal M, Kuru B, Erkoseoglu I, Yilmaz H, Karadas B, Goren MZ. North Clin Istanb. 2024 Oct 3;11(5):460-465. doi: 10.14744/n...

Semaglutid und andere GLP-1-Agonisten könnten bei Drogensucht helfen

26. Oktober 2024 | Verschiedene

Semaglutid und andere GLP-1-Agonisten könnten bei Drogensucht helfen Chicago – US-Patienten mit einer Opiat- oder Alkoholabhängigkeit, denen zur Behandlung eines gleichzeitig bestehenden Typ 2-Diabetes oder einer Adipositas Semaglutid oder ein an...

Psychedelika könnten Therapieoption bei lebensbedrohlichen Krankheiten sein

26. Oktober 2024 | Verschiedene

Psychedelika könnten Therapieoption bei lebensbedrohlichen Krankheiten sein Basel – Menschen mit einer lebensbedrohlichen Krankheit leiden häufig unter Depressionssymptomen und existentiellen Ärzten. Eine Psychedelika-assistierte Therapie mit Psi...

Psychometric Properties of the German Version of the Benzodiazepine Dependence Self-Report Questionnaire

24. Oktober 2024 | Benzodiazepine

Psychometric Properties of the German Version of the Benzodiazepine Dependence Self-Report Questionnaire Johanna Heeg, Markus Wim Stratmann, Jörg Dirmaier, Uwe Verthein International Journal of Mental Health and Addiction, October 2024, DOI: 10....

USA. Feds warn about pink cocaine, also known as Tusi, in NYC. Here's what to know.

24. Oktober 2024 | Verschiedene

USA. Feds warn about pink cocaine, also known as Tusi, in NYC. Here's what to know. NEW YORK - The feds are issuing a new warning about a drug cocktail called pink cocaine. The feds say it's a popular party drug they're finding on New...

Cancer risk and legalisation of access to cannabis in the USA: overview of the evidence

24. Oktober 2024 | Cannabis als Rauschmittel

Cancer risk and legalisation of access to cannabis in the USA: overview of the evidence Nargis, Nigar et al. The Lancet Public Health, Volume 0, Issue 0 https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(24)00223-8/fulltextht...

Fentanyl, Heroin, Methamphetamine, and Cocaine Analyte Concentrations in Urine Drug Testing Specimens.

23. Oktober 2024 | Fentanyl

Fentanyl, Heroin, Methamphetamine, and Cocaine Analyte Concentrations in Urine Drug Testing Specimens. Huhn AS, Whitley P, Bolin BL, Dunn KE. JAMA Netw Open. 2024;7(10):e2441063. doi:10.1001/jamanetworkopen.2024.41063 https://j...

Inzidenz und Risikofaktoren für einen persistierenden Opioidgebrauch nach Operationen - Eine retrospektive Sekundärdatenanalyse

17. Oktober 2024 | Opioide

Inzidenz und Risikofaktoren für einen persistierenden Opioidgebrauch nach Operationen - Eine retrospektive Sekundärdatenanalyse The incidence and risk factors of persistent opioid use after surgery—a retrospective secondary data analysis Dreilin...

Medizinisches Cannabis: Verordnung ohne Genehmigung der Kasse möglich

17. Oktober 2024 | Cannabis als Medizin

Medizinisches Cannabis: Verordnung ohne Genehmigung der Kasse möglich Berlin – Ärzte dürfen vom heutigen Donnerstag an medizinisches Cannabis ohne Genehmigung der gesetzlichen Krankenversicherung (GKV) verordnen. Sie müssen dazu eine bestimmte F...

Neue „Designerdrogen“ fluten den Markt Ein Überblick über die Substanzen und ihre Gefahren

17. Oktober 2024 | Verschiedene

Neue „Designerdrogen“ fluten den Markt Ein Überblick über die Substanzen und ihre Gefahren Um Verbote zu umgehen, werden psychoaktive Substanzen immer wieder geringfügig chemisch modifiziert. Das Neue-psychoaktive-Stoffe-Gesetz erschwert di...

Koffeinpulver: Gefahr einer versehentlichen Überdosierung hoch

17. Oktober 2024 | Verschiedene

Koffeinpulver: Gefahr einer versehentlichen Überdosierung hoch Berlin – Schon ein bis zwei Teelöffel können tödlich sein: Das Bundesinstitut für Risikobewertung (BfR) warnt vor hochkonzentriertem Koffein in Pulverform, das im Handel als Nahrungse...

Deutscher Bundestag. Verordnungsentwicklungen von Opioiden in Deutschland

09. Oktober 2024 | Opioide

Deutscher Bundestag. Verordnungsentwicklungen von Opioiden in Deutschland Drucksache 20/12816, 20. Wahlperiode 04.09.2024 Antwort der Bundesregierung auf die Kleine Anfrage der Abgeordneten Ates Gürpinar, Susanne Ferschl, Gökay Akbulut, weiterer...

Cave verlängerte Schmerzbehandlung: Die Risiken der postoperativen Opioidtherapie kennen

07. Oktober 2024 | Opioide

Cave verlängerte Schmerzbehandlung: Die Risiken der postoperativen Opioidtherapie kennen Dtsch Arztebl 2024; 121(19): A-1238 / B-1057, Medizinreport Lenzen-Schulte, Martina https://www.aerzteblatt.de/archiv/241198

Xylazine Exacerbates Fentanyl-Induced Respiratory Depression and Bradycardia.

06. Oktober 2024 | Fentanyl

Xylazine Exacerbates Fentanyl-Induced Respiratory Depression and Bradycardia. Demery-Poulos C, Moore SC, Levitt ES, Anand JP, Traynor JR. bioRxiv [Preprint]. 2024 Aug 19:2024.08.16.608310. doi: 10.1101/2024.08.16.608310. PMID: 392290...

Buprenorphine-Precipitated Withdrawal Among Hospitalized Patients Using Fentanyl.

06. Oktober 2024 | Fentanyl

Buprenorphine-Precipitated Withdrawal Among Hospitalized Patients Using Fentanyl. Thakrar AP, Christine PJ, Siaw-Asamoah A, Spadaro A, Faude S, Snider CK, Delgado MK, Lowenstein M, Kampman K, Perrone J, Nelson LS, Kilaru AS. JAMA Net...

Precipitated Withdrawal in the Era of Street Fentanyl -The Important Thing Is to Not Stop Questioning.

06. Oktober 2024 | Fentanyl

Precipitated Withdrawal in the Era of Street Fentanyl -The Important Thing Is to Not Stop Questioning. Soares WE 3rd, Schoenfeld E, Friedmann PD. JAMA Netw Open. 2024 Sep 3;7(9):e2435857. doi: 10.1001/jamanetworkopen.2024.35857. PMID...

An unexpected place for a fentanyl patch.

06. Oktober 2024 | Fentanyl

An unexpected place for a fentanyl patch. Leenders MEC, Visser CC, Lange DW. Clin Toxicol (Phila). 2024 Sep 28:1-2. doi: 10.1080/15563650.2024.2407056. Epub ahead of print. PMID: 39340344. https://www.tandfonline.com/doi/full/10.108...

Peripheral opioid receptor antagonism alleviates fentanyl-induced cardiorespiratory depression and is devoid of aversive effects.

06. Oktober 2024 | Fentanyl

Peripheral opioid receptor antagonism alleviates fentanyl-induced cardiorespiratory depression and is devoid of aversive effects. Ruyle BC, Masud S, Kesaraju R, Tahirkheli M, Modh J, Angulo-Lopera S, Lintz T, Higginbotham JA, Massaly N, Mor...

How substance use preferences and practices relate to fentanyl exposure among people who use drugs in Rhode Island, USA.

06. Oktober 2024 | Fentanyl

How substance use preferences and practices relate to fentanyl exposure among people who use drugs in Rhode Island, USA. Shaw LC, Biello KB, Buxton JA, Goldman JE, Hadland SE, Sherman SG, Li Y, Macmadu A, Marshall BDL. Drug Alcohol D...

Fentanyl and Sudden Death-A Postmortem Perspective for Diagnosing and Predicting Risk.

06. Oktober 2024 | Fentanyl

Fentanyl and Sudden Death-A Postmortem Perspective for Diagnosing and Predicting Risk. Strenja I, Dadić-Hero E, Perković M, Šoša I. Diagnostics (Basel). 2024 Sep 9;14(17):1995. doi: 10.3390/diagnostics14171995. PMID: 39272779; PMCID:...

Correlates of fentanyl preference among people who use drugs in Rhode Island.

06. Oktober 2024 | Fentanyl

Correlates of fentanyl preference among people who use drugs in Rhode Island. Napoleon SC, Park CJ, Goldman J, Li Y, Buxton JA, Macmadu A, Biello KB, Noguchi J, Marshall BDL. Harm Reduct J. 2024 Sep 14;21(1):169. doi: 10.1186/s12954-...

Fentanyl-positive urine drug screens in the emergency department: Association with intentional opioid misuse and racial disparities.

06. Oktober 2024 | Fentanyl

Fentanyl-positive urine drug screens in the emergency department: Association with intentional opioid misuse and racial disparities. Shufflebarger EF, Reynolds LM, McNellage L, Booth JS, Brown J, Edwards AR, Li L, Robinett DA, Walter LA.&nb...

Can the the THC concentration predict the number of patients with cannabis-related diagnoses?

06. Oktober 2024 | Cannabis als Rauschmittel

Can the the THC concentration predict the number of patients with cannabis-related diagnoses? Manthey J, Rosenkranz M, Jonas B, Schwarzkopf L. Can Drug Alcohol Rev. 2024. doi.org/10.1111/dar.13923 https://onlinelibrary.wiley.com/doi...

Proof of Concept for High-Dose Cannabidiol Pretreatment to Antagonize Opioid Induced Persistent Apnea.

06. Oktober 2024 | Cannabis als Medizin

Proof of Concept for High-Dose Cannabidiol Pretreatment to Antagonize Opioid Induced Persistent Apnea. Wiese BM, Bondarenko E, Feldman JL. bioRxiv [Preprint]. 2024 Sep 14:2024.09.13.612358. doi: 10.1101/2024.09.13.612358. PMID: 39314...

Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study.

06. Oktober 2024 | Gabapentinoide

Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study. Muller S, Bailey J, Bajpai R, Helliwell T, Harrisson SA, Whit...

At the tipping point: Patient experiences of addiction to benzodiazepines and motivation to seek treatment.

06. Oktober 2024 | Benzodiazepine

At the tipping point: Patient experiences of addiction to benzodiazepines and motivation to seek treatment. Burmester S, Krüger C, Franck J, Lindberg MH, Westman J. J Subst Use Addict Treat. 2024 Sep 5;167:209508. doi: 10.1016/j.josa...

Incidence, Timing and Social Correlates of the Development of Opioid Use Disorder Among Clients Seeking Treatment for an Alcohol Use Problem: Changes Over the Three Waves of the Opioid Epidemic.

06. Oktober 2024 | Alkohol

Incidence, Timing and Social Correlates of the Development of Opioid Use Disorder Among Clients Seeking Treatment for an Alcohol Use Problem: Changes Over the Three Waves of the Opioid Epidemic. Falls Z, Zhang X, Elkin PL, Jacobs D, Bednarc...

Detection of N-desethyl etonitazene in a drug checking sample: Chemical analysis and pharmacological characterization of a recent member of the 2-benzylbenzimidazole "nitazene" class.

06. Oktober 2024 | Opioide

Detection of N-desethyl etonitazene in a drug checking sample: Chemical analysis and pharmacological characterization of a recent member of the 2-benzylbenzimidazole "nitazene" class. Monti MC, De Vrieze LM, Vandeputte MM, Persson M, Gréen ...

Novel insights into mechanisms of inhibition of colonic motility by loperamide.

06. Oktober 2024 | Opioide

Novel insights into mechanisms of inhibition of colonic motility by loperamide. Parkar N, Spencer NJ, Wiklendt L, Olson T, Young W, Janssen P, McNabb WC, Dalziel JE. Front Neurosci. 2024 Aug 29;18:1424936. doi: 10.3389/fnins.2024.142...

The development and validation of a knowledge, attitude, and practice questionnaire of methamphetamine use.

06. Oktober 2024 | Amphetamine

The development and validation of a knowledge, attitude, and practice questionnaire of methamphetamine use. Azmi AD, Wahab S, Abdul Kadir NB, Abdul Wahab NA, Razak RA. Sci Rep. 2024 Sep 18;14(1):21835. doi: 10.1038/s41598-024-73126-z...

Semaglutide and Opioid Overdose Risk in Patients With Type 2 Diabetes and Opioid Use Disorder.

06. Oktober 2024 | Verschiedene

Semaglutide and Opioid Overdose Risk in Patients With Type 2 Diabetes and Opioid Use Disorder. Wang W, Volkow ND, Wang Q, et al. JAMA Netw Open. 2024;7(9):e2435247. doi:10.1001/jamanetworkopen.2024.35247 https://jamanetwork.com...

JCOIN Launches Xylazine 101 Video Explainer

06. Oktober 2024 | Verschiedene

JCOIN Launches Xylazine 101 Video Explainer Xylazine is a non-opioid sedative not approved for human use that is increasingly found as an adulterant in the illicit drug supply and is contributing to record levels of overdose deaths. The Xy...

Nitrous-Oxide: What is it good for?

06. Oktober 2024 | Verschiedene

Nitrous-Oxide: What is it good for? Discovered in 1722 by Dr Joseph Priestley, nitrous oxide (N2O) is now an essential medicine and a popular recreational drug. Nitrous oxide is simply structured, with just two nitrogen atoms ...

Psychedelic research at a crossroads.

06. Oktober 2024 | Verschiedene

Psychedelic research at a crossroads. Stacey B. Armstrong, Alan K. Davis Science385,1255-1255(2024).DOI:10.1126/science.adt1024 https://www.science.org/doi/10.1126/science.adt1024

Swiss Psychedelic Side Effects Inventory (SPSI) - Anleitung für Kliniker

06. Oktober 2024 | Verschiedene

Swiss Psychedelic Side Effects Inventory (SPSI) - Anleitung für Kliniker SPSI Version 1.0 Calder & Hasler 2024 1 https://ars.els-cdn.com/content/image/1-s2.0-S0165032724013132-mmc4.pdf

Validation of the Swiss Psychedelic Side Effects Inventory: Standardized assessment of adverse effects in studies of psychedelics and MDMA.

06. Oktober 2024 | Verschiedene

Validation of the Swiss Psychedelic Side Effects Inventory: Standardized assessment of adverse effects in studies of psychedelics and MDMA. Calder AE, Hasler G. J Affect Disord. 2024 Nov 15;365:258-264. doi: 10.1016/j.jad.2024.08.091...

Psychedelika

06. Oktober 2024 | Verschiedene

Psychedelika Psychedelika umfassen verschiedene Substanzen wie LSD (Lysergsäurediethylamid), halluzinogene Pilze (Psilocybin, Psilocybe), Zauberpilze (magic mushrooms) wie der Peyotl, der San Pedro usw. (Meskalin), Ayahuasca (DMT) und noch viele ...

Analgetica. Welche Schmerzmittel werden am meisten verschrieben? (Infografik)

28. September 2024 | Opioide

Analgetica. Welche Schmerzmittel werden am meisten verschrieben? (Infografik) "In Deutschland ist die Zahl der Patienten, die opioidhaltige Schmerzmittel nehmen, auffällig hoch", schreibt der Spiegel in einem kürzlich veröffentlichten Artikel. Gr...

Gefährliche neue Droge Polizei warnt Jugendliche vor »Görke«

28. September 2024 | Cannabis als Rauschmittel

Gefährliche neue Droge Polizei warnt Jugendliche vor »Görke« Der Name klingt nicht unbedingt gefährlich. Aber was sich dahinter verbirgt, ist es schon: »Görke« kann schwere Schäden verursachen. Immer mehr Jugendliche konsumieren die Droge d...

Drogen in E-Zigaretten: Polizei im Emsland warnt vor "Görke"

28. September 2024 | Cannabis als Rauschmittel

Drogen in E-Zigaretten: Polizei im Emsland warnt vor "Görke" Die Polizei im Emsland und in der Grafschaft warnt vor dem Konsum einer neuen Droge namens "Görke". In den letzten Monaten hätten sich die Berichte über die gefährliche Substanz gehäuft...

Cannabis, cannabinoids and health: a review of evidence on risks and medical benefits.

25. September 2024 | Cannabis als Medizin

Cannabis, cannabinoids and health: a review of evidence on risks and medical benefits. Hoch E, Volkow ND, Friemel CM, Lorenzetti V, Freeman TP, Hall W. Eur Arch Psychiatry Clin Neurosci. 2024 Sep 19. doi: 10.1007/s00406-024-01880-2. ...

Cannabis, cannabinoids and health: a review of evidence on risks and medical benefits.

25. September 2024 | Cannabis als Rauschmittel

Direct-to-Consumer Educational Brochures to Promote Gabapentinoid Deprescribing in Older Adults.

25. September 2024 | Gabapentinoide

Direct-to-Consumer Educational Brochures to Promote Gabapentinoid Deprescribing in Older Adults. Gingras M, Dubé R, Williams J, et al. JAMA Intern Med. Published online September 23, 2024. doi:10.1001/jamainternmed.2024.4748 ht...

Depressionen: Wirkung von Psilocybin hält über sechs Monate an

25. September 2024 | Verschiedene

Depressionen: Wirkung von Psilocybin hält über sechs Monate an London – Die zweimalige Gabe der psychedelischen Droge Psilocybin hat in einer randomisierten Studie die Symptome von Patienten mit Majordepression über mindestens 6 Monate gelindert....

Effect of psilocybin versus escitalopram on depression symptom severity in patients with moderate-to-severe major depressive disorder: observational 6-month follow-up of a phase 2, double-blind, randomised, controlled trial

25. September 2024 | Verschiedene

Effect of psilocybin versus escitalopram on depression symptom severity in patients with moderate-to-severe major depressive disorder: observational 6-month follow-up of a phase 2, double-blind, randomised, controlled trial Erritzoe, David et al....

What is the Transmucosal Immediate-Release Fentanyl (TIRF) REMS?

22. September 2024 | Fentanyl

What is the Transmucosal Immediate-Release Fentanyl (TIRF) REMS? The Transmucosal Immediate Release Fentanyl (TIRF) Risk Evaluation and Mitigation Strategy (REMS) Program is an FDA-required program designed to ensure informed risk-benefit decisio...

Schweiz. Bis zu 500-mal stärker als Heroin. Neue Droge in Luzern entdeckt: Sie tötet schon in kleinen Dosen

22. September 2024 | Opioide

Schweiz. Bis zu 500-mal stärker als Heroin. Neue Droge in Luzern entdeckt: Sie tötet schon in kleinen Dosen In vielen Ländern sind synthetische Opioide wie Fentanyl gefürchtet. Sie sorgen für Tausende von Drogentoten. In Luzern wurde eine weltwei...

A qualitative evaluation of a fentanyl patch safer supply program in Vancouver, Canada. (2)

10. September 2024 | Fentanyl

A qualitative evaluation of a fentanyl patch safer supply program in Vancouver, Canada. Norton A, Ivsins A, Holliday E, Sutherland C, Kerr T, Kennedy MC. Int J Drug Policy. 2024 Aug 17;131:104547. doi: 10.1016/j.drugpo.2024.104547. E...

Synthetische Drogen: Der Rausch wird krasser

10. September 2024 | Verschiedene

Synthetische Drogen: Der Rausch wird krasser Crack, Fentanyl, Ketamin: Synthetische Drogen kosten immer mehr Menschen das Leben. Wie ein Chemiker des Bundeskriminalamtes vom Labor aus die Drogenmafia jagt. (Die Zeit, 38/24, aktualisiert am ...

Berlin. Kreuzberg: Insider packt aus – neue Todes-Droge auf dem Vormarsch

09. September 2024 | Fentanyl

Berlin. Kreuzberg: Insider packt aus – neue Todes-Droge auf dem Vormarsch Teile von Kreuzberg sind bereits jetzt völlig von Drogen überschwemmt. Doch es könnte bald noch schlimmer werden. (Berlin live, 09.09.2024) https://www.berlin-live.de/berl...

Pharmacogenomics of 3,4-Methylenedioxymethamphetamine (MDMA): A Narrative Review of the Literature.

09. September 2024 | Amphetamine

Pharmacogenomics of 3,4-Methylenedioxymethamphetamine (MDMA): A Narrative Review of the Literature. Drevin G, Pena-Martin M, Bauduin A, Baudriller A, Briet M, Abbara C. Pharmaceutics. 2024 Aug 20;16(8):1091. doi: 10.3390/pharmaceutics16081...

Systematic review protocol to determine the most effective pharmacological and non-pharmacological interventions for the management of acute methamphetamine toxicity.

09. September 2024 | Amphetamine

Systematic review protocol to determine the most effective pharmacological and non-pharmacological interventions for the management of acute methamphetamine toxicity. Ghosh SM, Kung JY, Crockford D, Harpur L, Tanguay R, Dyer D, Lang E, Ayas...

Expert opinions on implementation of MDMA-assisted therapy in Europe: critical appraisal towards training, clinical practice, and regulation.

09. September 2024 | Amphetamine

Expert opinions on implementation of MDMA-assisted therapy in Europe: critical appraisal towards training, clinical practice, and regulation. Herpers J, Maximets N, van Dongen NNN, Zijlmans J, Vermetten E. Eur J Psychotraumatol. 2024...

Controversies in Assessment, Diagnosis, and Treatment of Kratom Use Disorder.

09. September 2024 | Verschiedene

Controversies in Assessment, Diagnosis, and Treatment of Kratom Use Disorder. Smith KE, Epstein DH, Weiss ST. Curr Psychiatry Rep. 2024 Sep;26(9):487-496. doi: 10.1007/s11920-024-01524-1. Epub 2024 Aug 13. PMID: 39134892; PMCID: PMC1...

Kappa-opioid receptor stimulation in the nucleus accumbens shell and ethanol drinking: Differential effects by rostro-caudal location and level of drinking.

09. September 2024 | Alkohol

Kappa-opioid receptor stimulation in the nucleus accumbens shell and ethanol drinking: Differential effects by rostro-caudal location and level of drinking. Pirino BE, Hawks A, Carpenter BA, Candelas PG, Gargiulo AT, Curtis GR, Karkhanis AN...

Mechanism of gabapentinoid potentiation of opioid effects on cyclic AMP signaling in neuropathic pain.

09. September 2024 | Gabapentinoide

Mechanism of gabapentinoid potentiation of opioid effects on cyclic AMP signaling in neuropathic pain. Garza-Carbajal A, Bavencoffe A, Herrera JJ, Johnson KN, Walters ET, Dessauer CW. Proc Natl Acad Sci U S A. 2024 Aug 20;121(34):e24...

'We need more support and doctors that understand the process of tapering …': A content analysis of free-text responses to a questionnaire on discontinuing long-term benzodiazepine receptor agonist use.

09. September 2024 | Benzodiazepine

'We need more support and doctors that understand the process of tapering …': A content analysis of free-text responses to a questionnaire on discontinuing long-term benzodiazepine receptor agonist use. Lynch T, Ryan C, Huff C, Foster DE, C...

Umgang mit Neuen Psychoaktiven Substanzen (NPS) in der Notfallmedizin.

09. September 2024 | Neue Psychoaktive Substanzen

Umgang mit Neuen Psychoaktiven Substanzen (NPS) in der Notfallmedizin. Notfall Rettungsmed 26, 142 (2023). https://doi.org/10.1007/s10049-022-01117-6

Neue Psychoaktive Substanzen in der Notfallmedizin

09. September 2024 | Neue Psychoaktive Substanzen

Neue Psychoaktive Substanzen in der Notfallmedizin Neue Psychoaktive Substanzen in der Notfallmedizin R. Marinowitz, J. Strube, A. Schaper Notfall + Rettungsmedizin | Ausgabe 8/2023 https://www.springermedizin.de/notfallmedizin...

Teils hochpotent und gefährlich: Opioide – was Apotheker über Nitazene wissen sollten

09. September 2024 | Opioide

Teils hochpotent und gefährlich: Opioide – was Apotheker über Nitazene wissen sollten „Untergrundchemiker“ liefern sich seit Jahren ein Katz-und-Maus-Spiel mit Strafverfolgern. Sie synthetisieren neue psychoaktive Substanzen (NPS), indem sie die ...

Medetomidine Infiltrates the US Illicit Opioid Market.

05. September 2024 | Verschiedene

Medetomidine Infiltrates the US Illicit Opioid Market. Palamar JJ, Krotulski AJ. JAMA. Published online September 04, 2024. doi:10.1001/jama.2024.15992 Abstract https://jamanetwork.com/journals/jama/article-abstract/2823005

Under the Radar: Are Nitazenes More Prevalent Than Known?

05. September 2024 | Opioide

Under the Radar: Are Nitazenes More Prevalent Than Known? Nitazenes, a class of synthetic opioids, are increasingly found everywhere. While (still) relatively obscure, detections of these opioids have been reported in Europe, Canada, Australia, B...

A Doctor Gives the Facts on Fentanyl

05. September 2024 | Fentanyl

A Doctor Gives the Facts on Fentanyl People are understandably scared about fentanyl (a strong, potent opioid) – but panic and misinformation can hurt us. We need the facts, without stigma, to keep us safer. So we spoke with Dr. David Goodman-Mez...

USA/SF. Weak fentanyl named ‘soap’ is flooding the market — and spurring robberies

05. September 2024 | Fentanyl

USA/SF. Weak fentanyl named ‘soap’ is flooding the market — and spurring robberies Fentanyl in San Francisco isn’t what it used to be, drug users say. A more diluted version of the lethal opioid, called “soap” in some circles, is fueling fits of ...

Designer drugs: past history and future prospects.

05. September 2024 | Verschiedene

Designer drugs: past history and future prospects. Henderson GL. J Forensic Sci. 1988 Mar;33(2):569-75. PMID: 3286815. Abstract https://pubmed.ncbi.nlm.nih.gov/3286815/

A lot testing protocol for quality assurance of fentanyl test strips for harm reduction applications.

04. September 2024 | Fentanyl

A lot testing protocol for quality assurance of fentanyl test strips for harm reduction applications. Fernando H, Amate A, Hayes KL, Whitehead HD, Desnoyers C, Uzobuife E, Denchfield MS, Whitelatch B, Lieberman M. Harm Reduct J. 2024 Aug 2...

Is there a role for vaccines in combatting the opioid epidemic?

04. September 2024 | Opioide

Is there a role for vaccines in combatting the opioid epidemic? Norton E. Vaccine Insights. 2024 May;3(3):83-89. doi: 10.18609/vac.2024.017. Epub 2024 May 9. PMID: 39156761; PMCID: PMC11329228. https://www.insights.bio/vaccine-insig...

Gabapentinoids increase the potency of fentanyl and heroin and decrease the potency of naloxone to antagonize fentanyl and heroin in rats discriminating fentanyl.

04. September 2024 | Gabapentinoide

Gabapentinoids increase the potency of fentanyl and heroin and decrease the potency of naloxone to antagonize fentanyl and heroin in rats discriminating fentanyl. Hiranita T, Flynn SM, Grisham AK, Mijares AE, Murphy EN, France CP. J ...

A qualitative evaluation of a fentanyl patch safer supply program in Vancouver, Canada.

04. September 2024 | Fentanyl

Frankfurt. Nachfrage steigt - Dealer über Fentanyl: "Leute zwischen 16 und 20 sind verrückt danach"

04. September 2024 | Fentanyl

Frankfurt. Nachfrage steigt - Dealer über Fentanyl: "Leute zwischen 16 und 20 sind verrückt danach" Fentanyl wirkt bis zu 100 Mal stärker als Heroin – und ist somit extrem gefährlich. Dennoch steigt die Nachfrage in Deutschland stetig an. (...

Providers' knowledge and perception of xylazine in the unregulated drug supply: a sequential explanatory mixed-methods study.

04. September 2024 | Verschiedene

Providers' knowledge and perception of xylazine in the unregulated drug supply: a sequential explanatory mixed-methods study. Hill K, Minahan-Rowley R, Biegacki ET, Heimer R, Sue KL. Harm Reduct J. 2024 Aug 16;21(1):148. doi: 10.1186...

Wie Ketamin Depressionen lindert

04. September 2024 | Verschiedene

Wie Ketamin Depressionen lindert Hangzhou/China – Die lateralen Habenulae, 2 kaum erbsengroße Kerngebiete in der Nähe der Zirbeldrüse, könnten der Wirkort des Anästhetikums Ketamin sein, wenn es in niedriger Dosis Depressionen innerhalb kurzer Ze...

Psilocybin bei Depressionen wirksamer als Placebo

04. September 2024 | Verschiedene

Psilocybin bei Depressionen wirksamer als Placebo Taipei – Eine Behandlung mit dem Psychedelikum Psilocybin könnte für die Behandlung depressiver Symptome vielversprechend sein. Zu diesem Ergebnis kommt eine taiwanesische Arbeitsgruppe nach einer...

Comparative oral monotherapy of psilocybin, lysergic acid diethylamide, 3,4-methylenedioxymethamphetamine, ayahuasca, and escitalopram for depressive symptoms: systematic review and Bayesian network meta-analysis

04. September 2024 | Verschiedene

Comparative oral monotherapy of psilocybin, lysergic acid diethylamide, 3,4-methylenedioxymethamphetamine, ayahuasca, and escitalopram for depressive symptoms: systematic review and Bayesian network meta-analysis Hsu T, Tsai C, Kao Y, Thomp...

CANNabinoid Drug Interaction Review (CANN- DIR® - Überprüfung der Wechselwirkungen zwischen Cannabinoiden und Arzneimitteln

31. August 2024 | Cannabis als Medizin

CANNabinoid Drug Interaction Review (CANN- DIR® - Überprüfung der Wechselwirkungen zwischen Cannabinoiden und Arzneimitteln CANNabinoid Drug Interaction Review (CANN-DIR®) wurde entwickelt, um potenzielle Wechselwirkungen zwischen Cannabiswirksto...

Facts about Fentanyl: Understanding the Risks (Video)

31. August 2024 | Fentanyl

Facts about Fentanyl: Understanding the Risks (Video) Addiction Policy Forum’s new video explainer, Facts about Fentanyl: Understanding the Risks, highlights the alarming increase of synthetic opioids like fentanyl, overdose risks, the increase i...

Why Is Fentanyl Driving Overdose Deaths?

17. August 2024 | Fentanyl

Why Is Fentanyl Driving Overdose Deaths? A Yale Medicine addiction medicine specialist discusses how the synthetic opioid became a problem. (Yale Medicine, USA, 18.02.2024) https://www.yalemedicine.org/news/fentanyl-driving-overdoses

Hoffnung geplatzt: FDA lehnt Zulassungsantrag für Ecstasy-Medikament bei PTBS ab – das kritisieren deutsche Experten

17. August 2024 | Amphetamine

Hoffnung geplatzt: FDA lehnt Zulassungsantrag für Ecstasy-Medikament bei PTBS ab – das kritisieren deutsche Experten Die US-amerikanische Arzneimittelbehörde FDA hat die Zulassung eines Medikaments, das auf der psychoaktiv wirkenden Substanz...

Auch geringe Mengen Alkohol erhöhen Erkrankungsrisiken

17. August 2024 | Alkohol

Auch geringe Mengen Alkohol erhöhen Erkrankungsrisiken Bonn – Es gibt keine risikofreie Menge für einen unbedenklichen Konsum von Alkohol. Selbst geringe Mengen können das Risiko für verschiedene Krankheiten erhöhen und damit die Gesundheit gefäh...

Zahl der Drogentoten durch Fentanyl steigt in Nordrhein-Westfalen wieder an

13. August 2024 | Fentanyl

Zahl der Drogentoten durch Fentanyl steigt in Nordrhein-Westfalen wieder an Düsseldorf – Die Zahl der Menschen, die im Zusammenhang mit der Droge Fentanyl und anderen synthetischen Opioiden gestorben sind, ist in Nordrhein-Westfalen (NRW) seit 2...

PTBS: FDA lehnt MDMA-basiertes Medikament ab – Journal zieht Studien zurück

13. August 2024 | Amphetamine

PTBS: FDA lehnt MDMA-basiertes Medikament ab – Journal zieht Studien zurück Silver Spring/Maryland – Ein umstrittener neuer Behandlungsansatz gegen posttraumatische Belastungsstörung mit der auch als Ecstasy bekannten chemischen Verbindung MDMA ...

Opioid-Based Haptens: Development of Immunotherapy.

11. August 2024 | Opioide

Opioid-Based Haptens: Development of Immunotherapy. Hosztafi S, Galambos AR, Köteles I, Karádi DÁ, Fürst S, Al-Khrasani M. Int J Mol Sci. 2024 Jul 16;25(14):7781. doi: 10.3390/ijms25147781. PMID: 39063024; PMCID: PMC11277321. https:...

Changes in cannabis involvement in emergency department visits for anxiety disorders after cannabis legalization: a repeated cross-sectional study.

11. August 2024 | Cannabis als Rauschmittel

Changes in cannabis involvement in emergency department visits for anxiety disorders after cannabis legalization: a repeated cross-sectional study. McCarthy SDS, Xiao J, Pugliese M, Perrault-Sequeira L, Myran DT. Lancet Reg Heal...

Assessing rates and predictors of cannabis-associated psychotic symptoms across observational, experimental and medical research.

11. August 2024 | Cannabis als Rauschmittel

Assessing rates and predictors of cannabis-associated psychotic symptoms across observational, experimental and medical research. Schoeler T, Baldwin JR, Martin E, Barkhuizen W, Pingault JB. Nat Ment Health. 2024;2(7):865-876. doi: 1...

Cannabis Hyperemesis Syndrome: What Do We Know?

11. August 2024 | Cannabis als Rauschmittel

Cannabis Hyperemesis Syndrome: What Do We Know? Shine D, Goodin A. Med Cannabis Cannabinoids. 2024 May 3;7(1):86-90. doi: 10.1159/000539182. PMID: 39015607; PMCID: PMC11250556. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11250556/

Lachgas -- kurzer Rausch mit langfristigen Folgen

11. August 2024 | Verschiedene

Lachgas -- kurzer Rausch mit langfristigen Folgen Für wenige Minuten steigt die Stimmung. Das Treibmittel Distickstoffmonoxid, besser bekannt als Lachgas, wird auch zu Rauschzwecken inhaliert. Doch langfristig kann der Konsum schwere Nervenschäde...

Reported Xylazine Use Among Adults Aged ≥18 Years Evaluated for Substance Use Treatment - United States, July 2022-September 2023.

11. August 2024 | Verschiedene

Reported Xylazine Use Among Adults Aged ≥18 Years Evaluated for Substance Use Treatment - United States, July 2022-September 2023. Jiang X, Connolly S, Strahan AE, Rivera Blanco L, Mikosz CA, Guy GP Jr, Dowell D. MMWR Morb Mortal Wkl...

Xylazine is an agonist at kappa opioid receptors and exhibits sex-specific responses to opioid antagonism.

11. August 2024 | Verschiedene

Xylazine is an agonist at kappa opioid receptors and exhibits sex-specific responses to opioid antagonism. Bedard ML, Huang XP, Murray JG, Nowlan AC, Conley SY, Mott SE, Loyack SJ, Cline CA, Clodfelter CG, Dasgupta N, Krumm B, Roth BL, McEl...

Verschreibung von Cannabisarzneimitteln an Selbstzahlende - Auswertung der in Apotheken vorgelegten Rezepte

11. August 2024 | Cannabis als Medizin

Verschreibung von Cannabisarzneimitteln an Selbstzahlende - Auswertung der in Apotheken vorgelegten Rezepte The prescribing of cannabis drugs to self-payers—an evaluation of prescriptions presented to pharmacies Dtsch Arztebl Int 2024; 121: 338-...

The Prescribing of Cannabis Drugs to Self-Payers.

11. August 2024 | Cannabis als Medizin

The Prescribing of Cannabis Drugs to Self-Payers. Cremer-Schaeffer P, Langer S. Dtsch Arztebl Int. 2024 May 17;121(10):338-339. doi: 10.3238/arztebl.m2024.0026. PMID: 38973404. https://www.aerzteblatt.de/int/archive/article/239109

Age-related Patterns of Medical Cannabis Use: A Survey of Authorized Patients in Canada.

11. August 2024 | Cannabis als Medizin

Age-related Patterns of Medical Cannabis Use: A Survey of Authorized Patients in Canada. Walker M, Lake S, Tempero J, Ong K, Lucas P. Cannabis. 2024 Jun 26;7(2):135-149. doi: 10.26828/cannabis/2024/000208. PMID: 38975599; PMCID: PMC1122597...

Acute effects of cannabigerol on anxiety, stress, and mood: a double-blind, placebo-controlled, crossover, field trial.

11. August 2024 | Cannabis als Medizin

Acute effects of cannabigerol on anxiety, stress, and mood: a double-blind, placebo-controlled, crossover, field trial. Cuttler C, Stueber A, Cooper ZD, Russo E. Sci Rep. 2024 Jul 13;14(1):16163. doi: 10.1038/s41598-024-66879-0. PMID...

Use and perceptions of Cannabidiol among individuals in treatment for opioid use disorder.

11. August 2024 | Cannabis als Medizin

Use and perceptions of Cannabidiol among individuals in treatment for opioid use disorder. Kudrich C, Chen R, Meng Y, Bachi K, Hurd YL. Harm Reduct J. 2024 Jul 17;21(1):135. doi: 10.1186/s12954-024-01051-5. PMID: 39020418; PMCID: PMC...

Overview of global monitoring systems for the side effects and adverse events associated with medicinal cannabis use: a scoping review using a systematic approach.

11. August 2024 | Cannabis als Medizin

Overview of global monitoring systems for the side effects and adverse events associated with medicinal cannabis use: a scoping review using a systematic approach. Wang RQ, Bonomo YA, Hallinan CM. BMJ Open. 2024 Jul 18;14(7):e085166....

The attitudes, knowledge and confidence of healthcare professionals about cannabis-based products.

11. August 2024 | Cannabis als Medizin

The attitudes, knowledge and confidence of healthcare professionals about cannabis-based products. Russo E, Agredano PM, Flachenecker P, Lawthom C, Munro D, Hindocha C, Bagul M, Trinka E. J Cannabis Res. 2024 Jul 24;6(1):32. doi: 10....

Umstrittene Internetplattformen: Cannabis so leicht wie Pizza ordern

11. August 2024 | Cannabis als Medizin

Umstrittene Internetplattformen: Cannabis so leicht wie Pizza ordern Seit der Legalisierung können Ärzte die Droge leichter verschreiben. Im Internet geht das sogar ohne Gespräch. Schwerkranke Patienten kritisieren das. (taz, 02.08.2024) h...

„Das ist ein absolutes No-Go“: Wie leichtfertig Internet-Ärzte Cannabis-Rezepte ausstellen

11. August 2024 | Cannabis als Medizin

„Das ist ein absolutes No-Go“: Wie leichtfertig Internet-Ärzte Cannabis-Rezepte ausstellen Medizinisches Gras boomt. Im Internet verschreiben Cannabis-Ärzte sehr leicht entsprechende Rezepte. Landesärztekammern sind alarmiert, ein Mediziner sieht...

Can you just cut back rather than stop cocaine use and have good outcomes?

11. August 2024 | Kokain

Can you just cut back rather than stop cocaine use and have good outcomes? For some individuals with substance use disorder, reducing alcohol and other drug use may confer some of the psychological and functional benefits also associated with sto...

MAPS Statement on FDA Complete Response Letter on MDMA-Assisted Therapy for PTSD New Drug Application

11. August 2024 | Amphetamine

MAPS Statement on FDA Complete Response Letter on MDMA-Assisted Therapy for PTSD New Drug Application San Jose, CA – The Multidisciplinary Association for Psychedelic Studies (MAPS) is evaluating the path forward for safe, legal access to MDMA-as...

Lykos Therapeutics Announces Complete Response Letter for Midomafetamine Capsules for PTSD

11. August 2024 | Amphetamine

Lykos Therapeutics Announces Complete Response Letter for Midomafetamine Capsules for PTSD U.S. Food and Drug Administration requests additional Phase 3 study Issues raised in CRL echo those discussed in FDA Advisory Committee hearing The Compa...

USA. FDA rejects MDMA as a psychedelic treatment for PTSD

11. August 2024 | Amphetamine

USA. FDA rejects MDMA as a psychedelic treatment for PTSD The Food and Drug Administration rejected MDMA as a treatment for post-traumatic stress disorder on Friday, in a blow to drug activists and veterans who’ve long campaigned for the psychede...

Efficacy and Safety of Modafinil for Treatment of Amphetamine-Type Stimulant Use Disorder: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials

11. August 2024 | Amphetamine

Efficacy and Safety of Modafinil for Treatment of Amphetamine-Type Stimulant Use Disorder: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials Efficacité et innocuité du modafinil pour le traitement des troubles liés à l...

Leo Sternbach and the benzodiazepines 60 years on: A revolutionary treatment for anxiety disorders.

11. August 2024 | Benzodiazepine

Leo Sternbach and the benzodiazepines 60 years on: A revolutionary treatment for anxiety disorders. Junkes L, Mendlowicz MV, Shader R, Nardi AE. Pharmacol Res. 2024 Jul 25;207:107310. doi: 10.1016/j.phrs.2024.107310. Epub ahead of pr...

Impact of the Ottawa model on opiate screening and smoking cessation in methadone-treated patients with opioid use disorder: A retrospective cohort analysis.

11. August 2024 | Nikotin

Impact of the Ottawa model on opiate screening and smoking cessation in methadone-treated patients with opioid use disorder: A retrospective cohort analysis. Lee SW, Yu PC, Yen TT, Hsu CY, Lai LJ, Chen IC, Chang TG. Tob Induc Dis. 20...

Fentanyl, carfentanil and other fentanyl analogues in Canada's illicit opioid supply: A cross-sectional study.

11. August 2024 | Fentanyl

Fentanyl, carfentanil and other fentanyl analogues in Canada's illicit opioid supply: A cross-sectional study. Kleinman RA. Drug Alcohol Depend Rep. 2024 May 23;12:100240. doi: 10.1016/j.dadr.2024.100240. PMID: 39035468; PMCID: PMC11...

Need for strategic communications and stakeholder engagement to advance acceptability of an overdose preventing vaccine targeting fentanyl.

11. August 2024 | Fentanyl

Need for strategic communications and stakeholder engagement to advance acceptability of an overdose preventing vaccine targeting fentanyl. Weitzman ER, Pierce SE, Blakemore LM, Murdock A, Angelidou A, Dowling DJ, Levy O, Levy S. Vac...

Fentanyl: Central Europe Sees Pockets of Rising Synthetic Opioid Use

11. August 2024 | Fentanyl

Fentanyl: Central Europe Sees Pockets of Rising Synthetic Opioid Use Nicholas Watson, Claudia Ciobanu, Peter Dlhopolec and Jules Eisenchteter (Bratislava, Prague, Warsaw), (BIRN, 24.07.2024) https://balkaninsight.com/2024/07/24/fentanyl-c...

Xylazine awareness, desire, use and exposure: Preliminary findings from the Rhode Island community-based drug checking cohort study.

11. August 2024 | Verschiedene

Xylazine awareness, desire, use and exposure: Preliminary findings from the Rhode Island community-based drug checking cohort study. Park JN, Serafinski R, Ujeneza M, McKenzie M, Tardif J, Krotulski AJ, Badea A, Grossman ER, Green TC. ...

Genehmigungsvorbehalt bei Cannabisverordnung entfällt für bestimmte Arztgruppen

25. Juli 2024 | Cannabis als Medizin

Genehmigungsvorbehalt bei Cannabisverordnung entfällt für bestimmte Arztgruppen Die Verpflichtung, vor einer Erstverordnung von medizinischem Cannabis eine Genehmigung der jeweiligen Krankenkasse einzuholen, entfällt künftig für verschiedene Arzt...

New analgesic could replace opioids over the long term

25. Juli 2024 | Opioide

New analgesic could replace opioids over the long term Researchers at Mainz University have identified a natural active substance that may prove to be an effective alternative to opioids in the long run and could also help mitigate the opioid cri...

Cocaine is being contaminated with powerful opioids called nitazenes. Here’s why it’s a dangerous mix

25. Juli 2024 | Opioide

Cocaine is being contaminated with powerful opioids called nitazenes. Here’s why it’s a dangerous mix Earlier this month, drugs sold as cocaine in Melbourne were found to be contaminated with a powerful group of opioids, known as ...

National and regional trends in fentanyl seizures in the United States, 2017-2023.

25. Juli 2024 | Fentanyl

National and regional trends in fentanyl seizures in the United States, 2017-2023. Palamar JJ, Fitzgerald N, Carr TH, Cottler LB, Ciccarone D. Int J Drug Policy. 2024 May 3:104417. doi: 10.1016/j.drugpo.2024.104417. Epub ahead of pri...

Your brain on shrooms — how psilocybin resets neural networks

25. Juli 2024 | Verschiedene

Your brain on shrooms — how psilocybin resets neural networks The psychedelic drug causes some lasting changes to the communication pathways that connect brain regions. Nature Nes, USA, 17.07.2024) https://www.nature.com/articles/d415...

Psilocybin desynchronizes the human brain.

25. Juli 2024 | Verschiedene

Psilocybin desynchronizes the human brain. Siegel, J.S., Subramanian, S., Perry, D. et al. Nature (2024). https://doi.org/10.1038/s41586-024-07624-5

Single-Dose Psilocybin Treatment for Major Depressive Disorder: A Randomized Clinical Trial.

25. Juli 2024 | Verschiedene

Single-Dose Psilocybin Treatment for Major Depressive Disorder: A Randomized Clinical Trial. Raison CL, Sanacora G, Woolley J, et al. JAMA. 2023;330(9):843–853. doi:10.1001/jama.2023.14530 https://jamanetwork.com...

USA. 'Emerging Threat' Xylazine Use Continues to Spread Across the United States

25. Juli 2024 | Verschiedene

USA. 'Emerging Threat' Xylazine Use Continues to Spread Across the United States Medscape - July 16, 2024. https://www.medscape.com/viewarticle/emerging-threat-xylazine-use-continues-spread-across-united-2024a1000d1h

USA. Xylazine Spreads West According to New Millennium Health Signals Alert™

25. Juli 2024 | Verschiedene

USA. Xylazine Spreads West According to New Millennium Health Signals Alert™ Urine drug test (UDT) data indicate significant uptick in xylazine use in the West, remains deeply entrenched in the East. (Millenium Health, USA, 16.07-2024) http...

USA. 'Pink Cocaine' Emerging as New Threat in Drug Market, Experts Warn

25. Juli 2024 | Neue Psychoaktive Substanzen

USA. 'Pink Cocaine' Emerging as New Threat in Drug Market, Experts Warn Pink is the new white – at least in the international, dynamic domain of synthetic drugs. A potent powder known among users and traffickers as "pink cocaine" is gaining trac...

Schweiz. Fentanyl - Informationen für Suchtfachpersonen & Einsatzkräfte - Faktenblatt

16. Juli 2024 | Fentanyl

Schweiz. Fentanyl - Informationen für Suchtfachpersonen & Einsatzkräfte - Faktenblatt Schweizerische Koordinations- und Fachstelle Sucht, Infodrog 2024, 2. aktualisierte Version https://www.infodrog.ch/files/content/factsheets/2024-06_infodr...

‘Oxymorphone Hydrochloride Tablets 40 mg’. Please see the attached photographs from the Finnish Police.

16. Juli 2024 | Opioide

Finnland. Seizure of 330 fake oxymorphone tablets containing metonitazene — Kouvola, Finland, May 2024 Dear Colleagues, Further to the advisory issued on Friday 12 June 2024 on the outbreak in Ireland linked to fake benzodiazepine tablets contai...

Neues Schmerzmittel könnte Opioide langfristig ersetzen

16. Juli 2024 | Opioide

Neues Schmerzmittel könnte Opioide langfristig ersetzen Forschende der JGU finden einen Naturwirkstoff, der Opioide langfristig ersetzen und die Opioidkrise mildern könnte. (IDW / Johannes Gutenberg-Universität Mainz, 11.07.2024) https://idw-onl...

BZgA. Faltblatt "Die Sucht und ihre Stoffe - Opiat- und Opioid-Schmerzmittel"

16. Juli 2024 | Opioide

BZgA. Faltblatt "Die Sucht und ihre Stoffe - Opiat- und Opioid-Schmerzmittel" BzGA – Bundeszentrale für gesundheitliche Aufklärung, 2020 https://shop.bzga.de/faltblatt-die-sucht-und-ihre-stoffe-opiat-und-opioid-schmerzmittel-34007002/

UNODC. Current NPS Threats - Volume VII - July 2024

16. Juli 2024 | Neue Psychoaktive Substanzen

UNODC. Current NPS Threats - Volume VII - July 2024 Over 1,200 individual NPS have been reported to the UNODC Early Warning Advisory on New Psychoactive Substances (NPS) by 142 countries and territories worldwide. Continuous prevalence of benzod...

Mexiko/USA. Mexiko: Fentanyl, neue Droge Nummer 1 (2023) ARTE Reportage

13. Juli 2024 | Fentanyl

Mexiko/USA. Mexiko: Fentanyl, neue Droge Nummer 1 (2023) ARTE Reportage Fentanyl, ein hochwirksames synthetisches Opioid aus dem Krankenhaus, verdrängte in den letzten Jahren viele andere Drogen in den USA, mit dramatischen Folgen. Synthetis...

Ketamin lindert Depression auch in Tablettenform

13. Juli 2024 | Verschiedene

Ketamin lindert Depression auch in Tablettenform Dunedin – Ketamin kann auch in Form von Tabletten die Symptome einer therapieresistenten Depression lindern und dies bei ausgezeichneter Verträglichkeit, wie Forschende aus Neuseeland im Fachblatt&...

Synthetische Opioide auf dem Vormarsch

09. Juli 2024 | Fentanyl

Synthetische Opioide auf dem Vormarsch Mit Sorge berichtete Joanna M. De Morais, Wissenschaftlerin vom „European Monitoring Centre for Drugs and Drug Addiction“ (EMCDDA) Ende Mai 2024 auf dem 44. Kongress der europäischen Giftzentren und Toxikolo...

Kratom as a potential substance use disorder harm reduction agent.

07. Juli 2024 | Verschiedene

Kratom as a potential substance use disorder harm reduction agent. Green M, Vadiei N, Veltri CA, Grundmann O, Evoy KE. Front Public Health. 2024 May 30;12:1416689. doi: 10.3389/fpubh.2024.1416689. PMID: 38873312; PMCID: PMC11169875. ...

Efficacy of e-health interventions for smoking cessation management in smokers: a systematic review and meta-analysis

06. Juli 2024 | Nikotin

Efficacy of e-health interventions for smoking cessation management in smokers: a systematic review and meta-analysis Li, Shen et al. eClinicalMedicine, Volume 68, 102412 https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)...

A. Risk of drug-related death associated with co-prescribing of gabapentinoids and Z-drugs among people receiving opioid-agonist treatment: A national retrospective cohort study.

06. Juli 2024 | Gabapentinoide

A. Risk of drug-related death associated with co-prescribing of gabapentinoids and Z-drugs among people receiving opioid-agonist treatment: A national retrospective cohort study. Glancy M, Palmateer N, Yeung A, Hickman M, Macleod J, Bishop ...

Pregabalin-induced rhabdomyolysis: a case series and literature analysis.

06. Juli 2024 | Gabapentinoide

Pregabalin-induced rhabdomyolysis: a case series and literature analysis. Zhai W, Liu H, Li J, Xin H. J Int Med Res. 2024 Jun;52(6):3000605241257776. doi: 10.1177/03000605241257776. PMID: 38879799; PMCID: PMC11181883. https://www.nc...

Gabapentin and Pregabalin Are Associated with Severe COPD Exacerbations

06. Juli 2024 | Gabapentinoide

Gabapentin and Pregabalin Are Associated with Severe COPD Exacerbations Daniel D. Dressler, MD, MSc, MHM, FACP, reviewing Rahman AA et al. Ann Intern Med 2024 Jan 16 NEJM Journal Watch, 25.01.2024 A study suggests yet another potential adverse ...

Das künstlich hergestellte Opioid "Fentanyl" ist unter Drogenabhängigen auf dem Vormarsch - Video

06. Juli 2024 | Fentanyl

Das künstlich hergestellte Opioid "Fentanyl" ist unter Drogenabhängigen auf dem Vormarsch - Video (NDR, tagesschau, 26.06.2024, 02:00) https://www.tagesschau.de/multimedia/video/video-1352616.html

Reported Xylazine Use Among Adults Aged ≥18 Years Evaluated for Substance Use Treatment - United States, July 2022-September 2023.

06. Juli 2024 | Verschiedene

The Complexities of Kratom: Insights on an Increasingly Frequent Clinical Encounter.

06. Juli 2024 | Verschiedene

The Complexities of Kratom: Insights on an Increasingly Frequent Clinical Encounter. Alghalith A, Nguyen H, Tennant R. Cureus. 2024 May 4;16(5):e59650. doi: 10.7759/cureus.59650. PMID: 38832209; PMCID: PMC11146460. https://www.ncbi....

Brain alterations in Cocaine Use Disorder: Does the route of use matter and does it relate to the treatment outcome?

06. Juli 2024 | Kokain

Brain alterations in Cocaine Use Disorder: Does the route of use matter and does it relate to the treatment outcome? Poireau M, Segobin S, Maillard A, Clergue-Duval V, Icick R, Azuar J, Volle E, Delmaire C, Bloch V, Pitel AL, Vorspan F.&nbs...

Characterization and Metabolism of Drug Products Containing the Cocaine-Like New Psychoactive Substances Indatraline and Troparil.

06. Juli 2024 | Kokain

Characterization and Metabolism of Drug Products Containing the Cocaine-Like New Psychoactive Substances Indatraline and Troparil. Manier SK, Mumber P, Zapp J, Eckstein N, Meyer MR. Metabolites. 2024 Jun 18;14(6):342. doi: 10.3390/me...

Structural brain changes associated with cocaine use and digital cognitive behavioral therapy in cocaine use disorder treatment.

06. Juli 2024 | Kokain

Structural brain changes associated with cocaine use and digital cognitive behavioral therapy in cocaine use disorder treatment. McCurdy LY, DeVito EE, Loya JM, Nich C, Zhai ZW, Kiluk BD, Potenza MN. Drug Alcohol Depend Rep. 2024 Jun...

Yin and Yang of Gut Microbiota in Cocaine Abuse.

06. Juli 2024 | Kokain

Yin and Yang of Gut Microbiota in Cocaine Abuse. Baldi S, Gerace E, Mannaioni G, Amedei A. Front Biosci (Landmark Ed). 2024 Jun 17;29(6):215. doi: 10.31083/j.fbl2906215. PMID: 38940056. https://www.imrpress.com/journal/FBL/29/6/10.3...

Cognitive functioning associated with acute and subacute effects of classic psychedelics and MDMA - a systematic review and meta-analysis.

06. Juli 2024 | Amphetamine

Cognitive functioning associated with acute and subacute effects of classic psychedelics and MDMA - a systematic review and meta-analysis. Basedow LA, Majić T, Hafiz NJ, Algharably EAE, Kreutz R, Riemer TG. Sci Rep. 2024 Jun 26;14(1)...

Structural basis of Δ9-THC analog activity at the Cannabinoid 1 receptor.

06. Juli 2024 | Cannabis als Medizin

Structural basis of Δ9-THC analog activity at the Cannabinoid 1 receptor. Gloriam D, Thorsen T, Kulkarni Y, Sykes D, Bøggild A, Drace T, Hompluem P, Iliopoulos-Tsoutsouvas C, Nikas S, Daver H, Makriyannis A, Nissen P, Gajhede M, Veprin...

Report of the Dutch State Committee on MDMA: A summary of findings and recommendations

04. Juli 2024 | Amphetamine

Report of the Dutch State Committee on MDMA: A summary of findings and recommendations Written by Wim van den Brink, Em Prof of Psychiatry and Addiction, Amsterdam University Medical Centers, Amsterdam, The Netherlands, Co-chair of the ...

Benzodiazepine use in relation to long-term dementia risk and imaging markers of neurodegeneration: a population-based study.

04. Juli 2024 | Benzodiazepine

Benzodiazepine use in relation to long-term dementia risk and imaging markers of neurodegeneration: a population-based study. Hofe, I.v., Stricker, B.H., Vernooij, M.W. et al. BMC Med 22, 266 (2024). doi.org/10.1186/s12916-024-03...

Kava (Piper Methysticum)

04. Juli 2024 | Verschiedene

Kava (Piper Methysticum) Themenseite bei Drug Science (UK) https://www.drugscience.org.uk/kava

Neue Daten aus Frankreich: Neurologische Schäden nach Konsum hoher Lachgas-Dosen, DGN plant Erhebung in Deutschland

04. Juli 2024 | Verschiedene

Neue Daten aus Frankreich: Neurologische Schäden nach Konsum hoher Lachgas-Dosen, DGN plant Erhebung in Deutschland Eine Studie aus dem Großraum Paris [1] zeigt den Anstieg schwerer Folgeerkrankungen durch den Freizeitkonsum von Lachgas (N2O) sei...

EUDA. EU Drug Market: New psychoactive substances — Distribution and supply in Europe: New opioids

02. Juli 2024 | Opioide

EUDA. EU Drug Market: New psychoactive substances — Distribution and supply in Europe: New opioids New opioids are sold as substances in their own right and as replacements for controlled opioids. They are also mis-sold as or used to adulterate h...

USA. 'Super Mario' street drug bags with compound 100 times stronger than fentanyl detected in this state

02. Juli 2024 | Fentanyl

USA. 'Super Mario' street drug bags with compound 100 times stronger than fentanyl detected in this state Other substances combined in the bags include fentanyl, a veterinary sedative called xylazine and heroin. A new street drug labeled "S...

West-Afrika. Kush: FTIR spectrometer testing indicates presence of synthetic cannabinoids and nitazenes in Freetown and Bissau

02. Juli 2024 | Fentanyl

West-Afrika. Kush: FTIR spectrometer testing indicates presence of synthetic cannabinoids and nitazenes in Freetown and Bissau In the absence of reliable chemical testing, ‘kush’ was suspected to include fentanyl, acetone, formaldehyde, tramadol,...

Two-Drug Combo Promising for Methamphetamine Use Disorder

02. Juli 2024 | Amphetamine

Two-Drug Combo Promising for Methamphetamine Use Disorder Extended-release injectable naltrexone combined with extended-release oral bupropion (NTX + BUPN) for moderate or severe methamphetamine use disorder was associated with a significant decr...

UNO warnt vor neuen synthetischen Drogen – Nitazene gefährlicher als Fentanyl

30. Juni 2024 | Fentanyl

UNO warnt vor neuen synthetischen Drogen – Nitazene gefährlicher als Fentanyl Wien – Die UNO warnt vor einer neuen Gruppe synthetischer Drogen, die noch gefährlicher sind als Fentanyl. Die sogenannten Nitazene, 500 Mal stärker als Morphin, seien ...

Bioisosteric analogs of MDMA: Improving the pharmacological profile?

30. Juni 2024 | Amphetamine

Bioisosteric analogs of MDMA: Improving the pharmacological profile? Alberto-Silva, A. S., Hemmer, S., Bock, H. A., da Silva, L. A., Scott, K. R., Kastner, N., Bhatt, M., Niell...

USA. FDA advisors voted against MDMA therapy – researchers are still fighting for it

30. Juni 2024 | Amphetamine

USA. FDA advisors voted against MDMA therapy – researchers are still fighting for it A vote against using MDMA as part of therapy for PTSD has provoked a powerful backlash among researchers who study psychedelic drugs. (BBC, UK, 20.6.2024) https...

Extended-release ketamine tablets for treatment-resistant depression: a randomized placebo-controlled phase 2 trial.

30. Juni 2024 | Verschiedene

Extended-release ketamine tablets for treatment-resistant depression: a randomized placebo-controlled phase 2 trial. Glue, P., Loo, C., Fam, J. et al. Nat Med (2024). doi.org/10.1038/s41591-024-03063-x https://www.nature.com/art...

USA/Kalifornien. Boba Fett, blue fish, and fettuccine: How L.A. fentanyl sales boomed on Craigslist

25. Juni 2024 | Fentanyl

USA/Kalifornien. Boba Fett, blue fish, and fettuccine: How L.A. fentanyl sales boomed on Craigslist At first glance, the items listed for sale on Craigslist seemed benign: Blue socks. A fancy china set. A collectible action figure. But there was...

An urgent need for community lot testing of lateral flow fentanyl test strips marketed for harm reduction in Northern America.

20. Juni 2024 | Fentanyl

An urgent need for community lot testing of lateral flow fentanyl test strips marketed for harm reduction in Northern America. Lieberman M, Badea A, Desnoyers C, Hayes K, Park JN. Harm Reduct J. 2024 Jun 15;21(1):115. doi: 10.1186/s1...

Kokainfo.de ist deine Plattform rund um Kokain.

19. Juni 2024 | Kokain

Kokainfo.de ist deine Plattform rund um Kokain. Hier findest du Informationen zur Wirkung und den Risiken von Kokain sowie verschiedene Selbst-Tests. Diese Tests sind anonym und geben dir einen Einblick in verschiedene Aspekte deines Konsum...

INVITATION TO JOIN THE INTERNATIONAL NETWORK FOR THE TREATMENT OF ALCOHOL USE DISORDER (INTAUT)

19. Juni 2024 | Alkohol

INVITATION TO JOIN THE INTERNATIONAL NETWORK FOR THE TREATMENT OF ALCOHOL USE DISORDER (INTAUT) Dear colleagues,We all have alcohol-dependent patients w...

UNODC. The challenge of New Psychoactive Substances – A technical update 2024

12. Juni 2024 | Neue Psychoaktive Substanzen

UNODC. The challenge of New Psychoactive Substances – A technical update 2024 The challenge of New Psychoactive Substances – A technical update 2024 is an update of the UNODC publication “The challenge of new psychoactive substances, 2013”, which...

Thilo Beck. Pharmakologische Ansätze bei problematischem Kokainkonsum (Präsentation, 10.06.2024)

11. Juni 2024 | Kokain

Thilo Beck. Pharmakologische Ansätze bei problematischem Kokainkonsum (Präsentation, 10.06.2024) Thilo Beck Co-Chefarzt Psychiatrie Arud 10.06.2024 Th. Beck. Pharmakologische Ansätze bei problematischem Kokainkonsum_10.06.2024...

Europäische Online-Befragung zum Thema Drogen EWSD 2024

09. Juni 2024 | Verschiedene

Europäische Online-Befragung zum Thema Drogen EWSD 2024 Die Europäische Online Drogenstudie (EWSD) ist eine webbasierte Erhebung, die Informationen über die Muster des Drogenkonsums in ganz Europa sammelt. Obwohl die EWSD nicht repräsentativ für ...

JES. Fentanyl - zwischen Fakten und Mythen unterscheiden

07. Juni 2024 | Fentanyl

JES. Fentanyl - zwischen Fakten und Mythen unterscheiden Kann Fentanyl über Hautkontakt übertragen werden? Hilft Naloxon auch bei einer Fentanyl-Überdosierung? Kann schon die Menge einer Bleistiftspitze Fentanyl tödlich sein? Wie kann man Risiken...

AkdÄ. Information zu Pregabalin und Gabapentin: Berichterstattung in den Medien zu Todesfällen

06. Juni 2024 | Gabapentinoide

AkdÄ. Information zu Pregabalin und Gabapentin: Berichterstattung in den Medien zu Todesfällen Die AkdÄ erreichen derzeit Anfragen zu Medienberichten über Todesfälle im Zusammenhang mit Pregabalin und Gabapentin (sog. „Gabapentinoide“). Diese bas...

Droge MDMA bei Belastungsstörung: US-Expertengremium rät davon ab

06. Juni 2024 | Amphetamine

Droge MDMA bei Belastungsstörung: US-Expertengremium rät davon ab Washington – Ein Expertengremium der US-Arzneimittelbehörde FDA lehnt eine neue Therapie gegen posttraumatische Belastungsstörung mit der auch als Ecstasy bekannten chemi...

Nal von Minden. Drug-Screen Fentanyl 10ng Teststreifen (Dose)

06. Juni 2024 | Fentanyl

Nal von Minden. Drug-Screen Fentanyl 10ng Teststreifen (Dose) 53,00 € zzgl. MwSt. https://nal-vonminden.com/deu/drug-screen-fyl-teststreifen-dose-cu10.html

Das Doppelgesicht von Fentanyl: Die neuronalen Grundlagen der Opioidabhängigkeit

06. Juni 2024 | Fentanyl

Das Doppelgesicht von Fentanyl: Die neuronalen Grundlagen der Opioidabhängigkeit Wissenschaftler der Universität Genf haben herausgefunden, dass Fentanyl zwei verschiedene Zellpopulationen im Gehirn aktiviert, und zwar sowohl bei der Einnahme als...

Fentanyl Exposure: Myths, Misconceptions, and the Media

06. Juni 2024 | Fentanyl

Fentanyl Exposure: Myths, Misconceptions, and the Media Author: Zach Siegel Contributors: Laura Bennett, Bella Horton, and Andrew Ian Stolbach 2023 The Center For Just Journalism, USA https://justjournalism.org/page/fentanyl-exposure

USA. MDMA therapy for PTSD rejected by FDA panel

05. Juni 2024 | Amphetamine

USA. MDMA therapy for PTSD rejected by FDA panel Scientific advisers vote overwhelmingly that the risks of MDMA treatment for post-traumatic stress disorder outweigh the benefits. (Nature, USA, 05.06.2024) https://www.nature.com/articles/d41586-...

Short-Acting, Full Agonist Opioids During Initiation of Opioid Agonist Treatment in the Fentanyl Era.

05. Juni 2024 | Fentanyl

Short-Acting, Full Agonist Opioids During Initiation of Opioid Agonist Treatment in the Fentanyl Era. Saxon AJ. JAMA Netw Open. 2024;7(5):e2411398. doi:10.1001/jamanetworkopen.2024.11398 https://jamanetwork.com/journals/jamanet...

Changes in injecting versus smoking heroin, fentanyl, and methamphetamine among people who inject drugs in San Diego, California, 2020-2023.

05. Juni 2024 | Fentanyl

Changes in injecting versus smoking heroin, fentanyl, and methamphetamine among people who inject drugs in San Diego, California, 2020-2023. Eger WH, Abramovitz D, Bazzi AR, Bórquez A, Vera CF, Harvey-Vera A, Friedman JR, Strathdee SA. ...

Innovation and adaptation: The rise of a fentanyl smoking culture in San Francisco.

05. Juni 2024 | Fentanyl

Innovation and adaptation: The rise of a fentanyl smoking culture in San Francisco. Ciccarone D, Holm N, Ondocsin J, Schlosser A, Fessel J, Cowan A, et al. (2024) PLoS ONE 19(5): e0303403. doi.org/10.1371/journal.pone.0303403 https:...

Extrem hohe Nikotindosen in tabakfreien Nikotinbeuteln

05. Juni 2024 | Nikotin

Extrem hohe Nikotindosen in tabakfreien Nikotinbeuteln Berlin/München – Tabakfreie Nikotinbeutel (Pouches) können hohe Nikotinmengen abgeben – einige Produkte übertreffen sogar Nikotindosen in Tabakzigaretten. Zu diesem Ergebnis kommen Forschend...

Canada's THC unit: Applications for the legal cannabis market.

05. Juni 2024 | Cannabis als Rauschmittel

Canada's THC unit: Applications for the legal cannabis market. Wood S, Gabrys R, Freeman T, Hammond D. Int J Drug Policy. 2024 May 20;128:104457. doi: 10.1016/j.drugpo.2024.104457. Epub ahead of print. PMID: 38772194. https://www.sc...

Medical cannabis use in Australia seven years after legalisation: findings from the online Cannabis as Medicine Survey 2022-2023 (CAMS-22).

05. Juni 2024 | Cannabis als Medizin

Medical cannabis use in Australia seven years after legalisation: findings from the online Cannabis as Medicine Survey 2022-2023 (CAMS-22). Mills L, Arnold JC, Suraev A, Abelev SV, Zhou C, Arkell TR, McGregor IS, Lintzeris N. Harm Reduct J...

Predictors of cocaine use disorder treatment outcomes: a systematic review.

05. Juni 2024 | Kokain

Predictors of cocaine use disorder treatment outcomes: a systematic review. Palazón-Llecha A, Caparrós B, Trujols J, Duran-Sindreu S, Batlle F, Madre M, Mallorquí-Bagué N. Syst Rev. 2024 May 8;13(1):124. doi: 10.1186/s13643-024-02550...

Risks of congenital malformations and neonatal intensive care unit admissions with gabapentin use in pregnancy: A cohort study and scoping review with meta-analysis.

05. Juni 2024 | Gabapentinoide

Risks of congenital malformations and neonatal intensive care unit admissions with gabapentin use in pregnancy: A cohort study and scoping review with meta-analysis. Desrochers B, Lavu A, Valencia E, Vaccaro C, Peymani P, Eltonsy S. ...

Xylazine: A Drug Adulterant of Clinical Concern.

05. Juni 2024 | Verschiedene

Xylazine: A Drug Adulterant of Clinical Concern. Edinoff AN, Sall S, Upshaw WC, Spillers NJ, Vincik LY, De Witt AS, Murnane KS, Kaye AM, Kaye AD. Curr Pain Headache Rep. 2024 May;28(5):417-426. doi: 10.1007/s11916-024-01211-z. Epub 2...

Was ist Lachgas und welche Folgen hat der Konsum?

05. Juni 2024 | Verschiedene

Was ist Lachgas und welche Folgen hat der Konsum? Lachgas wird für medizinische und industrielle Zwecke verwendet. In den letzten Jahren konsumieren es mehr Menschen als Droge. Es wirkt für einige Minuten euphorisierend und entspannend. Der häufi...

USA. Gangs mix another potent sedative into U.S. street drugs causing 'mass overdoses'

05. Juni 2024 | Verschiedene

USA. Gangs mix another potent sedative into U.S. street drugs causing 'mass overdoses' Public health officials say Mexican cartels and drug gangs inside the U.S. are mixing a dangerous chemical sedative called medetomidine into fentanyl and...

What Are Nitazines? Interview with Shayla Schlossenberg at the UN

05. Juni 2024 | Opioide

What Are Nitazines? Interview with Shayla Schlossenberg at the UN You have likely heard of a new group of synthetic substances, Nitazines, increasingly sold on illicit drug markets in North America and in Europe. We interviewed Shayla Schlossenbe...

The emergence of nitazenes on the Irish heroin market and national preparation for possible future outbreaks.

05. Juni 2024 | Opioide

The emergence of nitazenes on the Irish heroin market and national preparation for possible future outbreaks. Killeen, N., Lakes, R., Webster, M., Killoran, S., McNamara, S., Kavanagh, P., Eagleton, M., McCormack, S., Micheau, E., Moughty, ...

Schottland. Nitazenes: SDF Launch Alert and Information Resources for People at Risk of Overdose

05. Juni 2024 | Opioide

Schottland. Nitazenes: SDF Launch Alert and Information Resources for People at Risk of Overdose (SDF – Scottish Drugs Forum, 15.12.2023) https://sdf.org.uk/nitazenes-sdf-launch-alert-and-information-resources-for-people-at-risk-of-overdose/

USA. Philly health officials detect a veterinary sedative more powerful than xylazine in drug samples

29. Mai 2024 | Opioide

USA. Philly health officials detect a veterinary sedative more powerful than xylazine in drug samples A veterinary drug similar to xylazine, medetomidine, turned up in two samples of fentanyl in Philadelphia, and a Montgomery County residen...

Anteil Fentanyl-belasteter Heroinproben in ausgewählten Städten und Regionen in Deutschland im Jahr 2023

26. Mai 2024 | Fentanyl

Anteil Fentanyl-belasteter Heroinproben in ausgewählten Städten und Regionen in Deutschland im Jahr 2023 (Statista, 07.03.2024) https://de.statista.com/statistik/daten/studie/1455425/umfrage/fentanyl-belastete-proben-von-strassenheroin-in-...

Distinct µ-opioid ensembles trigger positive and negative fentanyl reinforcement.

26. Mai 2024 | Fentanyl

Distinct µ-opioid ensembles trigger positive and negative fentanyl reinforcement. Chaudun, F., Python, L., Liu, Y. et al. Nature (2024). https://doi.org/10.1038/s41586-024-07440-x https://www.nature.com/articles/s41586-024-07440-x

Neural pathways for reward and relief promote fentanyl addiction

26. Mai 2024 | Fentanyl

Neural pathways for reward and relief promote fentanyl addiction Neuroscientists find that two distinct neural pathways are responsible for the addictive properties of the opioid fentanyl: one mediates reward, the other promotes the seeking of re...

Dramatic increase in fentanyl seized by authorities in last six years

26. Mai 2024 | Fentanyl

Dramatic increase in fentanyl seized by authorities in last six years Nearly half of seizures in pill form last year. (EurekAlert!, American Association for the Advancement of Science (AAAS), USA, 13.05.2024) https://www.eurekalert.org/new...

Fentanyl (Gelbe Liste)

21. Mai 2024 | Fentanyl

Fentanyl (Gelbe Liste) Fentanyl gehört zu den Opioidanalgetika und wird vorrangig zur Therapie starker und chronischer Schmerzen sowie als Narkosemittel in der Anästhesie angewendet. (Gelbe Liste, Stand: 19.03.2024) https://www.gelbe-liste....

Fentanyl DrugFacts - What is fentanyl?

21. Mai 2024 | Fentanyl

Fentanyl DrugFacts - What is fentanyl? Fentanyl is a powerful synthetic opioid that is similar to morphine but is 50 to 100 times more potent. (NIH – National Institute on Drug Abuse, USA, Juni 2021) https://nida.nih.gov/publications/drugfa...

Fentanyl: Eine neue „Modedroge“?

21. Mai 2024 | Fentanyl

Fentanyl: Eine neue „Modedroge“? Dr. Wilhelm Unglaub, Dr. Beate Erbas, Professor Dr. Norbert Wodarz Bayerisches Ärzteblatt 1-2/2014 https://www.bayerisches-aerzteblatt.de/fileadmin/aerzteblatt/ausgaben/2014/01/einzelpdf/BAB_1_2_2014_46_47.pdf

EMCDDA. Fentanyl Drogenprofil

21. Mai 2024 | Fentanyl

EMCDDA. Fentanyl Drogenprofil Fentanyl ist ein narkotisierendes Analgetikum mit mindestens 80 mal höherer Wirkstärke als Morphin. Fentanyl und seine Derivative (Alfentanil, Sufentanil, Remifentanil und Carfentanil) werden sowohl in der Human- als...

The Fentanyl Story

21. Mai 2024 | Fentanyl

The Fentanyl Story Theodore H. Stanley, Department of Anesthesiology, School of Medicine, University of Utah, Salt Lake City, Utah. The Journal of Pain, Vol 15, No 12 (December), 2014: pp 1215-1226 https://www.jpain.org/article/S1526-5900(14)00...

USA. Fentanyl: Emergency Responders at Risk - Preventing Emergency Responders’ Exposures to Illicit Drugs

21. Mai 2024 | Fentanyl

USA. Fentanyl: Emergency Responders at Risk - Preventing Emergency Responders’ Exposures to Illicit Drugs Responders are likely to come into contact with a mixture of illicit drugs during routine job duties. These mixtures of illicit drugs can in...

Why Is Fentanyl Driving Overdose Deaths?

21. Mai 2024 | Fentanyl

Why Is Fentanyl Driving Overdose Deaths? A Yale Medicine addiction medicine specialist discusses how the synthetic opioid became a problem. (Yale Medicine, USA, 18.03.2024) https://www.yalemedicine.org/news/fentanyl-driving-overdoses

Fentanyl

21. Mai 2024 | Fentanyl

Fentanyl Fentanyl ist ein synthetisches Opioid, das als potentes Schmerzmittel in der Anästhesie (bei Narkosen) sowie als transdermales therapeutisches System zur Therapie von chronischen Schmerzzuständen, die nur mit Opiatanalgetika ausreichend ...

Australien. Powerful opioid fentanyl poses serious risk of fatal overdose

21. Mai 2024 | Fentanyl

Australien. Powerful opioid fentanyl poses serious risk of fatal overdose The death of Prince and the NSW Coroner’s comments on 13 deaths among injecting drug users in a month, suspected to be related to heroin has sparked media interest in fenta...

HOW TO TEST YOUR DRUGS USING FENTANYL TEST STRIPS

21. Mai 2024 | Fentanyl

HOW TO TEST YOUR DRUGS USING FENTANYL TEST STRIPS New York City Health, 2021 https://www.nyc.gov/assets/doh/downloads/pdf/basas/fentanyl-test-strips-brochure.pdf

EU-EWS. Formal notification of N,N-diethyl-2-[2-[[4-(2-fluoroethoxy)phenyl]methyl]-5-nitro-benzimidazol-1-yl]ethanamine (fluetonitazene) by Germany

15. Mai 2024 | Opioide

EU-EWS. Formal notification of N,N-diethyl-2-[2-[[4-(2-fluoroethoxy)phenyl]methyl]-5-nitro-benzimidazol-1-yl]ethanamine (fluetonitazene) by Germany EMCDDA, Lissabon, 14.05.2024 EU-EWS. Formal notification of N,N-diethyl-2-[2-[[4-(2-fluoroethoxy)...

UK. Synthetische Opioide - Mehr Fälle von Nitazen-Überdosierungen in Großbritannien

15. Mai 2024 | Opioide

UK. Synthetische Opioide - Mehr Fälle von Nitazen-Überdosierungen in Großbritannien Der missbräuchliche Einsatz des synthetischen Opioids Fentanyl führt zu vielen vermeidbaren Todesfällen. Nun mehren sich Berichte zu lebensbedrohlichen Vergiftung...

Schweiz. Ein Medikament beunruhigt Berner Behörden

13. Mai 2024 | Gabapentinoide

Schweiz. Ein Medikament beunruhigt Berner Behörden In Bern konsumieren Asylsuchende grosse Mengen des Schmerzmittels Pregabalin. Die Folgen: Die Polizei ist überfordert. (srf – Schweizerischer Rundfunk, Schweiz, 05.04.2024) https://www.srf...

USA. Over 115 million pills containing illicit fentanyl seized by law enforcement in 2023

13. Mai 2024 | Fentanyl

USA. Over 115 million pills containing illicit fentanyl seized by law enforcement in 2023 NIH-supported study highlights increasingly dangerous illicit drug supply, risk of pills not coming from a pharmacy. (NIH-NIDA, USA, 13.05.2024) http...

USA. National and regional trends in fentanyl seizures in the United States, 2017–2023

13. Mai 2024 | Fentanyl

USA. National and regional trends in fentanyl seizures in the United States, 2017–2023 Joseph J. Palamar, Nicole Fitzgerald, Daniel Ciccarone International Journal of Drug Policy, Available online 13 May 2024, 104417 https://www.sciencedirect.c...

Neue psychoaktive Substanzen (NpS)

06. Mai 2024 | Neue Psychoaktive Substanzen

Neue psychoaktive Substanzen (NpS) Gredner T, Gollrad T, Erbas B Bayerische Akademie für Suchtfragen in Forschung und Praxis BAS e.V., (2. überarbeitete u. ergänzte Auflage, Stand März 2023) https://www.bas-muenchen.de/wp-content/uploads/BAS_UG...

Fentanyl activates opposing opioid and non-opioid receptor systems that control breathing.

05. Mai 2024 | Fentanyl

Fentanyl activates opposing opioid and non-opioid receptor systems that control breathing. Baby SM, May WJ, Getsy PM, Coffee GA, Nakashe T, Bates JN, Levine A, Lewis SJ. Front Pharmacol. 2024 Apr 18;15:1381073. doi: 10.3389/fphar.202...

Mapping the Neural Substrates of Cocaine Craving: A Systematic Review.

05. Mai 2024 | Kokain

Mapping the Neural Substrates of Cocaine Craving: A Systematic Review. Paludetto LS, Florence LLA, Torales J, Ventriglio A, Castaldelli-Maia JM. Brain Sci. 2024 Mar 29;14(4):329. doi: 10.3390/brainsci14040329. PMID: 38671981; PMCID: ...

Snow season: The normalisation of cocaine.

05. Mai 2024 | Kokain

Snow season: The normalisation of cocaine. Hellman M. Nordisk Alkohol Nark. 2024 Apr;41(2):139-141. doi: 10.1177/14550725241234732. Epub 2024 Mar 18. PMID: 38645968; PMCID: PMC11027847. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1...

Synthetic Cathinones: Epidemiology, Toxicity, Potential for Abuse, and Current Public Health Perspective.

05. Mai 2024 | Verschiedene

Synthetic Cathinones: Epidemiology, Toxicity, Potential for Abuse, and Current Public Health Perspective. Chen S, Zhou W, Lai M. Brain Sci. 2024 Mar 29;14(4):334. doi: 10.3390/brainsci14040334. PMID: 38671986; PMCID: PMC11048581. https://...

Review of the Use of Medicinal Cannabis Products in Palliative Care.

05. Mai 2024 | Cannabis als Medizin

Review of the Use of Medicinal Cannabis Products in Palliative Care. Troyer J, Tanco K. Cancers (Basel). 2024 Apr 4;16(7):1412. doi: 10.3390/cancers16071412. PMID: 38611090; PMCID: PMC11011126. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11011...

The Use of Tetrahydrocannabinol Is Associated with an Increase in Survival Time in Palliative Cancer Patients: A Retrospective Multicenter Cohort Study.

05. Mai 2024 | Cannabis als Medizin

The Use of Tetrahydrocannabinol Is Associated with an Increase in Survival Time in Palliative Cancer Patients: A Retrospective Multicenter Cohort Study. Gastmeier K, Gastmeier A, Schwab F, Herdegen T. Med Cannabis Cannabinoids. 2024 Mar 1...

Phytocannabinoids: Exploring Pharmacological Profiles and Their Impact on Therapeutical Use.

05. Mai 2024 | Cannabis als Medizin

Phytocannabinoids: Exploring Pharmacological Profiles and Their Impact on Therapeutical Use. Blebea NM, Pricopie AI, Vlad RA, Hancu G. Int J Mol Sci. 2024 Apr 10;25(8):4204. doi: 10.3390/ijms25084204. PMID: 38673788; PMCID: PMC110505...

USA. Statement from DEA Administrator Anne Milgram on the Increase in DEA Fentanyl Seizures Containing Xylazine

04. Mai 2024 | Verschiedene

USA. Statement from DEA Administrator Anne Milgram on the Increase in DEA Fentanyl Seizures Containing Xylazine WASHINGTON – DEA first warned the public of a sharp increase in fentanyl seizures containing xylazine in our March 2023 Public Safety ...

Fentanyl and its derivatives: Pain-killers or man-killers?

04. Mai 2024 | Fentanyl

Fentanyl and its derivatives: Pain-killers or man-killers? Patocka J, Wu W, Oleksak P, Jelinkova R, Nepovimova E, Spicanova L, Springerova P, Alomar S, Long M, Kuca K. Heliyon. 2024 Mar 28;10(8):e28795. doi: 10.1016/j.heliyon.2024.e2...

Managing Opioid Withdrawal Symptoms During the Fentanyl Crisis: A Review.

04. Mai 2024 | Fentanyl

Managing Opioid Withdrawal Symptoms During the Fentanyl Crisis: A Review. Weber AN, Trebach J, Brenner MA, Thomas MM, Bormann NL. Subst Abuse Rehabil. 2024 Apr 10;15:59-71. doi: 10.2147/SAR.S433358. PMID: 38623317; PMCID: PMC11016949...

"Everything is kind of the same except my mind is with me": exploring cannabis substitution in a sample of adults in early recovery from an opioid or stimulant addiction.

04. Mai 2024 | Cannabis als Medizin

"Everything is kind of the same except my mind is with me": exploring cannabis substitution in a sample of adults in early recovery from an opioid or stimulant addiction. Beaugard CA, Walley AY, Amodeo M. Harm Reduct J. 2024 Apr 20;2...

Cannabis use, health problems, and criminal offences in Germany: national and state-level trends between 2009 and 2021.

04. Mai 2024 | Cannabis als Rauschmittel

Cannabis use, health problems, and criminal offences in Germany: national and state-level trends between 2009 and 2021. Manthey, J., Klinger, S., Rosenkranz, M. et al. Eur Arch Psychiatry Clin Neurosci (2024). doi.org/10.1007/s00...

DHS: Neuer DHS Flyer zum bewussten Umgang mit Cannabis

04. Mai 2024 | Cannabis als Rauschmittel

DHS: Neuer DHS Flyer zum bewussten Umgang mit Cannabis Ein jetzt erschienenes DHS Faltblatt informiert darüber, dass sich die Risiken des Cannabiskonsums durch bewusste Verhaltensweisen beim Konsum beeinflussen lassen. Die Hinweise richten sich a...

Heroin and other opioids – the current situation in Europe (European Drug Report 2023)

03. Mai 2024 | Opioide

Heroin and other opioids – the current situation in Europe (European Drug Report 2023) Heroin remains Europe’s most commonly used illicit opioid and is also the drug responsible for a large share of the health burden attributed to illicit d...

Prevalence and health consequences of nonmedical use of tramadol in Africa: A systematic scoping review.

03. Mai 2024 | Opioide

Prevalence and health consequences of nonmedical use of tramadol in Africa: A systematic scoping review. Boun SS, Omonaiye O, Yaya S. PLOS Glob Public Health. 2024 Jan 18;4(1):e0002784. doi: 10.1371/journal.pgph.0002784. PMID: 382368...

Presence of kratom in opioid overdose deaths: findings from coroner postmortem toxicological report.

03. Mai 2024 | Verschiedene

Presence of kratom in opioid overdose deaths: findings from coroner postmortem toxicological report. Torrico T, Patel K, Nikolov N, Salam MT, Padhy R, Weinstein D. Front Psychiatry. 2024 Jan 10;14:1332999. doi: 10.3389/fpsyt.2023.133...

An insight review on the neuropharmacological effects, mechanisms of action, pharmacokinetics and toxicity of mitragynine.

03. Mai 2024 | Verschiedene

An insight review on the neuropharmacological effects, mechanisms of action, pharmacokinetics and toxicity of mitragynine. Annuar NAK, Azlan UK, Mediani A, Tong X, Han R, Al-Olayan E, Baharum SN, Bunawan H, Sarian MN, Hamezah HS, Jantan I.&...

Fentanyl

03. Mai 2024 | Fentanyl

Fentanyl Fentanyl gehört zu den Opioidanalgetika und wird vorrangig zur Therapie starker und chronischer Schmerzen sowie als Narkosemittel in der Anästhesie angewendet. (Gelbe Liste, aufgerufen am 03.05.2024) https://www.gelbe-liste.de/wirkstoff...

USA. CDC-Themenseite zu Fentanyl

03. Mai 2024 | Fentanyl

USA. CDC-Themenseite zu Fentanyl Fentanyli s a synthetic opioid pain reliever. It is many times more powerful than other opioids and is approved for treating severe pain, typically advanced cancer pain1. Illegally made and distributed fentanyl ha...

Fentanyl: Warum es den Heroinkonsum in Europa ablösen wird und wie wir die Gefahr von Überdosen einschränken können

03. Mai 2024 | Fentanyl

Fentanyl: Warum es den Heroinkonsum in Europa ablösen wird und wie wir die Gefahr von Überdosen einschränken können Auf Europa rollt eine tödliche Fentanyl-Welle zu. Das Opioid, das 50-mal stärker ist als Heroin (und 100-mal stärker als Morphin),...

The Future of Fentanyl and Other Synthetic Opioids.

03. Mai 2024 | Fentanyl

The Future of Fentanyl and Other Synthetic Opioids. Pardo, Bryce, Jirka Taylor, Jonathan P. Caulkins, Beau Kilmer, Peter Reuter, and Bradley D. Stein, Santa Monica, CA: RAND Corporation, 2019. https://www.rand.org/pubs/researc...

Simplified guideline for prescribing medical cannabinoids in primary care.

03. Mai 2024 | Cannabis als Medizin

Simplified guideline for prescribing medical cannabinoids in primary care. Allan GM, Ramji J, Perry D, Ton J, Beahm NP, Crisp N, Dockrill B, Dubin RE, Findlay T, Kirkwood J, Fleming M, Makus K, Zhu X, Korownyk C, Kolber MR, McCormack J, Nic...

Partydrogen: Lachen bis die Ärztin kommt

21. April 2024 | Verschiedene

Partydrogen: Lachen bis die Ärztin kommt Dtsch Arztebl 2024; 121(8): A-521 / B-456 Es soll die Stimmung aufhellen, kann Halluzinationen auslösen und Glücksgefühle bis hin zur Euphorie hervorrufen: Lachgas erfreut sich in den vergangenen Jahren i...

Lachgas (N20): TRENDSPOTTER April 2024

19. April 2024 | Verschiedene

Lachgas (N20): TRENDSPOTTER April 2024 Dr. Heiko Bergmann, Regina Kühnl, Anna-Mavie Beil, Magdalena Janz & Franziska Schneider IFT Institut für Therapieforschung, München https://mindzone.info/wp-content/uploads/2024/04/NEWS-Trendspotter_La...

Ligand efficacy modulates conformational dynamics of the µ-opioid receptor.

19. April 2024 | Opioide

Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Zhao, J., Elgeti, M., O’Brien, E.S. et al. Nature (2024). doi.org/10.1038/s41586-024-07295-2 https://www.nature.com/articles/s41586-024-07295-2

Einblick in die molekularen Ursachen verschiedener Funktionen des Opioid-Rezeptors

19. April 2024 | Opioide

Einblick in die molekularen Ursachen verschiedener Funktionen des Opioid-Rezeptors Täglich sterben weltweit tausende Menschen an der Überdosierung von Opioiden wie Fentanyl. Medikamente, die auf den Opioid-Rezeptor wirken, haben teils heftige Neb...

UN Toolkit on Synthetic Drugs - ANNUAL SURVEY REPORT 2023

19. April 2024 | Verschiedene

UN Toolkit on Synthetic Drugs - ANNUAL SURVEY REPORT 2023 This report summarizes the key findings and insights gathered from the annual survey conducted of users of the UN Toolkit on Synthetic Drugs. The survey aimed to collect information on use...

Sierra Leone. Kush: Sierra Leone's new illegal drug

19. April 2024 | Verschiedene

Sierra Leone. Kush: Sierra Leone's new illegal drug This film contains upsetting scenes, drug use, and references to self-harm and suicide. Kush - a cheap new illegal drug, is ravaging communities in Sierra Leone. The BBC has heard r...

Sierra Leone. Sierra Leone declares emergency over drug kush - made from human bones

19. April 2024 | Verschiedene

Sierra Leone. Sierra Leone declares emergency over drug kush - made from human bones Sierra Leone's president has declared a national emergency over rampant drug abuse. Kush, a psychoactive blend of addictive substances, has been prevalent in th...

West-Afrika. Kush: what is this dangerous new west African drug that supposedly contains human bones?

19. April 2024 | Verschiedene

West-Afrika. Kush: what is this dangerous new west African drug that supposedly contains human bones? A new drug called kush is wreaking havoc in west Africa, particularly in Sierra Leone where it is estimated to kill around a dozen pe...

Factsheets der Schweizerischen Koordinations- und Fachstelle Sucht

19. April 2024 | Verschiedene

Factsheets der Schweizerischen Koordinations- und Fachstelle Sucht https://www.infodrog.ch/de/publikationen/faktenblaetter.html

Mitigating Risks from Human Xylazine Exposure - MEETING SUMMARY FEBRUARY 2024

19. April 2024 | Verschiedene

Mitigating Risks from Human Xylazine Exposure - MEETING SUMMARY FEBRUARY 2024 The Reagan-Udall Foundation for the FDA, in partnership with the U S Food and Drug Administration (FDA), held a hybrid public meeting titled “Mitigating Risks from Huma...

EUROPEAN PHARMACOPOEIA - Cannabis flower

19. April 2024 | Cannabis als Medizin

EUROPEAN PHARMACOPOEIA - Cannabis flower Published in accordance with the Convention on the Elaboration of a European Pharmacopoeia (European Treaty Series No. 50), The European Pharmacopoeia is published by the European Directorate for the Quali...

Bedrocan welcomes new European monograph for cannabis flowers

19. April 2024 | Cannabis als Medizin

Bedrocan welcomes new European monograph for cannabis flowers Europe has now the long-awaited quality standard monograph for cannabis flowers. The European Pharmacopoeia Commission officially published the monograph at the beginning of the year, ...

Cannabis and Cannabinoids in Adults With Cancer: ASCO Guideline.

19. April 2024 | Cannabis als Medizin

Cannabis and Cannabinoids in Adults With Cancer: ASCO Guideline. Ilana M. Braun et al. JCO 0, JCO.23.02596, DOI:10.1200/JCO.23.02596 https://ascopubs.org/doi/10.1200/JCO.23.02596

Keith Harring: Crack is Wack Mural

19. April 2024 | Kokain

Keith Harring: Crack is Wack Mural Crack Is Wack is a mural created in 1986 by American artist and social activist Keith Haring. Located near the Harlem River Drive in East Harlem, the mural serves as a warning against crack cocain...

Overdose from Unintentional Fentanyl Use when Intending to Use a Non-opioid Substance: An Analysis of Medically Attended Opioid Overdose Events.

07. April 2024 | Fentanyl

Overdose from Unintentional Fentanyl Use when Intending to Use a Non-opioid Substance: An Analysis of Medically Attended Opioid Overdose Events. Bazazi AR, Low P, Gomez BO, Snyder H, Hom JK, Soran CS, Zevin B, Mason M, Graterol J, Coffin PO...

Does cannabis use substitute for opioids? A preliminary exploratory survey in opioid maintenance patients.

06. April 2024 | Cannabis als Medizin

Does cannabis use substitute for opioids? A preliminary exploratory survey in opioid maintenance patients. Bekier NK, Frischknecht U, Eidenmueller K, Grimm F, Bach P, Stenger M, Kiefer F, Hermann D. Eur Arch Psychiatry Clin Neurosci....

The pharmacokinetics and pharmacodynamics of ibogaine in opioid use disorder patients.

06. April 2024 | Verschiedene

The pharmacokinetics and pharmacodynamics of ibogaine in opioid use disorder patients. Knuijver T, ter Heine R, Schellekens AFA, et al. Journal of Psychopharmacology. 2024;0(0). doi:10.1177/02698811241237873 https://journals.sagepub...

Association between benzodiazepine coprescription and mortality in people on opioid replacement therapy: a population-based cohort study.

06. April 2024 | Benzodiazepine

Association between benzodiazepine coprescription and mortality in people on opioid replacement therapy: a population-based cohort study. Best CS, Matheson C, Robertson J, Ritchie T, Cowden F, Dumbrell J, Duncan C, Kessavalou K, Woolston C,...

Factsheet: Lachgas

04. April 2024 | Verschiedene

Factsheet: Lachgas Lachgas ist die umgangssprachliche Bezeichnung für Distickstoffmonoxid (N2O), ein farb- und geruchloses, leicht süßlich schmeckendes Gas. Es gehört zur Gruppe der Stickoxide und ist sowohl zu technischen als auch zu medizinisc...

Pregabalin und Gabapentin in Kombination mit anderen Drogen – ein potenziell tödlicher Cocktail

03. April 2024 | Gabapentinoide

Pregabalin und Gabapentin in Kombination mit anderen Drogen – ein potenziell tödlicher Cocktail Die Suchtgefahr von Pregabalin ist bekannt. Aufgrund der entspannenden und euphorisierenden Wirkung wird Pregabalin (sowie auch Gabapentin) zunehmend ...

Death registrations related to Gabapentin or Pregabalin, England and Wales: 2018 and 2022.

03. April 2024 | Gabapentinoide

Death registrations related to Gabapentin or Pregabalin, England and Wales: 2018 and 2022. Office of National Statistics, UK, 24.01.2024 https://www.ons.gov.uk/file?uri=/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/adhocs/1...

Fentanyl abuse proportion in methadone maintenance treatment, and patients' knowledge about its risks.

03. April 2024 | Fentanyl

Fentanyl abuse proportion in methadone maintenance treatment, and patients' knowledge about its risks. Sason A, Adelson M, Schreiber S, Peles E. J Psychiatr Res. 2024 Mar 27;173:254-259. doi: 10.1016/j.jpsychires.2024.03.047. Epub ah...

Performance of Fentanyl Immunoassays in an ED Patient Population.

03. April 2024 | Fentanyl

Performance of Fentanyl Immunoassays in an ED Patient Population. Mills CM, Dryja PC, Champion-Lyons E, Keppler C, Babic N. J Appl Lab Med. 2024 Mar 22:jfae022. doi: 10.1093/jalm/jfae022. Epub ahead of print. PMID: 38517223. Ab...

Pharmacologic characterization of substituted nitazenes at mu, kappa and delta opioid receptors suggests high potential for toxicity.

03. April 2024 | Opioide

Pharmacologic characterization of substituted nitazenes at mu, kappa and delta opioid receptors suggests high potential for toxicity. Kozell LB, Eshleman AJ, Wolfrum KM, Swanson TL, Bloom SH, Benware S, Schmachtenberg JL, Schutzer KA, Schut...

Lachgas und Benzodiazepine Mediziner warnen vor aktuellen Trenddrogen

03. April 2024 | Verschiedene

Lachgas und Benzodiazepine Mediziner warnen vor aktuellen Trenddrogen Immer mehr Jugendliche konsumieren Lachgas und Beruhigungsmittel als Partydroge oder zum »Chillen«. Die teils frei erhältlichen Substanzen sind aber alles andere als harm...

Süchtig nach Ketamin: Ein ziemlich neues Leben

03. April 2024 | Verschiedene

Süchtig nach Ketamin: Ein ziemlich neues Leben Das Narkotikum Ketamin wird als Droge auf den Clubtoiletten gehandelt. Unser Autor war erst fasziniert, dann abhängig. Die Geschichte einer Rettung. (Die Tageszeitung, 31.03.2024) https://taz....

Ärzte warnen vor Nervenschäden durch Lachgas

26. März 2024 | Verschiedene

Ärzte warnen vor Nervenschäden durch Lachgas Konsum von vermeintlich harmlosem Lachgas. Auf die Inhalation des Narkosegases könnten schwere neurologische Beschwerden oder Blutbildstörungen folgen, erklärte die DGN kürzlich. (aerzteblatt.de,...

Effect of Cannabis Legalization in Canada on the Incidence of Psychosis Consultations in Quebec City's Psychiatric Emergency Services.

25. März 2024 | Cannabis als Rauschmittel

Effect of Cannabis Legalization in Canada on the Incidence of Psychosis Consultations in Quebec City's Psychiatric Emergency Services. L'Heureux S, Huot-Lavoie M, Bergeron A, Bergeron C, Blouin BP, Roy MA. Can J Psychiatry. 2024...

The prevalence of cannabis use disorders in people who use medicinal cannabis: A systematic review and meta-analysis.

25. März 2024 | Cannabis als Medizin

The prevalence of cannabis use disorders in people who use medicinal cannabis: A systematic review and meta-analysis. Dawson D, Stjepanović D, Lorenzetti V, Cheung C, Hall W, Leung J. Drug Alcohol Depend. 2024 Mar 8;257:111263. doi: ...

Synthetische Opioide. Mehr Fälle von Nitazen-Überdosierungen in Großbritannien

25. März 2024 | Opioide

Synthetische Opioide. Mehr Fälle von Nitazen-Überdosierungen in Großbritannien Der missbräuchliche Einsatz des synthetischen Opioids Fentanyl führt zu vielen vermeidbaren Todesfällen. Nun mehren sich Berichte zu lebensbedrohlichen Vergiftungen ei...

Lachgas als Droge auf der Reeperbahn

25. März 2024 | Verschiedene

Lachgas als Droge auf der Reeperbahn Auf der Reeperbahn saugen junge Besucher und Besucherinnen am Wochenende oft an schwarzen Luftballons – ein verbreitetes Bild auf St. Pauli. Sie inhalierten Lachgas, das für einen kurzzeitigen Rausch sorgt. Di...

Lachgas – ein Narkotikum.

25. März 2024 | Verschiedene

Lachgas – ein Narkotikum. Wagner, J.B., Wanke, E.M., Ohlendorf, D. et al. Zbl Arbeitsmed (2024). doi.org/10.1007/s40664-024-00531-6 https://link.springer.com/article/10.1007/s40664-024-00531-6

„Uns läuft die Zeit davon“ - Auch in Köln ist die „Zombie-Droge“ Fentanyl auf dem Vormarsch

25. März 2024 | Fentanyl

„Uns läuft die Zeit davon“ - Auch in Köln ist die „Zombie-Droge“ Fentanyl auf dem Vormarsch Noch gibt es wenige Fälle, doch Experten schätzen, dass Fentanyl bald in Köln zu mehr Drogennotfällen führen kann. Auch die Stadt bereitet sich vor. (Köln...

Setting the Record Straight on Long-Term Use, Dose Escalation, and Potential Misuse of Prescription Benzodiazepines.

25. März 2024 | Benzodiazepine

Setting the Record Straight on Long-Term Use, Dose Escalation, and Potential Misuse of Prescription Benzodiazepines. Soumerai SB, Shahzad M, Salzman C. Am J Psychiatry. 2024 Mar 1;181(3):186-188. doi: 10.1176/appi.ajp.20240030. ...

Schweiz. Therapieformen bei Crack- und Kokainkonsum - Bericht 2023

07. März 2024 | Kokain

Schweiz. Therapieformen bei Crack- und Kokainkonsum - Bericht 2023 Auftraggeberin: Bundesamt für Gesundheit BAG, Schwarzenburgstr. 157, 3003 Bern Auftragnehmerin: Schweizerische Gesellschaft für Suchtmedizin SSAM, Altenburgstr. 29, 3000 Bern 8 ...

Mortality and health-related quality of life in older adults with long-term use of opioids, z-hypnotics or benzodiazepines: a prospective observational study at 5 years follow-up.

07. März 2024 | Benzodiazepine

Mortality and health-related quality of life in older adults with long-term use of opioids, z-hypnotics or benzodiazepines: a prospective observational study at 5 years follow-up. Bjelkarøy MT, Simonsen TB, Siddiqui TG, Cheng S, Grambaite R...

Systematic review on intentional non-medical fentanyl use among people who use drugs.

07. März 2024 | Fentanyl

Systematic review on intentional non-medical fentanyl use among people who use drugs. Tsang VWL, Wong JSH, Westenberg JN, Ramadhan NH, Fadakar H, Nikoo M, Li VW, Mathew N, Azar P, Jang KL, Krausz RM. Front Psychiatry. 2024 Feb 13;15:...

New Drug Trends: Insights from Focus Group Discussions. Civil Society

07. März 2024 | Verschiedene

New Drug Trends: Insights from Focus Group Discussions. Civil Society Van der Gouwe, D. et al. (2024). Monitoring of Harm Reduction in Europe 2023. Amsterdam, Correlation – European Harm Reduction Network. ISBN: 9789083391519 https://www.c...

Phenibut—an Illegal Food Supplement With Psychotropic Effects and Health Risks.

07. März 2024 | Verschiedene

Phenibut—an Illegal Food Supplement With Psychotropic Effects and Health Risks. Bonnet U, Scherbaum N, Schaper A, Soyka M. Dtsch Arztebl Int. 2024 Apr 5;(Forthcoming):arztebl.m2024.0003. doi: 10.3238/arztebl.m2024.0003. Epub ahead of print....

Cannabis and Anxiety: A Critical Review.

07. März 2024 | Cannabis als Rauschmittel

Cannabis and Anxiety: A Critical Review. Beletsky A, Liu C, Lochte B, Samuel N, Grant I. Med Cannabis Cannabinoids. 2024 Feb 23;7(1):19-30. doi: 10.1159/000534855. PMID: 38406383; PMCID: PMC10890807. https://www.ncbi.nlm.nih.gov/pmc...

Recreational Marijuana Legalization and Workplace Injuries Among Younger Workers.

07. März 2024 | Cannabis als Rauschmittel

Recreational Marijuana Legalization and Workplace Injuries Among Younger Workers. Li L, Liang Y, Sabia JJ, Dave DM. JAMA Health Forum. 2024 Feb 2;5(2):e235438. doi: 10.1001/jamahealthforum.2023.5438. PMID: 38393722; PMCID: PMC1089147...

What Does a Systematic Review of Cannabis and PTSD Tell Us? That We Need to Learn More.

07. März 2024 | Cannabis als Medizin

What Does a Systematic Review of Cannabis and PTSD Tell Us? That We Need to Learn More. Ostacher MJ. J Clin Psychiatry. 2024 Feb 14;85(1):23com15279. doi: 10.4088/JCP.23com15279. PMID: 38353646. https://www.psychiatrist.com/jcp...

N-desethyl isotonitazene detected in polydrug users admitted to hospital in Birmingham, United Kingdom.

07. März 2024 | Opioide

N-desethyl isotonitazene detected in polydrug users admitted to hospital in Birmingham, United Kingdom. Pucci M, Singh Jutley G, Looms J, Ford L. Clin Toxicol (Phila). 2024 Jan;62(1):19-25. doi: 10.1080/15563650.2024.2309321. Epub 20...

The Cytotoxic Effects of Nyaope, a Heroin-based Street Drug, in SH-SY5Y Neuroblastoma Cells.

07. März 2024 | Opioide

The Cytotoxic Effects of Nyaope, a Heroin-based Street Drug, in SH-SY5Y Neuroblastoma Cells. Daniels WMU, Sekhotha MM, Morgan N, Manilall A. IBRO Neurosci Rep. 2024 Feb 7;16:280-290. doi: 10.1016/j.ibneur.2024.01.014. PMID:...

Non-fatal overdose with a new synthetic opioid.

07. März 2024 | Opioide

Non-fatal overdose with a new synthetic opioid. Stangeland M, Lunde T, Fossan KO, Berg JA. Tidsskr Nor Laegeforen. 2024 Jan 25;144(2). English, Norwegian. doi: 10.4045/tidsskr.23.0464. PMID: 38349109. https://tidsskriftet.no/en/2024...

Nitazenes represent a growing threat to public health in Europe

07. März 2024 | Opioide

Nitazenes represent a growing threat to public health in Europe Giraudon, Isabelle et al. The Lancet Public Health, Volume 0, Issue 0 https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(24)00024-0/fulltexthttps://www.thelancet...

Wastewater-based monitoring of the nitazene analogues: First detection of protonitazene in wastewater.

07. März 2024 | Opioide

Wastewater-based monitoring of the nitazene analogues: First detection of protonitazene in wastewater. Bade R, Nadarajan D, Driver EM, Halden RU, Gerber C, Krotulski A, Hall W, Mueller JF. Sci Total Environ. 2024 Apr 10;920:170781. d...

aerzteblatt.de: Nachrichten zu Cannabis

07. März 2024 | Cannabis als Rauschmittel

aerzteblatt.de: Nachrichten zu Cannabis https://www.aerzteblatt.de/nachrichten/sw/Cannabis

Fentanyl-Schnelltest: Das solltest du wissen

28. Februar 2024 | Fentanyl

Fentanyl-Schnelltest: Das solltest du wissen Das Faltblatt richtet sich an Heroinkonsument*innen, die in ihrer Drogenhilfeeinrichtung einen Schnelltest bekommen haben, um ihr Heroin zuhause bzw. außerhalb der Einrichtung auf die Beimengung von Fe...

USA. 'Gas station heroin' recalled over tianeptine: Supplement sent multiple people to hospital

28. Februar 2024 | Verschiedene

USA. 'Gas station heroin' recalled over tianeptine: Supplement sent multiple people to hospital A supplement dubbed "gas station heroin" has been linked to severe illnesses and was recalled because it contains an antidepressant not approved for m...

Sterberisiko steigt nach Absetzen von Benzodiazepinen – Experte betont Bedeutung der ärztlich begleiteten Entgiftung

28. Februar 2024 | Benzodiazepine

Sterberisiko steigt nach Absetzen von Benzodiazepinen – Experte betont Bedeutung der ärztlich begleiteten Entgiftung Medscape - 1. Feb 2024. https://deutsch.medscape.com/artikelansicht/4913385

Chronische Depressionen: medizinisches Cannabis zeigt Effekte

28. Februar 2024 | Cannabis als Medizin

Chronische Depressionen: medizinisches Cannabis zeigt Effekte Essen – Menschen mit chronischen Depressionen können von einer 6-wöchigen Therapie mit medizinischem Cannabis profitieren. In einer Pilotstudie halbierte sich der Schweregrad der Depre...

Weltweit tödlichste Droge in München aufgetaucht

28. Februar 2024 | Fentanyl

Weltweit tödlichste Droge in München aufgetaucht München – In München ist bei einer Polizeikontrolle das als weltweit tödlichste Droge geltende Carfentanyl aufgetaucht. (aerzteblatt.de, 12.02.2024) https://www.aerzteblatt.de/nachrichten/149227/W...

USA. THE SILENT EPIDEMIC - FENTANYL AND OLDER AMERICANS

28. Februar 2024 | Fentanyl

USA. THE SILENT EPIDEMIC - FENTANYL AND OLDER AMERICANS Findings Fentanyl and other synthetic opioids have devastated communities all over the United States, fueling the worst drug crisis in American history. While fentanyl is the leading cause...

Handreichung: Angebote für Crack-Konsument*innen in der Drogenhilfe

28. Februar 2024 | Kokain

Handreichung: Angebote für Crack-Konsument*innen in der Drogenhilfe Wie können Einrichtungen der Aids- und Drogenhilfe ihre Angebote an die Bedarfe von Crack-Konsument*innen anpassen? Eine Handreichung der Deutschen Aidshilfe (DAH) trägt einfach ...

Bundesmodellprojekt RaFT: Ergebnisse

21. Februar 2024 | Fentanyl

Bundesmodellprojekt RaFT: Ergebnisse Ein halbes Jahr lang wurden im Rahmen des Bundesmodellprojektes RaFT der Deutschen Aidshilfe in Drogenkonsumräumen Schnelltests auf die lebensgefährliche Beimengung von Fentanyl in Heroin angeboten, um die Ver...

Opioide: Fentanyl und Co. sind in Deutschland angekommen

21. Februar 2024 | Fentanyl

Opioide: Fentanyl und Co. sind in Deutschland angekommen Bundesmodellprojekt RaFT der Deutschen Aidshilfe weist synthetische Opioide als gefährliche Beimengung in Heroin nach. Bundesländer und Kommunen müssen jetzt vorsorgen und Drogenhilfe stärk...

Sicherstellung der extrem gefährlichen Droge Carfentanyl in München

16. Februar 2024 | Fentanyl

Sicherstellung der extrem gefährlichen Droge Carfentanyl in München Bereits im Dezember 2023 kam es zu einer Kontrolle von zwei Personen in einer Parkanlage des Münchner Stadtteils Bogenhausen durch Beamte der Polizeiinspektion 22. Bei eine...

BZgA .infos-cannabis.de - Informationskampagne des Bundesministeriums für Gesundheit (BMG)

16. Februar 2024 | Cannabis als Rauschmittel

BZgA .infos-cannabis.de - Informationskampagne des Bundesministeriums für Gesundheit (BMG) Mit der Kampagne „Cannabis: Legal, aber...“ möchte das Bundesministerium für Gesundheit (BMG) besonders junge Menschen dazu motivieren, sich über die psych...

Development of an anxiety disorder following an emergency department visit due to cannabis use: a population-based cohort study

12. Februar 2024 | Cannabis als Rauschmittel

Development of an anxiety disorder following an emergency department visit due to cannabis use: a population-based cohort study Myran, Daniel T. et al. eClinicalMedicine, Volume 0, Issue 0, 102455 https://www.thelancet.com/journals/eclinm...

Xylazine in the illicit opioid supply

10. Februar 2024 | Verschiedene

Xylazine in the illicit opioid supply Peter E. Wu MD MSc, Emily Austin MD CMAJ 2024 February 5;196:E133. doi: 10.1503/cmaj.231603 https://www.cmaj.ca/content/cmaj/196/4/E133.full.pdf

Animal Tranquilizer Xylazine Increasingly Found in Canada's Illegal Drug Supply

10. Februar 2024 | Verschiedene

Animal Tranquilizer Xylazine Increasingly Found in Canada's Illegal Drug Supply Medscape - February 09, 2024. https://www.medscape.com/viewarticle/animal-tranquilizer-xylazine-increasingly-found-canadas-2024a10002vp

Interview mit Medizinerin Dr. Evelyn Roth zum Thema Kokain - sauberdrauf! Podcast-Folge 13

10. Februar 2024 | Kokain

Interview mit Medizinerin Dr. Evelyn Roth zum Thema Kokain - sauberdrauf! Podcast-Folge 13 In der 13. Folge des MINDZONE-Podcasts spricht Patrick mit Dr. Evelyn Roth. Sie ist angehende Fachärztin im Bereich Psychiatrie und Psychotherapie und arbe...

Geschichte und Herstellung des Kokains und die Darstellung seines Konsums in den Texten deutscher Schriftsteller: ein intergenerationaler Vergleich am Beispiel von Walter Rheiner und Benjamin von Stuckrad-Barre.

10. Februar 2024 | Kokain

Geschichte und Herstellung des Kokains und die Darstellung seines Konsums in den Texten deutscher Schriftsteller: ein intergenerationaler Vergleich am Beispiel von Walter Rheiner und Benjamin von Stuckrad-Barre. Roth, Evelyn (2023 Open Acc...

Cannabis for Psychiatric Disorders? 'Not Today,' Experts Say

10. Februar 2024 | Cannabis als Medizin

Cannabis for Psychiatric Disorders? 'Not Today,' Experts Say Stephen M. Strakowski, Leslie A. Hulvershorn, Christopher J. Hammond. Medscape - Jan 08, 2024. https://www.medscape.com/viewarticle/997689

Cannabis vaporisation: Understanding products, devices and risks.

10. Februar 2024 | Cannabis als Medizin

Cannabis vaporisation: Understanding products, devices and risks. MacCallum CA, Lo LA, Pistawka CA, Christiansen A, Boivin M. Drug Alcohol Rev. 2023. doi.org/10.1111/dar.13800 https://onlinelibrary.wiley.com...

Kush: what is this dangerous new west African drug that supposedly contains human bones?

10. Februar 2024 | Verschiedene

Kush: what is this dangerous new west African drug that supposedly contains human bones? A new drug called kush is wreaking havoc in west Africa, particularly in Sierra Leone where it is estimated to kill around a dozen people each week and ...

Harnessing tobacco harm reduction

07. Februar 2024 | Nikotin

Harnessing tobacco harm reduction Beaglehole, Robert et al. The Lancet, Volume 0, Issue 0 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00140-5/fulltexthttps://www.thelancet.com/journals/lancet/article/PIIS0140-6736(2...

Heroin Toxicity.

04. Februar 2024 | Opioide

Heroin Toxicity. Oelhaf RC, Azadfard M., 2023 May 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 28613487. https://www.ncbi.nlm.nih.gov/books/NBK430736/

Heroin.

04. Februar 2024 | Opioide

Heroin. Huecker MR, Koutsothanasis GA, Abbasy MSU, Marraffa J. 2024 Jan 14. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 28722906. https://www.ncbi.nlm.nih.gov/books/NBK441876/

Opioid Use Disorder.

04. Februar 2024 | Opioide

Opioid Use Disorder. Dydyk AM, Jain NK, Gupta M. 2023 Jul 21. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 31985959. https://www.ncbi.nlm.nih.gov/books/NBK553166/

Opioid Toxicity.

04. Februar 2024 | Opioide

Opioid Toxicity. Oelhaf RC, Del Pozo E, Azadfard M., 2023 Jul 21. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 28613731. https://www.ncbi.nlm.nih.gov/books/NBK431077/

Opioid Receptor.

04. Februar 2024 | Opioide

Opioid Receptor. Dhaliwal A, Gupta M. Physiology, 2023 Jul 24. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 31536249. https://www.ncbi.nlm.nih.gov/books/NBK546642/

Trends in co-prescribed opioids and benzodiazepines, non-prescribed opioids and benzodiazepines, and schedule-I drugs in the United States, 2013 to 2019.

04. Februar 2024 | Benzodiazepine

Trends in co-prescribed opioids and benzodiazepines, non-prescribed opioids and benzodiazepines, and schedule-I drugs in the United States, 2013 to 2019. Taha SA, Westra JR, Tacker DH, Raji MA, Kuo YF. Prev Med Rep. 2023 Dec 29;38:10...

Effects of MDMA-assisted therapy for PTSD on self-experience.

04. Februar 2024 | Amphetamine

Effects of MDMA-assisted therapy for PTSD on self-experience. van der Kolk BA, Wang JB, Yehuda R, Bedrosian L, Coker AR, Harrison C, et al. (2024) PLoS ONE 19(1): e0295926. doi.org/10.1371/journal.pone.0295926 https://journals....

Neue Psychoaktive Substanzen in der Notfallmedizin [New psychoactive substances in emergency medicine].

04. Februar 2024 | Neue Psychoaktive Substanzen

Neue Psychoaktive Substanzen in der Notfallmedizin [New psychoactive substances in emergency medicine]. Marinowitz R, Strube J, Schaper A. Nervenarzt. 2024 Jan;95(1):28-34. German. doi: 10.1007/s00115-023-01602-4. Epub 2024 Jan 8. PM...

The impact of cannabis on non-medical opioid use among individuals receiving pharmacotherapies for opioid use disorder: a systematic review and meta-analysis of longitudinal studies.

04. Februar 2024 | Cannabis als Rauschmittel

The impact of cannabis on non-medical opioid use among individuals receiving pharmacotherapies for opioid use disorder: a systematic review and meta-analysis of longitudinal studies. Costa GPA, Nunes JC, Heringer DL, Anand A, De Aquino JP.&...

Cannabis Use Disorder.

04. Februar 2024 | Cannabis als Rauschmittel

Cannabis Use Disorder. Patel J, Marwaha R., 2022 Jul 11. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 30844158. https://www.ncbi.nlm.nih.gov/books/NBK538131/

Rauchstopp: E-Zigaretten in Vergleichsstudie gleich gut wirksam wie Vareniclin

04. Februar 2024 | Nikotin

Rauchstopp: E-Zigaretten in Vergleichsstudie gleich gut wirksam wie Vareniclin Peking – E-Zigaretten haben Raucher in einer größeren randomisierten Studie aus China fast doppelt so häufig zum Verzicht auf das Tabakrauchen verholfen wie ein medizi...

Effectiveness of Medical Cannabis for the Treatment of Depression: A Naturalistic Outpatient Study.

04. Februar 2024 | Cannabis als Medizin

Effectiveness of Medical Cannabis for the Treatment of Depression: A Naturalistic Outpatient Study. Specka M, Bonnet U, Schmidberg L, Wichmann J, Keller M, Scholze C, Scherbaum N. Pharmacopsychiatry. 2024 Jan 11. doi: 10.1055/a-2215-...

Cannabis verschlechtert Fahrleistung von Senioren im Straßenverkehr

04. Februar 2024 | Cannabis als Medizin

Cannabis verschlechtert Fahrleistung von Senioren im Straßenverkehr Toronto – Der Konsum von Cannabis vermindert die Fahrtüchtigkeit auch bei älteren Menschen, selbst wenn diese, wie die Teilnehmer einer Studie eine langjährige Erfahrung mit der ...

Cannabis and Driving in Older Adults.

04. Februar 2024 | Cannabis als Medizin

Cannabis and Driving in Older Adults. Di Ciano P, Rajji TK, Hong L, et al. JAMA Netw Open. 2024;7(1):e2352233. doi:10.1001/jamanetworkopen.2023.52233 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2814053

Cannabinoids in Treating Chemotherapy-Induced Nausea and Vomiting, Cancer-Associated Pain, and Tumor Growth.

04. Februar 2024 | Cannabis als Medizin

Cannabinoids in Treating Chemotherapy-Induced Nausea and Vomiting, Cancer-Associated Pain, and Tumor Growth. Bathula PP, Maciver MB. Int J Mol Sci. 2023 Dec 20;25(1):74. doi: 10.3390/ijms25010074. PMID: 38203245; PMCID: PMC10779013. ...

Overview: Chronic Pain and Cannabis-Based Medicines.

04. Februar 2024 | Cannabis als Medizin

Overview: Chronic Pain and Cannabis-Based Medicines. Karst M. Pharmacopsychiatry. 2024 Jan 10. doi: 10.1055/a-2231-6630. Epub ahead of print. PMID: 38198809. https://www.thieme-connect.com/products/ejournals/pdf/10.1055/a-2231-6630.pdf

Brain oxygen responses induced by opioids: focus on heroin, fentanyl, and their adulterants.

04. Februar 2024 | Fentanyl

Brain oxygen responses induced by opioids: focus on heroin, fentanyl, and their adulterants. Kiyatkin EA, Choi S. Front Psychiatry. 2024 Jan 17;15:1354722. doi: 10.3389/fpsyt.2024.1354722. PMID: 38299188; PMCID: PMC10828032. https:/...

Brain oxygen responses induced by opioids: focus on heroin, fentanyl, and their adulterants.

04. Februar 2024 | Opioide

Opioid Withdrawal.

04. Februar 2024 | Opioide

Opioid Withdrawal. Shah M, Huecker MR., 2023 Jul 21. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 30252268. https://www.ncbi.nlm.nih.gov/books/NBK526012/

Recreational and Medical Cannabis Legalization and Opioid Prescriptions and Mortality.

30. Januar 2024 | Cannabis als Rauschmittel

Recreational and Medical Cannabis Legalization and Opioid Prescriptions and Mortality. Nguyen HV, McGinty EE, Mital S, Alexander GC. JAMA Health Forum. 2024;5(1):e234897. doi:10.1001/jamahealthforum.2023.4897 https://j...

Recreational and Medical Cannabis Legalization and Opioid Prescriptions and Mortality.

30. Januar 2024 | Cannabis als Medizin

Cannabisgebrauch in Deutschland - Häufigkeit, Administrationswege und gemeinsame Nutzung von inhalierten Nikotin- und Tabakprodukten

30. Januar 2024 | Cannabis als Rauschmittel

Cannabisgebrauch in Deutschland - Häufigkeit, Administrationswege und gemeinsame Nutzung von inhalierten Nikotin- und Tabakprodukten Cannabis use in Germany: Frequency, routes of administration, and co-use of inhaled nicotine or tobacco products ...

Efficacy of Electronic Cigarettes vs Varenicline and Nicotine Chewing Gum as an Aid to Stop Smoking: A Randomized Clinical Trial.

30. Januar 2024 | Nikotin

Efficacy of Electronic Cigarettes vs Varenicline and Nicotine Chewing Gum as an Aid to Stop Smoking: A Randomized Clinical Trial. Lin H, Liu Z, Hajek P, et al. JAMA Intern Med. Published online January 29, 2024. d...

Update to Gabapentinoid Use in the United States, 2002-2021

25. Januar 2024 | Gabapentinoide

Update to Gabapentinoid Use in the United States, 2002-2021 Michael E. Johansen, Donovan T. Maust The Annals of Family Medicine Jan 2024, 22 (1) 45-49; DOI: 10.1370/afm.3052 https://www.annfammed.org/content/22/1/45

The impact of cannabis on non-medical opioid use among individuals receiving pharmacotherapies for opioid use disorder: a systematic review and meta-analysis of longitudinal studies,

25. Januar 2024 | Cannabis als Medizin

The Therapeutic Potential of Cannabidiol in Revolutionising Opioid Use Disorder Management.

25. Januar 2024 | Cannabis als Medizin

The Therapeutic Potential of Cannabidiol in Revolutionising Opioid Use Disorder Management. Le K, Au J, Hua J, Le KDR. Cureus. 2023 Dec 16;15(12):e50634. doi: 10.7759/cureus.50634. PMID: 38226097; PMCID: PMC10789504. https://www.ncb...

Dosing of Cannabinoids Associated with an Opioid-Sparing Effect: A Systematic Review of Longitudinal Studies

25. Januar 2024 | Cannabis als Medizin

Dosing of Cannabinoids Associated with an Opioid-Sparing Effect: A Systematic Review of Longitudinal Studies El-Mourad, Jihane et al. Pain Management Nursing, Volume 25, Issue 1, e8 - e20 https://www.painmanagementnursing.org/article/S152...

Zahl Alkoholabhängiger leicht gestiegen

25. Januar 2024 | Alkohol

Zahl Alkoholabhängiger leicht gestiegen Berlin – Die Zahl nachweislich alkoholabhängiger Menschen in Deutschland ist leicht angestiegen. Im Jahr 2022 wurden 1.058.000 Männer und 467.000 Frauen in Deutschland mit Alkoholsucht ambulant oder station...

Schottland. New opioids and benzos in Scotland’s drugs supply (Webinar)

25. Januar 2024 | Opioide

Schottland. New opioids and benzos in Scotland’s drugs supply (Webinar) New opioids and benzos in Scotland’s drugs supply – Why we are concerned and what we need to do. (SDF – Scottish Drugs Forum, UK, 21.12.2023, Video, 59:03) https://www.youtu...

Medizinisches Cannabis könnte zu Herzrhythmusstörungen führen

21. Januar 2024 | Cannabis als Medizin

Medizinisches Cannabis könnte zu Herzrhythmusstörungen führen Kopenhagen – Dänische Patienten, denen zur Schmerzbehandlung medizinisches Cannabis verschrieben wurde, erkrankten in den folgenden 6 Monaten doppelt so häufig an Herzrhythmusstörungen...

Nitazenes: SDF Launch Alert and Information Resources for People at Risk of Overdose

21. Januar 2024 | Opioide

Nitazenes: SDF Launch Alert and Information Resources for People at Risk of Overdose Scottish Drugs Forum has worked with service providers and other stakeholders to develop information resources for people at risk of overdose due to the introduc...

ON ALERT: New opioids and benzos in Scotland’s drugs supply – Why we are concerned and what we need to do - (SDF Webinar)

21. Januar 2024 | Opioide

ON ALERT: New opioids and benzos in Scotland’s drugs supply – Why we are concerned and what we need to do - (SDF Webinar) (SDF - Scottish Drugs Forum, Webinar, 20.12.2023, 59:03) https://www.youtube.com/watch?app=desktop&v=eSDNPaW4qQ4

Nitazenes—heralding a second wave for the UK drug-related death crisis?

21. Januar 2024 | Opioide

Nitazenes—heralding a second wave for the UK drug-related death crisis? Holland, Adam et al. The Lancet Public Health, Volume 0, Issue 0 https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(24)00001-X/fulltexthttps://www.thelan...

Colombo Plan Health Alert: Injectable Liquid Fentanyl

21. Januar 2024 | Fentanyl

Colombo Plan Health Alert: Injectable Liquid Fentanyl Public safety and public health officials worldwide should be aware of an emerging threat of diverted liquid pharmaceutical fentanyl, and other liquid forms. This threat could have sever...

Tabakentwöhnung bei schwerer Tabakabhängigkeit: Nutzen für zwei von vier Wirkstoffen belegt

21. Januar 2024 | Nikotin

Tabakentwöhnung bei schwerer Tabakabhängigkeit: Nutzen für zwei von vier Wirkstoffen belegt Vareniclin und Nicotin bieten zur Tabakentwöhnung deutliche Vorteile für schwer abhängige Raucherinnen und Raucher. Entsprechende Nachweise für Bupropion ...

Psychedelics in Addiction Treatment—Navigating a Sociopolitical Rift.

21. Januar 2024 | Verschiedene

Psychedelics in Addiction Treatment—Navigating a Sociopolitical Rift. Mehtani NJ, Anderson BT, Mitchell JM. JAMA Neurol. Published online January 16, 2024. doi:10.1001/jamaneurol.2023.5173 Abstract https://jamanetwor...

Wie Ketamin, Scopolamin und Psilocybin Depressionen lindern

21. Januar 2024 | Verschiedene

Wie Ketamin, Scopolamin und Psilocybin Depressionen lindern Bristol – Die ungewöhnlich schnelle und über Wochen anhaltende Linderung von Depressionen, zu denen es unter der Behandlung mit Ketamin, Scopolamin und Psilocybin kommt, sind nach tierex...

Prescription opioid use among people with opioid dependence and concurrent benzodiazepine and gabapentinoid exposure: An analysis of overdose and all-cause mortality. (2)

08. Januar 2024 | Benzodiazepine

Prescription opioid use among people with opioid dependence and concurrent benzodiazepine and gabapentinoid exposure: An analysis of overdose and all-cause mortality. Bharat C, Gisev N, Barbieri S, Dobbins T, Larney S, Buizen L, Degenhardt ...

Examining predictors of cocaine withdrawal syndrome at the end of detoxification treatment in women with cocaine use disorder.

08. Januar 2024 | Kokain

Examining predictors of cocaine withdrawal syndrome at the end of detoxification treatment in women with cocaine use disorder. Heberle BA, Kluwe-Schiavon B, Bicca C, Melo Rothmann L, Grassi-Oliveira R, Viola TW. J Psychiatr Res. 2023...

Gabapentinoids: a therapeutic review.

08. Januar 2024 | Gabapentinoide

Gabapentinoids: a therapeutic review. Athavale A, Murnion B. Aust Prescr. 2023 Dec;46(4):80-85. doi: 10.18773/austprescr.2023.025. PMID: 38152314; PMCID: PMC10751078. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10751078/

A systematic evidence map of the association between cannabis use and psychosis-related outcomes across the psychosis continuum: An umbrella review of systematic reviews and meta-analyses.

08. Januar 2024 | Cannabis als Rauschmittel

A systematic evidence map of the association between cannabis use and psychosis-related outcomes across the psychosis continuum: An umbrella review of systematic reviews and meta-analyses. Groening JM, Denton E, Parvaiz R, Brunet DL, Von Da...

Adverse outcomes of cannabis use in Canada, before and after legalisation of non-medical cannabis: cross-sectional analysis of the International Cannabis Policy Study.

08. Januar 2024 | Cannabis als Rauschmittel

Adverse outcomes of cannabis use in Canada, before and after legalisation of non-medical cannabis: cross-sectional analysis of the International Cannabis Policy Study. Marquette A, Iraniparast M, Hammond D. BMJ Open. 2024 Jan 3;14(1)...

Perceptions of fentanyl among African Americans who misuse opioids: implications for risk reduction.

08. Januar 2024 | Fentanyl

Perceptions of fentanyl among African Americans who misuse opioids: implications for risk reduction. Rigg KK, Kusiak ES. Harm Reduct J. 2023 Dec 19;20(1):179. doi: 10.1186/s12954-023-00915-6. PMID: 38110965; PMCID: PMC10729467. http...

Cannabis as a Source of Approved Drugs: A New Look at an Old Problem.

08. Januar 2024 | Cannabis als Medizin

Cannabis as a Source of Approved Drugs: A New Look at an Old Problem. Gabarin A, Yarmolinsky L, Budovsky A, Khalfin B, Ben-Shabat S. Molecules. 2023 Nov 21;28(23):7686. doi: 10.3390/molecules28237686. PMID: 38067416; PMCID: PMC107075...

Cannabis for medical use versus opioids for chronic non-cancer pain: a systematic review and network meta-analysis of randomised clinical trials.

08. Januar 2024 | Cannabis als Medizin

Cannabis for medical use versus opioids for chronic non-cancer pain: a systematic review and network meta-analysis of randomised clinical trials. Jeddi HM, Busse JW, Sadeghirad B, Levine M, Zoratti MJ, Wang L, Noori A, Couban RJ, Tarride JE...

High-Cost and High-Dose Prescriptions of Cannabis-Based Medicines.

08. Januar 2024 | Cannabis als Medizin

High-Cost and High-Dose Prescriptions of Cannabis-Based Medicines. Hennig B, Schmidt-Wolf G, Cristinziani A, Cremer-Schaeffer P, Marschall U, Petzke F, Häuser W. Dtsch Arztebl Int. 2023 Nov 24;120(47):813-814. doi: 10.3238/arztebl.m2...

Hochkosten- beziehungsweise Hochdosisverschreibungen von cannabisbasierten Arzneimitteln - Ein Vergleich der Daten der BARMER und des Bundesinstituts für Arzneimittel und Medizinprodukte (BfArM)

08. Januar 2024 | Cannabis als Medizin

Hochkosten- beziehungsweise Hochdosisverschreibungen von cannabisbasierten Arzneimitteln - Ein Vergleich der Daten der BARMER und des Bundesinstituts für Arzneimittel und Medizinprodukte (BfArM) High-cost and high-dose prescriptions of canna...

Mindfulness and clinical correlates in methamphetamine use disorder.

08. Januar 2024 | Amphetamine

Mindfulness and clinical correlates in methamphetamine use disorder. Jarrett O, London ED, Mahmoudie T, Suh J, Ghahremani D, Dean AC. Drug Alcohol Depend. 2023 Dec 1;253:111029. doi: 10.1016/j.drugalcdep.2023.111029. Epub 2023 Nov 18...

Zürich. Depressions-Behandlung: erste klinische Anwendung von Psilocybin

05. Januar 2024 | Verschiedene

Zürich. Depressions-Behandlung: erste klinische Anwendung von Psilocybin Die Psychiatrische Universitätsklinik Zürich bietet als erste Universitätsklinik weltweit Psilocybin-assistierte Therapien für Erwachsene mit einer schwer zu behandelnden De...

Single-dose psilocybin-assisted therapy in major depressive disorder: a placebo-controlled, double-blind, randomised clinical trial

05. Januar 2024 | Verschiedene

Single-dose psilocybin-assisted therapy in major depressive disorder: a placebo-controlled, double-blind, randomised clinical trial von Rotz, Robin et al. eClinicalMedicine, Volume 56, 101809 https://www.thelancet.com/journals/eclinm/arti...

Anabolika

05. Januar 2024 | Verschiedene

Anabolika Themenseite von infodrog.ch und Schweizerische Koordinations- und Fachstelle Sucht https://www.infodrog.ch/de/wissen/suchtformen/anabolika.html

Medical Marijuana for Pain Management in Hospice Care as a Complementary Approach to Scheduled Opioids: A Single Arm Study.

01. Januar 2024 | Cannabis als Medizin

Medical Marijuana for Pain Management in Hospice Care as a Complementary Approach to Scheduled Opioids: A Single Arm Study. Zanker T, Sacco J, Prota J, Palma M, Viola Lee KA, Wang RR, Liang Y, Cunningham J, Mackary M, Ovchinnikova P. ...

Psilocybin lindert in Studie Depressionen bei Krebspatienten

01. Januar 2024 | Verschiedene

Psilocybin lindert in Studie Depressionen bei Krebspatienten Rockville – Die einmalige Einnahme des Psychedelikums Psilocybin hat in einer offenen Studie bei jedem 2. Krebspatienten mit Major Depression eine komplette Remission erzielt, die bei 3...

Orales Naltrexon und Acamprosat bieten die beste Chance bei Alkoholkrankheit

01. Januar 2024 | Alkohol

Orales Naltrexon und Acamprosat bieten die beste Chance bei Alkoholkrankheit Chapel Hill – Die Ergebnisse einer Metaanalyse von mehr als 100 Studien sprechen dafür, zur pharmakologischen Behandlung der Alkoholabhängigkeit in der Erstlinie orales...

Cannabis use disorder and adverse cardiovascular outcomes: A population-based retrospective cohort analysis of adults from Alberta, Canada.

23. Dezember 2023 | Cannabis als Rauschmittel

Cannabis use disorder and adverse cardiovascular outcomes: A population-based retrospective cohort analysis of adults from Alberta, Canada. Bahji A, Hathaway J, Adams D, Crockford D, Edelman EJ, Stein MD, et al.&nbs...

Not all kratom is equal: The important distinction between native leaf and extract products.

23. Dezember 2023 | Verschiedene

Not all kratom is equal: The important distinction between native leaf and extract products. Grundmann, O., Garcia-Romeu, A., McCurdy, C.R., Sharma, A., Smith, K.E., Swogger, M.T. and Weiss, S.T. (2024), Addiction, 119: 202-203. ...

Benzodiazepine Discontinuation and Mortality Among Patients Receiving Long-Term Benzodiazepine Therapy.

23. Dezember 2023 | Benzodiazepine

Benzodiazepine Discontinuation and Mortality Among Patients Receiving Long-Term Benzodiazepine Therapy. Maust DT, Petzold K, Strominger J, Kim HM, Bohnert ASB. JAMA Netw Open. 2023;6(12):e2348557. doi:10.1001...

Cannabis-Related Disorders and Toxic Effects.

17. Dezember 2023 | Cannabis als Rauschmittel

Cannabis-Related Disorders and Toxic Effects. Gorelick DA. N Engl J Med. 2023 Dec 14;389(24):2267-2275. doi: 10.1056/NEJMra2212152. PMID: 38091532. https://www.nejm.org/doi/pdf/10.1056/NEJMra2212152

NRW. Wandel der Konsummuster - Veränderungen in der Drogenszene – Konsequenzen für das Hilfesystem

17. Dezember 2023 | Kokain

NRW. Wandel der Konsummuster - Veränderungen in der Drogenszene – Konsequenzen für das Hilfesystem Dokumentation des Fachtages der Suchtkooperation Nordrhein-Westfalen am 10.05.2023 https://suchtkooperation.nrw/fileadmin/user_upload/Doku_final.pdf

Crack breitet sich aus: Höllisch high

17. Dezember 2023 | Kokain

Crack breitet sich aus: Höllisch high Immer mehr Menschen rauchen Crack. Das hat drastische Folgen für Konsumierende und Sozialarbeiter:innen. (Die Tageszeitung, 04.12.2023) https://taz.de/Crack-breitet-sich-aus/!5973785/

Schweiz. Crack – Themenschwerpunkt des Bundesamtes für Gesundheit

17. Dezember 2023 | Kokain

Schweiz. Crack – Themenschwerpunkt des Bundesamtes für Gesundheit Crack ist eine Mischung aus Kokainsalz und Natron, die mit kleinen Pfeifen geraucht wird. Crack ist zur Zeit leicht verfügbar und daher günstig, hat ein hohes Suchtpotenzial ...

UN Toolkit on Synthetic Drugs > Resource Library - Empowering Responses to the Global Synthetic Drug Problem, One Resource at a Time

17. Dezember 2023 | Verschiedene

UN Toolkit on Synthetic Drugs > Resource Library - Empowering Responses to the Global Synthetic Drug Problem, One Resource at a Time The Resource Library is a centralized hub for all the resources featured in the UN Toolkit on Synthetic Drugs....

Lachgas

17. Dezember 2023 | Verschiedene

Lachgas Lachgas wird auf Grund seiner psychotropen Eigenschaften („auf die Psyche einwirkend“) missbräuchlich als Rauschmittel eingesetzt. Höhere (missbräuchliche) Dosierungen erzeugen einen kurz anhaltenden euphorisierenden Effekt. Sekunden nach...

Verantwortungsbewusster Umgang Medikamente (Flyer, Podcast, Beratung)

17. Dezember 2023 | Verschiedene

Verantwortungsbewusster Umgang Medikamente (Flyer, Podcast, Beratung) Medikamente oder Arzneimittel sind Stoffe, die vom Arzt zur Heilung, Linderung von Beschwerden oder zur Verhütung von Krankheiten verschrieben werden. Wie alle Substanzen...

Fentanyl im Straßenheroin?

17. Dezember 2023 | Fentanyl

Fentanyl im Straßenheroin? Seit dem 1. März können Opiatgebraucher*innen in 17 Konsumräumen (in Berlin, Düsseldorf, Frankfurt, Hamburg, Hannover, Münster und Wuppertal) ihr Heroin auf Beimengung des gefährlichen Opioids Fentanyl testen lassen.3. ...

Arzneimittelinteraktionen von Tetrahydrocannabinol und Cannabidiol in cannabinoiden Arzneimitteln - Empfehlungen für die Praxis - Drug interactions of tetrahydrocannabinol and cannabidiol in cannabinoid drugs: recommendations for clinical practice.

17. Dezember 2023 | Cannabis als Medizin

Arzneimittelinteraktionen von Tetrahydrocannabinol und Cannabidiol in cannabinoiden Arzneimitteln - Empfehlungen für die Praxis - Drug interactions of tetrahydrocannabinol and cannabidiol in cannabinoid drugs: recommendations for clinical practice...

Medizinalcannabis: Freiheit für mehr Therapieoptionen

17. Dezember 2023 | Cannabis als Medizin

Medizinalcannabis: Freiheit für mehr Therapieoptionen Dtsch Arztebl 2023; 120(49): A-2072 / B-1760 Lau, Tobias Die Ampelkoalition will die Herstellung von Medizinalcannabis in Deutschland liberalisieren. Der staatlich beauftragte Anbau soll dur...

Verordnung von Cannabis in Arzneimittel-Richtlinie geregelt

06. Dezember 2023 | Cannabis als Medizin

Verordnung von Cannabis in Arzneimittel-Richtlinie geregelt 06.07.2023 - Die geänderte Arzneimittel-Richtlinie hinsichtlich der Verordnung von medizinischem Cannabis auf Kassenrezept ist am 30. Juni in Kraft getreten und ab sofort zu beachten. De...

The impact of cannabis legalization and decriminalization on acute poisoning: A systematic review.

06. Dezember 2023 | Cannabis als Rauschmittel

The impact of cannabis legalization and decriminalization on acute poisoning: A systematic review. Allaf, S, Lim, JS, Buckley, NA, Cairns, R. Addiction. 2023. doi.org/10.1111/add.16280 https://onlinelibrary.wiley.com/doi/10.1111/add...

The Appearance of Xylazine in the United States as a Fentanyl Adulterant.

06. Dezember 2023 | Verschiedene

The Appearance of Xylazine in the United States as a Fentanyl Adulterant. Leconte CE, Sethi R. Prim Care Companion CNS Disord. 2023 Oct 31;25(6):22nr03473. doi: 10.4088/PCC.22nr03473. PMID: 37923548. https://www.psychiatrist.com/pcc...

Massive genetic study finds genes linked to cannabis addiction

06. Dezember 2023 | Cannabis als Rauschmittel

Massive genetic study finds genes linked to cannabis addiction Data from more than one million genomes offer fresh insights into excessive cannabis use and its relationship to other diseases. (Nature, 20.11.2023) https://www.nature.com/articles/...

Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications.

06. Dezember 2023 | Cannabis als Rauschmittel

Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications. Levey, D.F., Galimberti, M., Deak, J.D. et al. Nat Genet (2023). doi.org/10.1038/s41588-023...

Kokain Check: Neuer Selbsttest zum Kokainkonsum

06. Dezember 2023 | Kokain

Kokain Check: Neuer Selbsttest zum Kokainkonsum Kokain ist ein starkes Aufputschmittel mit hohem Abhängigkeitspotential. Aber nicht alle Konsumentinnen und Konsumenten sind gleichermaßen betroffen. Mit Hilfe des neuen Selbsttests „Kokain Check“ k...

A Semi-Naturalistic, Open-Label Trial Examining the Effect of Prescribed Medical Cannabis on Neurocognitive Performance.

06. Dezember 2023 | Cannabis als Medizin

A Semi-Naturalistic, Open-Label Trial Examining the Effect of Prescribed Medical Cannabis on Neurocognitive Performance. Arkell TR, Manning B, Downey LA, Hayley AC. CNS Drugs. 2023 Nov;37(11):981-992. doi: 10.1007/s40263-023-01046-z....

The impact of a restricted pregabalin prescription policy on drug utilization: An observational multicenter study.

06. Dezember 2023 | Gabapentinoide

The impact of a restricted pregabalin prescription policy on drug utilization: An observational multicenter study. Al-Jedai A, Alkofide H, Almohimeed L, Alsalim L, Alruwaili A, Alissa DA, Almudaiheem H. Saudi Pharm J. 2023 Dec;31(12)...

Delirium following pregabalin discontinuation in an individual with no psychiatric or substance use history.

06. Dezember 2023 | Gabapentinoide

Delirium following pregabalin discontinuation in an individual with no psychiatric or substance use history. Awasthi H, Vohra A. BMJ Case Rep. 2023 Nov 17;16(11):e258104. doi: 10.1136/bcr-2023-258104. PMID: 37977830; PMCID: PMC106601...

Development of an intervention to manage benzodiazepine dependence and high-risk use in the context of escalating drug related deaths in Scotland: an application of the MRC framework.

06. Dezember 2023 | Benzodiazepine

Development of an intervention to manage benzodiazepine dependence and high-risk use in the context of escalating drug related deaths in Scotland: an application of the MRC framework. Berry K, Matheson C, Schofield J, Dumbrell J, Parkes T, ...

Stimulant and hallucinogenic novel psychoactive substances; an update.

06. Dezember 2023 | Neue Psychoaktive Substanzen

Stimulant and hallucinogenic novel psychoactive substances; an update. Schifano F, Vento A, Scherbaum N, Guirguis A. Expert Rev Clin Pharmacol. 2023 Jul-Dec;16(11):1109-1123. doi: 10.1080/17512433.2023.2279192. Epub 2023 Nov 22. PMID...

The in vitro functional profiles of fentanyl and nitazene analogs at the µ-opioid receptor - high efficacy is dangerous regardless of signaling bias.

06. Dezember 2023 | Fentanyl

The in vitro functional profiles of fentanyl and nitazene analogs at the µ-opioid receptor - high efficacy is dangerous regardless of signaling bias. Tsai MM, Chen L, Baumann MH, Canals M, Javitch JA, Lane JR, Shi L. bioRxi...

Does occupational exposure to fentanyl cause illness? A systematic review,

06. Dezember 2023 | Fentanyl

Does occupational exposure to fentanyl cause illness? A systematic review, Axel Adams, Caitlin Maloy & Brandon J. Warrick (2023) Clinical Toxicology, 61:9, 631-638, DOI: 10.1080/15563650.2023...

An Opioid Hiding in Plain Sight: Loperamide-Induced False-Positive Fentanyl and Buprenorphine Immunoassay Results,

06. Dezember 2023 | Fentanyl

An Opioid Hiding in Plain Sight: Loperamide-Induced False-Positive Fentanyl and Buprenorphine Immunoassay Results, K Aaron Geno, Adina Badea, Kara L Lynch, Paul Jannetto, Jacqueline A Hubbard, Robert D Nerenz, Mark A Cervinski, The J...

The emerging fentanyl–xylazine syndemic in the USA: challenges and future directions

06. Dezember 2023 | Fentanyl

The emerging fentanyl–xylazine syndemic in the USA: challenges and future directions Zhu, David T et al. The Lancet, Volume 402, Issue 10416, 1949 - 1952 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01686-0/fulltexth...

The opioid receptor: emergence through millennia of pharmaceutical sciences.

06. Dezember 2023 | Opioide

The opioid receptor: emergence through millennia of pharmaceutical sciences. Fairbanks CA, Peterson CD. Front Pain Res (Lausanne). 2023 Nov 1;4:960389. doi: 10.3389/fpain.2023.960389. PMID: 38028425; PMCID: PMC10646403. https://www....

Prevalence of energy drink consumption world-wide: A systematic review and meta-analysis.

06. Dezember 2023 | Verschiedene

Prevalence of energy drink consumption world-wide: A systematic review and meta-analysis. Aonso-Diego, G, Krotter, A, García-Pérez, Á. Addiction. 2023. doi.org/10.1111/add.16390 https://onlinelibrary.wiley.com/d...

Does nitrous oxide addiction exist? An evaluation of the evidence for the presence and prevalence of substance use disorder symptoms in recreational nitrous oxide users.

06. Dezember 2023 | Verschiedene

Does nitrous oxide addiction exist? An evaluation of the evidence for the presence and prevalence of substance use disorder symptoms in recreational nitrous oxide users. Back, S, Kroon, E, Colyer-Patel, K, Cousijn, J. ...

Missbrauch von K.-o.-Tropfen mit Prävention entgegenwirken

06. Dezember 2023 | Verschiedene

Missbrauch von K.-o.-Tropfen mit Prävention entgegenwirken Berlin – Um den Missbrauch von K.-o.-Tropfen einzudämmen, sollten präventive Maßnahmen in Deutschland ausgebaut und die Akutversorgung verbessert werden. Zu dieser Erkenntnis kamen gester...

Psychedelika in der Therapie – Die Forschung holt auf (Video)

06. Dezember 2023 | Verschiedene

Psychedelika in der Therapie – Die Forschung holt auf (Video) Sie wurden verteufelt, verbannt und verboten: Psychedelische Substanzen wurden lange Zeit als Drogen abgetan. Doch in der Schweiz war es dank einer Ausnahmebewilligung des Bundesamts f...

Ampel-Koalition will Anbau und Vertrieb von Medizinalcannabis liberalisieren

06. Dezember 2023 | Cannabis als Medizin

Ampel-Koalition will Anbau und Vertrieb von Medizinalcannabis liberalisieren Berlin – Herstellung und Vertrieb von Medizinalcannabis in Deutschland sollen erleichtert werden. Darauf haben sich die Parteien der Regierungskoalition geeinigt. Auch d...

Usage and health perception of cannabidiol-containing products among the population in Germany: a descriptive study conducted in 2020 and 2021.

06. Dezember 2023 | Cannabis als Medizin

Usage and health perception of cannabidiol-containing products among the population in Germany: a descriptive study conducted in 2020 and 2021. Geppert J, Lietzow J, Hessel-Pras S, Kirsch F, Schäfer B, Sachse B. BMC Public Health. 20...

The holistic effects of medical cannabis compared to opioids on pain experience in Finnish patients with chronic pain.

06. Dezember 2023 | Cannabis als Medizin

The holistic effects of medical cannabis compared to opioids on pain experience in Finnish patients with chronic pain. Jylkkä J, Hupli A, Nikolaeva A, Alanen S, Back AE, Lindqvist S, Krabbe A, Lavie-Ajayi M, Kantonen O. J Cannabis Re...

Drug supply measures and drug overdose mortality in the era of fentanyl and stimulants.

04. Dezember 2023 | Fentanyl

Drug supply measures and drug overdose mortality in the era of fentanyl and stimulants. Cano M, Timmons P, Hooten M, Sweeney K. Drug Alcohol Depend Rep. 2023 Oct 26;9:100197. doi: 10.1016/j.dadr.2023.100197. PMID: 37965239; PMCID: PM...

Captagon trafficking and the role of Europe

07. November 2023 | Amphetamine

Captagon trafficking and the role of Europe Introduction This report examines the role of Europe in the production and trafficking of captagon tablets. It includes an historical background, current production and trafficking, seizures, the c...

Prescription psychostimulants for the treatment of amphetamine-type stimulant use disorder: A systematic review and meta-analysis of randomized placebo-controlled trials.

06. November 2023 | Amphetamine

Prescription psychostimulants for the treatment of amphetamine-type stimulant use disorder: A systematic review and meta-analysis of randomized placebo-controlled trials. Sharafi, H, Bakouni, H, McAnulty, C, Drouin, S, Co...

Very high dose of pregabalin abuse: A case report.

06. November 2023 | Gabapentinoide

Very high dose of pregabalin abuse: A case report. Gupta M, Singh J, Udey B. Indian J Psychiatry. 2023 Sep;65(9):979-980. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_283_23. Epub 2023 Sep 5. PMID: 37841555; PMCID: PMC10569330. htt...

Combined use of cocaine and alcohol: A violent cocktail? A systematic review.

06. November 2023 | Alkohol

Combined use of cocaine and alcohol: A violent cocktail? A systematic review. van Amsterdam J, van den Brink W. J Forensic Leg Med. 2023 Oct 10;100:102597. doi: 10.1016/j.jflm.2023.102597. Epub ahead of print. PMID: 37832170. https://w...

Combined use of cocaine and alcohol: A violent cocktail? A systematic review.

06. November 2023 | Kokain

MAPP2 Study Collaborator Group. MDMA-assisted therapy for moderate to severe PTSD: a randomized, placebo-controlled phase 3 trial.

06. November 2023 | Amphetamine

MAPP2 Study Collaborator Group. MDMA-assisted therapy for moderate to severe PTSD: a randomized, placebo-controlled phase 3 trial. Mitchell JM, Ot'alora G M, van der Kolk B, Shannon S, Bogenschutz M, Gelfand Y, Paleos C, Nicholas CR, Quevedo...

Psychosocial and pharmacologic interventions for problematic methamphetamine use: Findings from a scoping review of the literature.

06. November 2023 | Amphetamine

Psychosocial and pharmacologic interventions for problematic methamphetamine use: Findings from a scoping review of the literature. Hersi M, Corace K, Hamel C, Esmaeilisaraji L, Rice D, Dryburgh N, et al. (2023) PLoS ONE 18(10): e02927...

Gabapentin as Adjunctive Therapy in Neonatal Opioid Withdrawal Syndrome: A Case Series.

05. November 2023 | Gabapentinoide

Gabapentin as Adjunctive Therapy in Neonatal Opioid Withdrawal Syndrome: A Case Series. Patz C, Liviskie C, Bird M, Zeller B, Vesoulis ZA, Smyser CD, McPherson C. J Pediatr Pharmacol Ther. 2023;28(4):368-373. doi: 10.5863/1551-6776-28....

Scaling Up Point-of-Care Fentanyl Testing — A Step Forward

29. Oktober 2023 | Fentanyl

Scaling Up Point-of-Care Fentanyl Testing — A Step Forward Brian S. Barnett, M.D., Peter R. Chai, M.D., M.M.S., and Joji Suzuki, M.D. NEJM, October 28, 2023, DOI: 10.1056/NEJMp2308525 Abstract https://www.nejm.org/doi/full/10.1056/NEJMp2308525

Commentary on Foot et al.: Clinical considerations in addressing comorbid stimulant use in opioid use disorder.

28. Oktober 2023 | Amphetamine

Commentary on Foot et al.: Clinical considerations in addressing comorbid stimulant use in opioid use disorder. Shulman, M., Greiner, M. and Bisaga, A. (2023), Addiction. doi.org/10.1111/add.16374 https://onlinelibrary.wiley.com/doi/ful...

Israel. This is the drug Hamas terrorists took to help them slaughter Israelis

21. Oktober 2023 | Amphetamine

Israel. This is the drug Hamas terrorists took to help them slaughter Israelis Captagon pills were found in the pockets of Hamas terrorists. (Jerusalem Post, Israel, 19.10.2023) https://www.jpost.com/health-and-wellness/article-769250

Pro und Contra: Leistungssteigerung und gesellschaftlicher Nutzen durch Neuroenhancement

20. Oktober 2023 | Verschiedene

Pro und Contra: Leistungssteigerung und gesellschaftlicher Nutzen durch Neuroenhancement Berlin – Seit rund 20 Jahren diskutiert nicht nur die Fachwelt über Neuroenhancement – auch die Medien griffen das Thema immer wieder auf. Bei Neuroenhancern ...

USA. UC Berkeley Center for the Science of Psychedelics - Exploring the potential of psychedelics for the betterment of all.

20. Oktober 2023 | Verschiedene

USA. UC Berkeley Center for the Science of Psychedelics - Exploring the potential of psychedelics for the betterment of all. Learn about the latest research, announcements, and initiatives at BCSP. (aufgerufen am 19.10.2023) https:...

Reporting from the rave underground: 5 Questions for drugs journalist Michelle Lhooq

20. Oktober 2023 | Verschiedene

Reporting from the rave underground: 5 Questions for drugs journalist Michelle Lhooq Lhooq discusses psychedelic trends in the rave scene. (The Microdose, USA, 16.10.2023) https://themicrodose.substack.com/p/reporting-from-the-rave-underground

Confirmed: Intermittent Use of Benzodiazepines Is the Safest Option

16. Oktober 2023 | Benzodiazepine

Confirmed: Intermittent Use of Benzodiazepines Is the Safest Option BARCELONA — Intermittent benzodiazepine use significantly reduces the risk for falls, fractures, and mortality in older adults compared with chronic use of these medications, resu...

Aus illegalen Drogenlaboren: Neue Opioide überschwemmen den Markt – mehr zur Wirkung und zu den Gefahren der Nitazene

10. Oktober 2023 | Opioide

Aus illegalen Drogenlaboren: Neue Opioide überschwemmen den Markt – mehr zur Wirkung und zu den Gefahren der Nitazene Das synthetische Opioid Fentanyl ist bekannt dafür, aufgrund von Missbrauch viele Menschenleben gekostet zu haben – vor all...

Verordnung von Cannabis in Arzneimittel-Richtlinie geregelt

08. Oktober 2023 | Cannabis als Medizin

Crack auf dem Vormarsch? Konsequenzen für Drogenhilfe und Kommunen

08. Oktober 2023 | Kokain

Crack auf dem Vormarsch? Konsequenzen für Drogenhilfe und Kommunen rausch - Wiener Zeitschrift für Suchttherapie, 12. Jahrgang - Heft 3-2023, Schwerpunktheft Pabst, 2022 ISSN 2190-443X Preis: 15,- € https://www.psychologie-aktuell.com/journale/rau...

Cannabis Use Frequency and Cannabis-Related Consequences in High-Risk Young Adults Across Cannabis Legalization.

08. Oktober 2023 | Cannabis als Rauschmittel

Cannabis Use Frequency and Cannabis-Related Consequences in High-Risk Young Adults Across Cannabis Legalization. Doggett A, Belisario K, McDonald AJ, Ferro MA, Murphy JG, MacKillop J. JAMA Netw Open. 2023 Sep 5;6(9):e2336035. doi: 10.1...

Cannabis sativa: origin and history, glandular trichome development, and cannabinoid biosynthesis.

08. Oktober 2023 | Cannabis als Rauschmittel

Cannabis sativa: origin and history, glandular trichome development, and cannabinoid biosynthesis. Xie Z, Mi Y, Kong L, Gao M, Chen S, Chen W, Meng X, Sun W, Chen S, Xu Z. Hortic Res. 2023 Jul 26;10(9):uhad150. doi: 10.1093/hr/uhad150....

Cannabis sativa: origin and history, glandular trichome development, and cannabinoid biosynthesis.

08. Oktober 2023 | Cannabis als Medizin

Health-related quality of life in patients accessing medicinal cannabis in Australia: The QUEST initiative results of a 3-month follow-up observational study.

08. Oktober 2023 | Cannabis als Medizin

Health-related quality of life in patients accessing medicinal cannabis in Australia: The QUEST initiative results of a 3-month follow-up observational study. Tait M-A, Costa DS, Campbell R, Norman R, Warne LN, Schug S, et al. (2023) P...

Chronic 3,4-Methylenedioxymethamphetamine (MDMA) Use Is Related to Glutamate and GABA Concentrations in the Striatum But Not the Anterior Cingulate Cortex.

08. Oktober 2023 | Amphetamine

Chronic 3,4-Methylenedioxymethamphetamine (MDMA) Use Is Related to Glutamate and GABA Concentrations in the Striatum But Not the Anterior Cingulate Cortex. Zimmermann J, Zölch N, Coray R, Bavato F, Friedli N, Baumgartner MR, Steuer AE, Opitz...

Mirtazapine: A One-Stop Strategy for Treatment of Opioid Withdrawal Symptoms.

08. Oktober 2023 | Verschiedene

Mirtazapine: A One-Stop Strategy for Treatment of Opioid Withdrawal Symptoms. Lalani E, Menon R, Mufti MA, Kumfa C, Raji M. Cureus. 2023 Aug 20;15(8):e43821. doi: 10.7759/cureus.43821. PMID: 37736438; PMCID: PMC10509332. https://www.nc...

MOMEDA – Zielsetzung und Indikatoren eines Monitoring zum Gebrauch von Medikamenten mit Missbrauchs- und Abhängigkeitspotenzial in Deutschland

06. Oktober 2023 | Verschiedene

MOMEDA – Zielsetzung und Indikatoren eines Monitoring zum Gebrauch von Medikamenten mit Missbrauchs- und Abhängigkeitspotenzial in Deutschland Mit dem Projekt sollten die Möglichkeiten eines in Deutschland einzusetzenden Monitorings von Medi...

Endogenous opiates and behavior: 2022.

04. Oktober 2023 | Opioide

Endogenous opiates and behavior: 2022. Bodnar RJ. Peptides. 2023 Nov;169:171095. doi: 10.1016/j.peptides.2023.171095. Epub 2023 Sep 12. PMID: 37704079. Abstract https://pubmed.ncbi.nlm.nih.gov/37704079/

Association between cannabis use and symptom dimensions in schizophrenia spectrum disorders: an individual participant data meta-analysis on 3053 individuals

04. Oktober 2023 | Cannabis als Rauschmittel

Association between cannabis use and symptom dimensions in schizophrenia spectrum disorders: an individual participant data meta-analysis on 3053 individuals Argote, Mathilde et al. eClinicalMedicine, Volume 64, 102199 https://www.thelancet.com/jo...

UK. Experts fear Fentanyl slipping into drugs 'under the radar' - as at least 70 types found in UK

04. Oktober 2023 | Fentanyl

UK. Experts fear Fentanyl slipping into drugs 'under the radar' - as at least 70 types found in UK At least 70 versions of the synthetic opioid, Fentanyl, have now been detected in the UK, a former Government drug advisor has told LBC. (LBC – Lead...

MDMA-unterstützte Psychotherapie bei PTBS wirksam

04. Oktober 2023 | Amphetamine

MDMA-unterstützte Psychotherapie bei PTBS wirksam San Francisco – Die Wirksamkeit von MDMA-unterstützter Psychotherapie bei Posttraumatischer Belastungsstörung (PTBS) wurde jetzt in einer erweiterten Population bestätigt. In der nunmehr 2. Phase...

Mindzone. NEWS Quartalsupdate Q3|23

04. Oktober 2023 | Verschiedene

Mindzone. NEWS Quartalsupdate Q3|23 Wir freuen uns, Ihnen das dritte Quartals-Update 2023 zum Projekt „NEWS“ (für National Early Warning System), dem bundesweiten Frühwarnsystem zu Neuentwicklungen im Bereich psychoaktiver Substanzen und Medikamen...

TikTok-Trend Lachgas So gefährlich ist die Partydroge aus dem Luftballon (Video)

04. Oktober 2023 | Verschiedene

TikTok-Trend Lachgas So gefährlich ist die Partydroge aus dem Luftballon (Video) Die Droge ist legal, günstig und leicht zu bekommen: Lachgas wird bei Jugendlichen immer beliebter. Auf TikTok trenden Videos von berauschten Menschen. Was ist das fü...

Lachgas – kurzer Rausch mit langfristigen Folgen

04. Oktober 2023 | Verschiedene

Lachgas – kurzer Rausch mit langfristigen Folgen Für wenige Minuten steigt die Stimmung. Das Treibmittel Distickstoffmonoxid, besser bekannt als Lachgas, wird auch zu Rauschzwecken inhaliert. Doch langfristig kann der Konsum schwere Nervenschäden ...

Case Report: Buprenorphine-precipitated fentanyl withdrawal treated with high-dose buprenorphine.

04. Oktober 2023 | Fentanyl

Case Report: Buprenorphine-precipitated fentanyl withdrawal treated with high-dose buprenorphine. Bormann NL, Gout A, Kijewski V, Lynch A. F1000Res. 2023 Aug 10;11:487. doi: 10.12688/f1000research.120821.2. PMID: 37767082; PMCID: PMC10...

Novel multi-objective affinity approach allows to identify pH-specific μ-opioid receptor agonists.

04. Oktober 2023 | Opioide

Novel multi-objective affinity approach allows to identify pH-specific μ-opioid receptor agonists. Secker C, Fackeldey K, Weber M, Ray S, Gorgulla C, Schütte C. J Cheminform. 2023 Sep 19;15(1):85. doi: 10.1186/s13321-023-00746-4. ...

Fentanyl-Associated Overdose Deaths Outside the Hospital.

24. September 2023 | Fentanyl

Fentanyl-Associated Overdose Deaths Outside the Hospital. Jeffery MM, Stevens M, D'Onofrio G, Melnick ER. N Engl J Med. 2023 Jul 6;389(1):87-88. doi: 10.1056/NEJMc2304991. Epub 2023 Jun 21. PMID: 37342960; PMCID: PMC10388669. https://w...

Pharmacological and electronic cigarette interventions for smoking cessation in adults: component network meta‐analyses.

24. September 2023 | Nikotin

Pharmacological and electronic cigarette interventions for smoking cessation in adults: component network meta‐analyses. Lindson N, Theodoulou A, Ordóñez-Mena JM, Fanshawe TR, Sutton AJ, Livingstone-Banks J, Hajizadeh A, Zhu S, Aveyard P, Fr...

Psychedelic drug MDMA moves closer to US approval following success in PTSD trial

24. September 2023 | Amphetamine

Psychedelic drug MDMA moves closer to US approval following success in PTSD trial Long-awaited trial data show drug is effective at treating post-traumatic stress disorder in a diversity of people. (Nature, 14.09.2023) https://www.nature.com/artic...

MDMA-assisted therapy for moderate to severe PTSD: a randomized, placebo-controlled phase 3 trial.

24. September 2023 | Amphetamine

MDMA-assisted therapy for moderate to severe PTSD: a randomized, placebo-controlled phase 3 trial. Mitchell, J.M., Ot’alora G., M., van der Kolk, B. et al. Nat Med (2023). doi.org/10.1038/s41591-023-02565-4 https://www.nature.com/a...

Effects of U.S. State Medical Cannabis Laws on Treatment of Chronic Noncancer Pain.

24. September 2023 | Cannabis als Medizin

Effects of U.S. State Medical Cannabis Laws on Treatment of Chronic Noncancer Pain. Emma E. McGinty, Kayla N. Tormohlen, Nicholas J. Seewald, et al. Ann Intern Med. [Epub 4 July 2023]. doi:10.7326/M23-0053 Abstract https://www.acpjourn...

La problématique du crack à Genève

24. September 2023 | Kokain

La problématique du crack à Genève Situation et réponses - Rapport de recherche N° 153. (Addiction Suisse, 2023) https://www.suchtschweiz.ch/publication/la-problematique-du-crack-a-geneve/

Is Brazil’s ‘Anti-Cocaine’ Vaccine a Solution or Social Control?

24. September 2023 | Kokain

Is Brazil’s ‘Anti-Cocaine’ Vaccine a Solution or Social Control? The recent announcement of additional funding for an “anti-cocaine” vaccine has raised concern across Brazilian harm reduction organisations. Experts from the region question the vac...

Was genau ist Crack? Ist es gefährlicher als Kokain, und was macht es mit dem Gehirn? Die wichtigsten Fakten zu dieser Droge

24. September 2023 | Kokain

Was genau ist Crack? Ist es gefährlicher als Kokain, und was macht es mit dem Gehirn? Die wichtigsten Fakten zu dieser Droge In Berlin, Zürich, Paris, Genf und vielen anderen Städten nimmt der Crack-Konsum zu, teilweise bilden sich Strassenszenen....

Positionspapier der Deutschen Hauptstelle für Suchtfragen e.V. (DHS): Reduzierung der Risiken des Cannabiskonsums

14. September 2023 | Cannabis als Rauschmittel

Positionspapier der Deutschen Hauptstelle für Suchtfragen e.V. (DHS): Reduzierung der Risiken des Cannabiskonsums Von einer Arbeitsgruppe (unter Mitarbeit von G. Bischof, S. Eckhard, B. Fischer, D. Hermann, E. Hoch, D. Kratz, L. Krüger-Rosenke, K....

Long-term use of benzodiazepines in chronic insomnia: a European perspective.

14. September 2023 | Benzodiazepine

Long-term use of benzodiazepines in chronic insomnia: a European perspective. Soyka M, Wild I, Caulet B, Leontiou C, Lugoboni F, Hajak G. Front Psychiatry. 2023 Aug 2;14:1212028. doi: 10.3389/fpsyt.2023.1212028. PMID: 37599882; PMCID: ...

The impact of methamphetamine use on medications for opioid use disorder (MOUD) treatment retention: a scoping review.

14. September 2023 | Amphetamine

The impact of methamphetamine use on medications for opioid use disorder (MOUD) treatment retention: a scoping review. Russell C, Law J, Imtiaz S, Rehm J, Le Foll B, Ali F. Addict Sci Clin Pract. 2023 Aug 16;18(1):48. doi: 10.1186/s137...

Prescription amphetamines in people with opioid use disorder and co-occurring psychostimulant use disorder initiating buprenorphine: an analysis of treatment retention and overdose risk

14. September 2023 | Amphetamine

Prescription amphetamines in people with opioid use disorder and co-occurring psychostimulant use disorder initiating buprenorphine: an analysis of treatment retention and overdose risk Tardelli V, Xu KY, Bisaga A, et al BMJ Ment Health 2023;26:e3...

Australien. Australien erlaubt Partydrogen wie MDMA als Medizin

14. September 2023 | Amphetamine

Australien. Australien erlaubt Partydrogen wie MDMA als Medizin Sydney – In Australien dürfen seit Monatsbeginn die Rauschmittel Ecstasy und Magic Mushrooms als Arzneimittel für therapeutische Zwecke eingesetzt werden. Down Under ist damit das ers...

Involvement of the Opioid Peptide Family in Cancer Progression.

14. September 2023 | Opioide

Involvement of the Opioid Peptide Family in Cancer Progression. Sánchez ML, Rodríguez FD, Coveñas R. Biomedicines. 2023; 11(7):1993. doi.org/10.3390/biomedicines11071993 https://www.mdpi.com/2227-9059/11/7/1993

Five-Year Trajectories of Prescription Opioid Use.

14. September 2023 | Opioide

Five-Year Trajectories of Prescription Opioid Use. Gisev N, Buizen L, Hopkins RE, et al. JAMA Netw Open. 2023;6(8):e2328159. doi:10.1001/jamanetworkopen.2023.28159 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2808144

Opioids and opioid receptors; understanding pharmacological mechanisms as a key to therapeutic advances and mitigation of the misuse crisis.

14. September 2023 | Opioide

Opioids and opioid receptors; understanding pharmacological mechanisms as a key to therapeutic advances and mitigation of the misuse crisis. Lambert DG. BJA Open. 2023 May 17;6:100141. doi: 10.1016/j.bjao.2023.100141. PMID: 37588171; P...

25 Years On, OxyContin Marketing Push Still Exacting a Deadly Toll

14. September 2023 | Opioide

25 Years On, OxyContin Marketing Push Still Exacting a Deadly Toll Aggressive marketing of OxyContin in the mid-1990s not only fueled the opioid crisis but also the spread of infectious diseases associated with injection drug use, a new analysis s...

Xylazine - Medical and Public Health Imperatives.

14. September 2023 | Verschiedene

Xylazine - Medical and Public Health Imperatives. Gupta R, Holtgrave DR, Ashburn MA. N Engl J Med. 2023 Jun 15;388(24):2209-2212. doi: 10.1056/NEJMp2303120. Epub 2023 Apr 26. PMID: 37099338. https://www.nejm.org/doi/10.1056/NEJMp2303120

Xylazin: Das Wichtigste zur "Zombie-Droge"

14. September 2023 | Verschiedene

Xylazin: Das Wichtigste zur "Zombie-Droge" Insbesondere in den USA strecken Drogendealer Fentanyl, Heroin oder Kokain immer häufiger mit dem Tierberuhigungsmittel Xylazin – auch als „Zombie-Droge“ oder „Tranq“ bekannt. Anders als bei großen Pferde...

Psychedelics as Therapeutics—Potential and Challenges.

14. September 2023 | Verschiedene

Psychedelics as Therapeutics—Potential and Challenges. Volkow ND, Gordon JA, Wargo EM. JAMA Psychiatry. Published online July 26, 2023. doi:10.1001/jamapsychiatry.2023.1968 https://jamanetwork.com/journals/jamapsychiatry/article-abstra...

Xylazin als Streckmittel: Vom Tierberuhigungsmittel zur „Zombie-Droge“ – mit lebensgefährlichen Nebenwirkungen

14. September 2023 | Verschiedene

Xylazin als Streckmittel: Vom Tierberuhigungsmittel zur „Zombie-Droge“ – mit lebensgefährlichen Nebenwirkungen Insbesondere in den USA strecken Drogendealer Fentanyl, Heroin oder Kokain immer häufiger mit dem Tierberuhigungsmittel Xylazin – a...

UNODC. UNODC Early Warning Advisory Toxicology Highlights

14. September 2023 | Verschiedene

UNODC. UNODC Early Warning Advisory Toxicology Highlights Volume VI, August 2023, UNODC Wien Current NPS Threats https://www.unodc.org/res/scientists/ewa/Current_NPS_Threats_VI.pdf

The New Zealand drug harms ranking study: A multi-criteria decision analysis.

14. September 2023 | Verschiedene

The New Zealand drug harms ranking study: A multi-criteria decision analysis. Crossin R, Cleland L, Wilkins C, et al. Journal of Psychopharmacology. 2023;37(9):891-903. doi:10.1177/02698811231182012 https://journals.sagepub.com/doi/10....

The emerging fentanyl–xylazine syndemic in the USA: challenges and future directions

14. September 2023 | Verschiedene

The emerging fentanyl–xylazine syndemic in the USA: challenges and future directions Zhu, David T et al. The Lancet, Volume 0, Issue 0 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01686-0/fulltext

Widespread Distribution of Xylazine Detected Throughout the United States in Healthcare Patient Samples.

14. September 2023 | Verschiedene

Widespread Distribution of Xylazine Detected Throughout the United States in Healthcare Patient Samples. Holt AC, Schwope DM, Le K, Schrecker JP, Heltsley R. J Addict Med. 2023 Jul-Aug 01;17(4):468-470. doi: 10.1097/ADM.000000000000113...

Pharmacology and toxicology of xylazine: quid novum?

14. September 2023 | Verschiedene

Pharmacology and toxicology of xylazine: quid novum? Malaca S, Pesaresi M, Kapoor A, Berretta P, Busardò FP, Pirani F. Eur Rev Med Pharmacol Sci. 2023 Aug;27(15):7337-7345. doi: 10.26355/eurrev_202308_33305. PMID: 37606142. https://www...

An Update on Psychoactive Substances: Pharmacology and Toxicology Issues.

14. September 2023 | Verschiedene

An Update on Psychoactive Substances: Pharmacology and Toxicology Issues. Chiappini S, Schifano F. Pharmaceuticals (Basel). 2023 Aug 18;16(8):1177. doi: 10.3390/ph16081177. PMID: 37631091; PMCID: PMC10458262. https://www.ncbi.nlm.nih.g...

The New Stealth Drug on the Street: A Narrative Review of Xylazine as a Street Drug.

14. September 2023 | Verschiedene

The New Stealth Drug on the Street: A Narrative Review of Xylazine as a Street Drug. Pergolizzi J Jr, LeQuang JAK, Magnusson P, Miller TL, Breve F, Varrassi G. Cureus. 2023 Jun 26;15(6):e40983. doi: 10.7759/cureus.40983. PMID: 37503500...

Old Drugs and New Challenges: A Narrative Review of Nitazenes.

14. September 2023 | Verschiedene

Old Drugs and New Challenges: A Narrative Review of Nitazenes. Pergolizzi J Jr, Raffa R, LeQuang JAK, Breve F, Varrassi G. Cureus. 2023 Jun 21;15(6):e40736. doi: 10.7759/cureus.40736. PMID: 37485167; PMCID: PMC10361140. https://www.ncbi.nlm....

From Antidepressant Tianeptine to Street Drug ZaZa: A Narrative Review.

14. September 2023 | Verschiedene

From Antidepressant Tianeptine to Street Drug ZaZa: A Narrative Review. Wagner ML, Pergolizzi J Jr, LeQuang JAK, Breve F, Varrassi G. Cureus. 2023 Jun 20;15(6):e40688. doi: 10.7759/cureus.40688. PMID: 37485121; PMCID: PMC10359047. https://ww...

Benzodiazepine use, quality of life and psychiatric symptom burden in oral and injectable opioid agonist treatment: a cross-sectional study.

14. September 2023 | Benzodiazepine

Benzodiazepine use, quality of life and psychiatric symptom burden in oral and injectable opioid agonist treatment: a cross-sectional study. Meyer M, Gygli F, Westenberg JN, Schmid O, Strasser J, Lang UE, Dürsteler KM, Vogel M. Addict ...

Abuse and addiction in gabapentinoid drug users for neuropathic pain.

14. September 2023 | Gabapentinoide

Abuse and addiction in gabapentinoid drug users for neuropathic pain. Kiliç Z, Aydin Özaslan E. Eur Rev Med Pharmacol Sci. 2023 Jun;27(12):5378-5389. doi: 10.26355/eurrev_202306_32772. PMID: 37401272. https://www.europeanreview.org/art...

Cannabis use to manage opioid cravings among people who use unregulated opioids during a drug toxicity crisis.

14. September 2023 | Cannabis als Medizin

Cannabis use to manage opioid cravings among people who use unregulated opioids during a drug toxicity crisis. Reddon H, Lake S, Socias ME, Hayashi K, DeBeck K, Walsh Z, Milloy MJ. Int J Drug Policy. 2023 Jul 21;119:104113. doi: 10.101...

Delta-9-tetrahydrocannabinol modulates pain sensitivity among persons receiving opioid agonist therapy for opioid use disorder: A within-subject, randomized, placebo-controlled laboratory study.

14. September 2023 | Cannabis als Medizin

Delta-9-tetrahydrocannabinol modulates pain sensitivity among persons receiving opioid agonist therapy for opioid use disorder: A within-subject, randomized, placebo-controlled laboratory study. De Aquino JP, Meyerovich J, Xie CZ, Ranga...

Cannabidiol acts as molecular switch in innate immune cells to promote the biosynthesis of inflammation-resolving lipid mediators

14. September 2023 | Cannabis als Medizin

Cannabidiol acts as molecular switch in innate immune cells to promote the biosynthesis of inflammation-resolving lipid mediators Peltner, Lukas K. et al. Cell Chemical Biology, Volume 0, Issue 0 https://www.cell.com/cell-chemical-biology/fu...

Wie Cannabinoide gegen Entzündungen wirken

14. September 2023 | Cannabis als Medizin

Wie Cannabinoide gegen Entzündungen wirken Jena – Inhaltsstoffe aus der Cannabispflanze können Entzündungen entgegenwirken. Eine internationale Arbeitsgruppe hat jetzt unter Leitung des Instituts für Pharmazie der Universität Jena einen zugrundeli...

Illicitly Manufactured Fentanyl–Involved Overdose Deaths with Detected Xylazine — United States, January 2019–June 2022.

14. September 2023 | Fentanyl

Illicitly Manufactured Fentanyl–Involved Overdose Deaths with Detected Xylazine — United States, January 2019–June 2022. Kariisa M, O’Donnell J, Kumar S, Mattson CL, Goldberger BA. MMWR Morb Mortal Wkly Rep 2023;72:721–727. doi.org/1...

Understanding intentionality of fentanyl use and drug overdose risk: Findings from a mixed methods study of people who inject drugs in New York City,

14. September 2023 | Fentanyl

Understanding intentionality of fentanyl use and drug overdose risk: Findings from a mixed methods study of people who inject drugs in New York City, Courtney McKnight, Chenziheng Allen Weng, Marley Reynoso, Sarah Kimball, Lily M. Thompson, Don De...

Fentanyl - Informationen für Suchtfachpersonen – Faktenblatt,

14. September 2023 | Fentanyl

Fentanyl - Informationen für Suchtfachpersonen – Faktenblatt, Herausgeber: InfodroG, Schweizerische Koordeinations- und Fachstelle Sucht, Bern, 2023 https://www.infodrog.ch/files/content/factsheets/2023-08_infodrog_faktenblatt_fentanyl_de.pdf

The emerging fentanyl–xylazine syndemic in the USA: challenges and future directions

14. September 2023 | Fentanyl

Focus on fentanyl in females: Sex and gender differences in the physiological and behavioral effects of fentanyl.

14. September 2023 | Fentanyl

Focus on fentanyl in females: Sex and gender differences in the physiological and behavioral effects of fentanyl. Little KM, Kosten TA. Front Neuroendocrinol. 2023 Aug 18;71:101096. doi: 10.1016/j.yfrne.2023.101096. Epub ahead of print...

Fentanyl Facts and Overdose Risk: An Addiction Policy Forum Course

14. September 2023 | Fentanyl

Fentanyl Facts and Overdose Risk: An Addiction Policy Forum Course Welcome to our course on Fentanyl Facts and Increased Overdose Risk. This course was developed by the Addiction Policy Forum and JCOIN to share facts about fentanyl in the U....

Fentanyl and other New Psychoactive Synthetic Opioids. Challenges to Prevention and Treatment.

14. September 2023 | Fentanyl

Fentanyl and other New Psychoactive Synthetic Opioids. Challenges to Prevention and Treatment. Albores-García D, Cruz SL. Rev Invest Clin. 2023;75(3):93-104. doi: 10.24875/RIC.23000109. PMID: 37441771. https://clinicalandtranslationali...

Development of a neural network model to predict the presence of fentanyl in community drug samples.

14. September 2023 | Fentanyl

Development of a neural network model to predict the presence of fentanyl in community drug samples. Ti L, Grant CJ, Tobias S, Hore DK, Laing R, Marshall BDL (2023) PLoS ONE 18(7): e0288656. doi.org/10.1371/journal.pone.0288656 https:/...

Fentanyl Concentration in Drug Checking Samples and Risk of Overdose Death in Vancouver, Canada

14. September 2023 | Fentanyl

Fentanyl Concentration in Drug Checking Samples and Risk of Overdose Death in Vancouver, Canada Kennedy, Mary Clare et al. American Journal of Preventive Medicine, Volume 0, Issue 0 Abstract https://www.ajpmonline.org/article/S0749-3797(23)0...

Fentanyl and other New Psychoactive Synthetic Opioids. Challenges to Prevention and Treatment.

14. September 2023 | Fentanyl

THE toll of opioid dependence: A research report on the possible role of Toll-like receptor-4 and related immune markers in opioid dependence.

14. September 2023 | Opioide

THE toll of opioid dependence: A research report on the possible role of Toll-like receptor-4 and related immune markers in opioid dependence. Mahintamani T, Basu D, Ghosh A, Luthra-Guptasarma M. Indian J Psychiatry. 2023 Jun;65(6):626...

Cannabis-based medicinal products for the treatment of Long COVID symptoms: current and potential applications

13. September 2023 | Cannabis als Medizin

Cannabis-based medicinal products for the treatment of Long COVID symptoms: current and potential applications Hannah Thurgur, Anne Katrin Schlag, Elizabeth Iveson, Adele Hosseini, Michael Lynskey, David J. Nutt Drug ...

Preliminary feasibility of integrating tobacco treatment into SUD peer recovery coaching: a mixed-methods study of peer recovery coaches.

30. Juni 2023 | Nikotin

Preliminary feasibility of integrating tobacco treatment into SUD peer recovery coaching: a mixed-methods study of peer recovery coaches. Streck, J.M., Regan, S., Werner, M. et al. Addict Sci Clin Pract 18, 25 (2023). doi.org/10....

Werden wir mehr Drogen nehmen?

30. Juni 2023 | Verschiedene

Werden wir mehr Drogen nehmen? Drogen begleiten die Menschheit schon immer. Und doch haben sie ein miserables Image. Wissenschaftler:innen sind sich dennoch schon lange sicher: Unter bestimmten Umständen können wir uns bestimmte Psychedelika zunu...

Left behind in pain - Extent and causes of global variations in access to morphine for medical use and actions to improve safe access.

28. Juni 2023 | Opioide

Left behind in pain - Extent and causes of global variations in access to morphine for medical use and actions to improve safe access. The world is facing two crises related to the use of opioids. In the first, inappropriate use and over-pr...

WHO. Zugang zu morphinhaltigen Schmerzmitteln weltweit sehr ungleich verteilt

28. Juni 2023 | Opioide

WHO. Zugang zu morphinhaltigen Schmerzmitteln weltweit sehr ungleich verteilt Genf – Die weltweite Verteilung des Schmerzmittels Morphin entspricht nicht dem medizinischen Bedarf. Das kritisiert die Weltgesundheitsorganisation (WHO) in einem neue...

Clinical outcome data of anxiety patients treated with cannabis-based medicinal products in the United Kingdom: a cohort study from the UK Medical Cannabis Registry.

28. Juni 2023 | Cannabis als Medizin

Clinical outcome data of anxiety patients treated with cannabis-based medicinal products in the United Kingdom: a cohort study from the UK Medical Cannabis Registry. Rifkin-Zybutz R, Erridge S, Holvey C, Coomber R, Gaffney J, Lawn W, Barros...

Psychedelics reopen the social reward learning critical period.

17. Juni 2023 | Verschiedene

Psychedelics reopen the social reward learning critical period. Nardou, R., Sawyer, E., Song, Y.J. et al. Nature (2023). doi.org/10.1038/s41586-023-06204-3 https://www.nature.com/articles/s41586-023-06204-3

Testing for Fentanyl — Urgent Need for Practice-Relevant and Public Health Research

11. Juni 2023 | Fentanyl

Testing for Fentanyl — Urgent Need for Practice-Relevant and Public Health Research Nora D. Volkow, Robert M. Califf, Marta Sokolowska, Lawrence A. Tabak, and Wilson M. Compton NEJM, June 10, 2023, DOI: 10.1056/NEJMp2302857 https://www.nejm.org...

A medication-based intervention for people who use benzodiazepines

09. Juni 2023 | Benzodiazepine

A medication-based intervention for people who use benzodiazepines Karen Berry talks about prescribing protocols for people who are dependent on benzodiazepines, and why benzodiazepines have been such a prominent feature in drug-related dea...

The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study

08. Juni 2023 | Cannabis als Rauschmittel

The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study Cheng, Weiqiu et al. The Lancet Psychiatry, Volume 10, Issue 6, 441 - 451 https://www.thelancet.com/journals/lanpsy/article/PIIS2215-...

Bayern. Fentanyl war gestern

06. Juni 2023 | Gabapentinoide

Bayern. Fentanyl war gestern In der Drogenszene dominiert ein neuer Stoff namens Lyrica. Falsch kombiniert kann er tödlich sein. (Bayerische Staatszeitung, 02.06.2023) https://www.bayerische-staatszeitung.de/staatszeitung/politik/detailansicht-p...

Case report: A comatose patient with pregabalin overdose successfully treated with continuous renal replacement therapy.

06. Juni 2023 | Gabapentinoide

Case report: A comatose patient with pregabalin overdose successfully treated with continuous renal replacement therapy. Nielsen VT, Wijayasinghe N, Høgberg LCG, Bøgevig S. Front Med (Lausanne). 2023 Apr 24;10:1125653. doi: 10.3389/f...

Fentanyl Absorption, Distribution, Metabolism, and Excretion: Narrative Review and Clinical Significance Related to Illicitly Manufactured Fentanyl.

06. Juni 2023 | Fentanyl

Fentanyl Absorption, Distribution, Metabolism, and Excretion: Narrative Review and Clinical Significance Related to Illicitly Manufactured Fentanyl. Bird HE, Huhn AS, Dunn KE. J Addict Med. 2023 May 17. doi: 10.1097/ADM.0000000000001...

"Just another thing for me to stress off of:" Responses to Unintentional Fentanyl Use in a Community-based Study of People who Use Opioids.

06. Juni 2023 | Fentanyl

"Just another thing for me to stress off of:" Responses to Unintentional Fentanyl Use in a Community-based Study of People who Use Opioids. Lorvick J, Hemberg J, George M, Piontak J, Comfort M. Res Sq [Preprint]. 2023 Apr 27:rs.3.rs-...

Morphometrics of waterlogged archaeological seeds give new insights into the domestication and spread of Papaver somniferum L. in Western Europe.

06. Juni 2023 | Opioide

Morphometrics of waterlogged archaeological seeds give new insights into the domestication and spread of Papaver somniferum L. in Western Europe. Jesus A, Bonhomme V, Evin A, Soteras R, Jacomet S, Bouby L, Antolín F. PLoS One. 2023 M...

Cognitive test performance in chronic cannabis flower users, concentrate users, and non-users.

06. Juni 2023 | Cannabis als Rauschmittel

Cognitive test performance in chronic cannabis flower users, concentrate users, and non-users. Cuttler C, Petrucci AS, LaFrance EM. Sci Rep. 2023 May 18;13(1):8068. doi: 10.1038/s41598-023-35217-1. PMID: 37202444; PMCID: PMC10195824....

Major-Depression: Ketamin mindestens so wirksam wie Elektrokonvulsionstherapie

06. Juni 2023 | Verschiedene

Major-Depression: Ketamin mindestens so wirksam wie Elektrokonvulsionstherapie San Francisco – Infusionen mit dem Narkosemittel Ketamin in einer subanästhetischen Dosis haben in der bisher größten Vergleichsstudie bei Patienten mit behandlungsres...

BUPROPION MISUSE BY NASAL INSUFFLATION WITH A FATAL OUTCOME: CASE REPORT AND REVIEW.

06. Juni 2023 | Verschiedene

BUPROPION MISUSE BY NASAL INSUFFLATION WITH A FATAL OUTCOME: CASE REPORT AND REVIEW. Pereira S, Simas J, Mota P, Carvalho P, Pais J. Actas Esp Psiquiatr. 2023 Mar;51(2):84-87. Epub 2023 Mar 1. PMID: 37218103. https://www.actaspsiqui...

Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom.

06. Juni 2023 | Verschiedene

Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom. Tanna RS, Nguyen JT, Hadi DL, Layton ME, White JR, Cech NB, Oberlies NH, Rettie AE, Thummel KE, Paine MF. Clin Pharmacol Ther. 2023 Jun...

Systematic assessment of non-medical use of prescription drugs using doctor-shopping indicators: A nationwide, repeated cross-sectional study.

06. Juni 2023 | Verschiedene

Systematic assessment of non-medical use of prescription drugs using doctor-shopping indicators: A nationwide, repeated cross-sectional study. Soeiro T, Pradel V, Lapeyre-Mestre M, Micallef J. Addiction. 2023 May 19. doi: 10.1111/add...

Esketamine in treatment-resistant depression patients comorbid with substance-use disorder: A viewpoint on its safety and effectiveness in a subsample of patients from the REAL-ESK study.

06. Juni 2023 | Verschiedene

Esketamine in treatment-resistant depression patients comorbid with substance-use disorder: A viewpoint on its safety and effectiveness in a subsample of patients from the REAL-ESK study. Chiappini S, d'Andrea G, De Filippis S, Di Nicola M,...

WHO. ECDD Repository - Expert Committee on Drug Dependence Information Repository

06. Juni 2023 | Verschiedene

WHO. ECDD Repository - Expert Committee on Drug Dependence Information Repository The ECDD Information Repository is an open access database containing publications and information on psychoactive substances reviewed by the WHO Expert Committee o...

GHB - kleine Tropfen mit großer Wirkung

06. Juni 2023 | Verschiedene

GHB - kleine Tropfen mit großer Wirkung GHB ist nicht nur ein körpereigener Botenstoff im Gehirn. Als „Liquid Ecstasy“ oder „G“ wird GHB auch als Droge konsumiert, mitunter mit fataler Wirkung. Zwischen Rausch und Koma liegt nur ein schmaler Grat...

Verschreibungen von Cannabisarzneimitteln 2019–2022 - Ein Vergleich der Daten des Bundesinstituts für Arzneimittel und Medizinprodukte und der Barmer Ersatzkasse

06. Juni 2023 | Cannabis als Medizin

Verschreibungen von Cannabisarzneimitteln 2019–2022 - Ein Vergleich der Daten des Bundesinstituts für Arzneimittel und Medizinprodukte und der Barmer Ersatzkasse Prescriptions of cannabinoid drugs, 2019–2022—a comparison of data from the German F...

Goods and bads of endocannabinoid system as a therapeutic target:Lessons learned after 30 years.

06. Juni 2023 | Cannabis als Medizin

Goods and bads of endocannabinoid system as a therapeutic target:Lessons learned after 30 years. Maccarrone M, Di Marzo V, Gertsch J, Grether U, Howlett AC, Hua T, Makriyannis A, Piomelli D, Ueda N, van der Stelt M. Pharmacol Rev. 2023 May...

Medizinisches Cannabis bewährt sich bei Tumorschmerzen

06. Juni 2023 | Cannabis als Medizin

Medizinisches Cannabis bewährt sich bei Tumorschmerzen Montreal – Medizinisches Cannabis kann Krebsschmerzen lindern und die Gesamtzahl der eingenommenen Medikamente und Opioide verringern. Dies legen die Ergebnisse einer multizentrischen Registe...

Jeden Mittwoch um 18:15 Uhr: Fallbesprechung aus der Praxis der Cannabistherapie

06. Juni 2023 | Cannabis als Medizin

Jeden Mittwoch um 18:15 Uhr: Fallbesprechung aus der Praxis der Cannabistherapie CME-zertifizierte Fortbildungsreihe der ACM für Ärztinnen und Ärzte. Die Ärztekammer Westfalen-Lippe gewährt Teilnehmern für die 45-minütige Veranstaltung jeweils 2 ...

Fachverbände fordern dringende Reformen beim Cannabis-als-Medizin Gesetz - Versorgungssicherheit, Entbürokratisierung und Aufhebung der Einstufung als Betäubungsmittel im Fokus

29. Mai 2023 | Cannabis als Medizin

Fachverbände fordern dringende Reformen beim Cannabis-als-Medizin Gesetz - Versorgungssicherheit, Entbürokratisierung und Aufhebung der Einstufung als Betäubungsmittel im Fokus Mit Inkrafttreten des „Cannabis als Medizin”-Gesetzes 2017 wurd...

Enumerating contributions of fentanyls and other factors to the unprecedented 2020 rise in opioid overdose deaths: model-based analysis.

24. Mai 2023 | Fentanyl

Enumerating contributions of fentanyls and other factors to the unprecedented 2020 rise in opioid overdose deaths: model-based analysis. Stringfellow EJ, Lim TY, DiGennaro C, Hasgul Z, Jalali MS. PNAS Nexus. 2023 Mar 3;2(4):pgad064. ...

Nondisordered Cannabis Use Among US Adolescents.

24. Mai 2023 | Cannabis als Rauschmittel

Nondisordered Cannabis Use Among US Adolescents. Sultan RS, Zhang AW, Olfson M, Kwizera MH, Levin FR. JAMA Netw Open. 2023;6(5):e2311294. doi:10.1001/jamanetworkopen.2023.11294 https://jamanetwork.com/journa...

Cannabis, cannabinoids and psychosis: a balanced view.

24. Mai 2023 | Cannabis als Rauschmittel

Cannabis, cannabinoids and psychosis: a balanced view. D'Souza, D.C. (2023) World Psychiatry, 22: 231-232. doi.org/10.1002/wps.21075 https://onlinelibrary.wiley.com/doi/10.1002/wps.21075

Cochrane-Review. Nicotine receptor partial agonists for smoking cessation.

24. Mai 2023 | Nikotin

Cochrane-Review. Nicotine receptor partial agonists for smoking cessation. Livingstone-Banks J, Fanshawe TR, Thomas KH, Theodoulou A, Hajizadeh A, Hartman L, Lindson N. Cochrane Database of Systematic Reviews 2023, Issue 5. Art. No.:...

The effect of alcohol use on smoking cessation: A systematic review.

24. Mai 2023 | Nikotin

The effect of alcohol use on smoking cessation: A systematic review. van Amsterdam J, van den Brink W. Alcohol. 2023 Jun;109:13-22. doi: 10.1016/j.alcohol.2022.12.003. Epub 2023 Jan 21. PMID: 36690220. https://www.sciencedirect...

Cochrane-Review. Cytisin und Vareniclin zur Rauchentwöhnung

24. Mai 2023 | Nikotin

Cochrane-Review. Cytisin und Vareniclin zur Rauchentwöhnung Die Wirkstoffe Cytisin und Vareniclin können helfen, mit dem Rauchen aufzuhören. Teilweise schneiden sie dabei besser ab als andere Rauchentwöhnungsmittel. Das ergibt die zusammenfassend...

Within-subject, double-blind, randomized, placebo-controlled evaluation of combining the cannabinoid dronabinol and the opioid hydromorphone in adults with chronic pain.

24. Mai 2023 | Cannabis als Medizin

Within-subject, double-blind, randomized, placebo-controlled evaluation of combining the cannabinoid dronabinol and the opioid hydromorphone in adults with chronic pain. Campbell, C.M., Mun, C.J., Hamilton, K.R. et al. Neuropsychophar...

Assessment of Medical Cannabis and Health-Related Quality of Life.

24. Mai 2023 | Cannabis als Medizin

Assessment of Medical Cannabis and Health-Related Quality of Life. Arkell TR, Downey LA, Hayley AC, Roth S. JAMA Netw Open. 2023 May 1;6(5):e2312522. doi: 10.1001/jamanetworkopen.2023.12522. PMID: 37159196; PMCID: PMC10170337. https...

UNODC. UNODC New Psychoactive Substances Portal and International Collaborative Exercise Portal

19. Mai 2023 | Neue Psychoaktive Substanzen

UNODC. UNODC New Psychoactive Substances Portal and International Collaborative Exercise Portal Welcome to the online portals of the UNODC Laboratory and Scientific Service. From this page you can access both portals. Please click on the icons be...

Clinical Provider Quick Tips - Addressing Substance Use in Primary Care Settings

13. Mai 2023 | Fentanyl

Clinical Provider Quick Tips - Addressing Substance Use in Primary Care Settings Fentanyl Quick Tips Fentanyl use trends, overdose risks and tools for reducing risk, and relevant medications for opioid use disorders (MOUD) to treat patients with...

Synthetische Opioide in Deutschland - Bundesmodellprojekt RAFT (Präsentation)

08. Mai 2023 | Fentanyl

Synthetische Opioide in Deutschland - Bundesmodellprojekt RAFT (Präsentation) Rapid Fentanyl Tests in Drogenkonsumräumen (12/22-11/23) Projektleitung: Maria Kuban Projektbegleitung: Dirk Schäffer (Deutsche AIDS-Hilfe, Gefördert durch Bundesmin...

Synthetische Opioide in Deutschland - Bundesmodellprojekt RAFT (Präsentation) (2)

08. Mai 2023 | Fentanyl

Teilnehmer für Forschungsstudie gesucht

08. Mai 2023 | Opioide

Teilnehmer für Forschungsstudie gesucht Ein Forscherteam des Universitätsklinikums Hamburg Eppendorf (UKE) und der Universität Cambridge wollen herausfinden, wie sich regelmäßiger Konsum von Opiaten auf das Gehirn auswirkt und möglicherweise das ...

Global trends in antidepressant, atypical antipsychotic, and benzodiazepine use: A cross-sectional analysis of 64 countries.

08. Mai 2023 | Benzodiazepine

Global trends in antidepressant, atypical antipsychotic, and benzodiazepine use: A cross-sectional analysis of 64 countries. Alabaku O, Yang A, Tharmarajah S, Suda K, Vigod S, Tadrous M (2023) PLoS ONE 18(4): e0284389. doi.org/10.137...

Cocaine Seeking And Taking Are Oppositely Regulated By Dopamine.

08. Mai 2023 | Kokain

Cocaine Seeking And Taking Are Oppositely Regulated By Dopamine. Burgeno LM, Farero RD, Murray NL, Panayi MC, Steger JS, Soden ME, Evans SB, Sandberg SG, Willuhn I, Zweifel LS, Phillips PEM. bioRxiv [Preprint]. 2023 Apr 10:2023.04.09...

USA. DEA-Themenseite zu Fentanyl: “One Pill can kill”

08. Mai 2023 | Fentanyl

USA. DEA-Themenseite zu Fentanyl: “One Pill can kill” https://www.dea.gov/onepill

Monitoring for fentanyl within Australian supervised injecting facilities: Findings from feasibility testing of novel methods and collaborative workshops.

08. Mai 2023 | Fentanyl

Monitoring for fentanyl within Australian supervised injecting facilities: Findings from feasibility testing of novel methods and collaborative workshops. Nielsen S, Barratt M, Hiley S, Bartlett M, Latimer J, Jauncey M, Roux C, Morelato M, ...

Effects of Gabapentinoids on Heroin-Induced Ventilatory Depression and Reversal by Naloxone.

08. Mai 2023 | Gabapentinoide

Effects of Gabapentinoids on Heroin-Induced Ventilatory Depression and Reversal by Naloxone. Flynn SM, France CP. ACS Pharmacol Transl Sci. 2023 Mar 6;6(4):519-525. doi: 10.1021/acsptsci.2c00230. PMID: 37082751; PMCID: PMC10111619. ...

Rise of Pregabalin Poisoning and Abuse Cases in Serbia: A Ten-Year Retrospective Study.

08. Mai 2023 | Gabapentinoide

Rise of Pregabalin Poisoning and Abuse Cases in Serbia: A Ten-Year Retrospective Study. Antunovic M, Vucinic S, Kotur-Stevuljevic J, Krstic K, Jovic-Stosic J, Kilibarda V, Perkovic-Vukcevic N, Djordjevic S. Int J Gen Med. 2023 Apr 8;...

Prophylactic High-Dose Gabapentin Reduces Opiate Use during Radiation Therapy for Head and Neck Squamous Cell Carcinoma.

08. Mai 2023 | Gabapentinoide

Prophylactic High-Dose Gabapentin Reduces Opiate Use during Radiation Therapy for Head and Neck Squamous Cell Carcinoma. Qiu ML, Iovoli AJ, Khan M, Farrugia MK, Ma SJ, Singh AK. Cancers (Basel). 2023 Mar 28;15(7):2003. doi: 10.3390/c...

Trends in gabapentinoid prescribing in UK primary care using the Clinical Practice Research Datalink: an observational study.

08. Mai 2023 | Gabapentinoide

Trends in gabapentinoid prescribing in UK primary care using the Clinical Practice Research Datalink: an observational study. Ashworth J, Bajpai R, Muller S, Bailey J, Helliwell T, Harrisson SA, Whittle R, Mallen CD. Lancet Reg Healt...

Impact of cannabidiol on reward- and stress-related neurocognitive processes among individuals with opioid use disorder: A pilot, double-blind, placebo-controlled, randomized cross-over trial.

08. Mai 2023 | Cannabis als Medizin

Impact of cannabidiol on reward- and stress-related neurocognitive processes among individuals with opioid use disorder: A pilot, double-blind, placebo-controlled, randomized cross-over trial. Suzuki J, Prostko S, Szpak V, Chai PR, Spagnolo...

The evolving culture of medical cannabis in Canada for the management of chronic pain.

08. Mai 2023 | Cannabis als Medizin

The evolving culture of medical cannabis in Canada for the management of chronic pain. Clarke H, Fitzcharles M. Front Pharmacol. 2023 Apr 7;14:1153584. doi: 10.3389/fphar.2023.1153584. PMID: 37089954; PMCID: PMC10119390. https://www...

A Systematic Review of Abuse or Overprescription of Bupropion in American Prisons and a Synthesis of Case Reports on Bupropion Abuse in American Prison and Non-prison Systems.

08. Mai 2023 | Verschiedene

A Systematic Review of Abuse or Overprescription of Bupropion in American Prisons and a Synthesis of Case Reports on Bupropion Abuse in American Prison and Non-prison Systems. Aikoye S, Basiru TO, Nwoye I, Adereti I, Asuquo S, Ezeokoli A, H...

Xylazine in the Opioid Epidemic: A Systematic Review of Case Reports and Clinical Implications.

08. Mai 2023 | Verschiedene

Xylazine in the Opioid Epidemic: A Systematic Review of Case Reports and Clinical Implications. Ayub S, Parnia S, Poddar K, Bachu AK, Sullivan A, Khan AM, Ahmed S, Jain L. Cureus. 2023 Mar 29;15(3):e36864. doi: 10.7759/cureus.36864. ...

Overview of blood-brain barrier dysfunction in methamphetamine abuse.

08. Mai 2023 | Amphetamine

Overview of blood-brain barrier dysfunction in methamphetamine abuse. Pang L, Wang Y. Biomed Pharmacother. 2023 May;161:114478. doi: 10.1016/j.biopha.2023.114478. Epub 2023 Mar 14. PMID: 37002574. https://www.sciencedirect.com/scien...

Papaverine: A Miraculous Alkaloid from Opium and Its Multimedicinal Application.

05. Mai 2023 | Opioide

Papaverine: A Miraculous Alkaloid from Opium and Its Multimedicinal Application. Ashrafi S, Alam S, Sultana A, Raj A, Emon NU, Richi FT, Sharmin T, Moon M, Park MN, Kim B. Molecules. 2023 Mar 31;28(7):3149. doi: 10.3390/molecules2807...

A Visit With Raphael Mechoulam, the Israeli Godfather of Cannabinoid Research

05. Mai 2023 | Cannabis als Medizin

A Visit With Raphael Mechoulam, the Israeli Godfather of Cannabinoid Research The 90-year-old scientist who first isolated THC is still addicted to research, studying the beneficial effects of cannabis on trauma, colitis, autism, and more. (Table...

Stress-related neuropeptide systems as targets for treatment of alcohol addiction: A clinical perspective.

05. Mai 2023 | Alkohol

Stress-related neuropeptide systems as targets for treatment of alcohol addiction: A clinical perspective. Heilig, M. J Intern Med. 2023; 293: 559– 573. https://onlinelibrary.wiley.com/doi/full/10.1111/joim.13636

Correlates of Heroin Use, Pharmaceutical Fentanyl Misuse, and Dual Heroin-Fentanyl Use: Evidence from the U.S.

05. Mai 2023 | Fentanyl

Correlates of Heroin Use, Pharmaceutical Fentanyl Misuse, and Dual Heroin-Fentanyl Use: Evidence from the U.S. Kelly BC, Vuolo M. Drugs Habits Soc Policy. 2023 Mar;24(1):14-25. doi: 10.1108/dhs-04-2022-0019. Epub 2022 Sep 22. PMID: 3...

Opioids on Top of Opioids: Treating Acute Pain in Patients With OUD (Video)

30. April 2023 | Opioide

Opioids on Top of Opioids: Treating Acute Pain in Patients With OUD (Video) Matthew F. Watto, MD; Paul N. Williams, MD Medscape, USA, 23.04.2023, Video, 07.53) https://www.medscape.com/viewarticle/987072

Xylazine - Medical and Public Health Imperatives.

30. April 2023 | Verschiedene

Xylazine - Medical and Public Health Imperatives. Gupta R, Holtgrave DR, Ashburn MA. N Engl J Med. 2023 Apr 26. doi: 10.1056/NEJMp2303120. Epub ahead of print. PMID: 37099338. https://www.nejm.org/doi/full/10.1056/NEJMp2303120

Association of Pharmacological Treatments and Hospitalization and Death in Individuals With Amphetamine Use Disorders in a Swedish Nationwide Cohort of 13 965 Patients.

30. April 2023 | Amphetamine

Association of Pharmacological Treatments and Hospitalization and Death in Individuals With Amphetamine Use Disorders in a Swedish Nationwide Cohort of 13 965 Patients. Heikkinen M, Taipale H, Tanskanen A, Mittendorfer-Rutz E, Lähteenvuo M,...

The impact of benzodiazepine exposure on treatment retention in an open-access methadone program: A retrospective cohort study.

30. April 2023 | Benzodiazepine

The impact of benzodiazepine exposure on treatment retention in an open-access methadone program: A retrospective cohort study. Morford KL, Tetrault JM, Zhou B, Li F, Gleeson B, Edelman EJ, Stein MD, Barry DT, Madden L. Drug Alcohol ...

Online-Befragung zu Z-Substanzen und Benzodiazepinen – Teilnehmende gesucht!

21. April 2023 | Benzodiazepine

Online-Befragung zu Z-Substanzen und Benzodiazepinen – Teilnehmende gesucht! Das Institut für Medizinische Psychologie des Universitätsklinikums Hamburg-Eppendorf und das Zentrum für Interdisziplinäre Suchtforschung der Universität Hamburg (ZIS) ...

Fachgesellschaften entwickeln Hilfskonzept für Rauchstopp

21. April 2023 | Nikotin

Fachgesellschaften entwickeln Hilfskonzept für Rauchstopp Berlin – Mehr Hilfestellung beim Rauchstopp und eine entsprechende Finanzierung. Das hat die Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin (DGP) angemahnt. Sie hat auch ein ei...

"Könnten zusätzliche 40 Prozent der Patienten vom Tabak entwöhnen“ – Pneumologen fordern Finanzierung passender Angebote

21. April 2023 | Nikotin

"Könnten zusätzliche 40 Prozent der Patienten vom Tabak entwöhnen“ – Pneumologen fordern Finanzierung passender Angebote Die Deutschen rauchen zu viel: 35 Prozent der Bevölkerung greift aktuell zum Tabak und verursacht durch Folgekrankheiten mitt...

US could soon approve MDMA therapy — opening an era of psychedelic medicine

21. April 2023 | Amphetamine

US could soon approve MDMA therapy — opening an era of psychedelic medicine Perceptions have shifted dramatically in the past few years on the therapeutic value of illicit drugs such as ecstasy. But questions still linger about what FDA approval ...

Aufnahme der Pregabalinkonsumstörung in die ICD-10-GM Version 2023

21. April 2023 | Gabapentinoide

Aufnahme der Pregabalinkonsumstörung in die ICD-10-GM Version 2023 Seit Jahren steigt der missbräuchliche Konsum von Pregabalin, vor allem bei Drogenabhängigen deutlich an. Im klinischen Alltag war es bislang schwierig, das korrekt zu diagn...

Abhängigkeitspotenzial von Pregabalin

21. April 2023 | Gabapentinoide

Abhängigkeitspotenzial von Pregabalin Zusammenfassung Pregabalin wird angewendet zur Behandlung neuropathischer Schmerzen, bei generalisierter Angststörung sowie als Zusatztherapie bei partiellen epileptischen Anfällen. In epidemiologischen Stud...

Drug Information

21. April 2023 | Verschiedene

Drug Information Detailed, evidence-based information on drugs and their properties, applications, effects and risks. Based on the latest pharmacological research. (drugscience.org, UK, Stand 20.04.2023) https://www.drugscience.org.uk/drug-infor...

Malignant Catatonia Induced by Concurrent Opioid and Benzodiazepine Withdrawal.

09. April 2023 | Benzodiazepine

Malignant Catatonia Induced by Concurrent Opioid and Benzodiazepine Withdrawal. Sayles BD, Royer EG, Meyer VM, Balasanova AA. Prim Care Companion CNS Disord. 2023 Mar 16;25(2):22cr03346. doi: 10.4088/PCC.22cr03346. PMID: 36946574. h...

Examining associations between MDMA/ecstasy and classic psychedelic use and impairments in social functioning in a U.S. adult sample.

09. April 2023 | Amphetamine

Examining associations between MDMA/ecstasy and classic psychedelic use and impairments in social functioning in a U.S. adult sample. Jones, G., Lipson, J. & Wang, E. Sci Rep 13, 2466 (2023). doi.org/10.1038/s41598-023-29763...

Pregabalin Use/Misuse: A Source of Consternation in Western Punjab.

09. April 2023 | Gabapentinoide

Pregabalin Use/Misuse: A Source of Consternation in Western Punjab. Aneja J, Singh J. Indian J Psychol Med. 2023 Mar;45(2):206-207. doi: 10.1177/02537176221122389. Epub 2022 Sep 11. PMID: 36925504; PMCID: PMC10011841. https://www.nc...

Verschreibungen von Cannabisarzneimitteln 2019–2022

09. April 2023 | Cannabis als Medizin

Verschreibungen von Cannabisarzneimitteln 2019–2022 Ein Vergleich der Daten des Bundesinstituts für Arzneimittel und Medizinprodukte und der Barmer Ersatzkasse Prescriptions of cannabinoid drugs, 2019–2022—a comparison of data from the German Fe...

Clinical Practice Guidelines for Cannabis and Cannabinoid-Based Medicines in the Management of Chronic Pain and Co-Occurring Conditions.

09. April 2023 | Cannabis als Medizin

Clinical Practice Guidelines for Cannabis and Cannabinoid-Based Medicines in the Management of Chronic Pain and Co-Occurring Conditions. Bell AD, MacCallum C, Margolese S, Walsh Z, Wright P, Daeninck PJ, Mandarino E, Lacasse G, Kaur Deol J,...

Tragende Gründe zum Beschluss des Gemeinsamen Bundesausschusses über eine Änderung der Arzneimittel-Richtlinie: § 4a und Abschnitt N §§ 44 bis 45 (Cannabisarzneimittel)

09. April 2023 | Cannabis als Medizin

Tragende Gründe zum Beschluss des Gemeinsamen Bundesausschusses über eine Änderung der Arzneimittel-Richtlinie: § 4a und Abschnitt N §§ 44 bis 45 (Cannabisarzneimittel) GBA – Gemeinsamer Bundesausschuss, 16.03.2023 https://www.g-ba.de/downloads/...

Marijuana-derived compounds could reverse opioid overdoses

09. April 2023 | Cannabis als Medizin

Marijuana-derived compounds could reverse opioid overdoses There's been a recent push in the U.S. to make naloxone—a fast-acting opioid antidote—available without a prescription. This medication has saved lives, but it's less effective against po...

Recreational marijuana policies have mixed effects on opioid use, may affect other substance use patterns

09. April 2023 | Cannabis als Rauschmittel

Recreational marijuana policies have mixed effects on opioid use, may affect other substance use patterns Most states have adopted marijuana policies that allow for medicinal and/or recreational use. Some prior research suggests such policies may...

UK. RADAR Alert 2023/04, Nitazene type drugs in Scotland

09. April 2023 | Verschiedene

UK. RADAR Alert 2023/04, Nitazene type drugs in Scotland There is an increase in the availability of a new type of synthetic opioid called nitrazenes. Due to their unexpected presence they pose a substantial risk of overdose, hospitalisation and ...

Internationale Studie bestätigt langfristige Sicherheit von Methylphenidat bei Kindern und Jugendlichen mit ADHS

09. April 2023 | Verschiedene

Internationale Studie bestätigt langfristige Sicherheit von Methylphenidat bei Kindern und Jugendlichen mit ADHS Ein internationales Forscherteam hat festgestellt, dass das am häufigsten verschriebene Medikament zur Behandlung der Aufmerksamkeits...

Attention-deficit/hyperactivity disorder medication consumption in 64 countries and regions from 2015 to 2019: A longitudinal study

09. April 2023 | Verschiedene

Attention-deficit/hyperactivity disorder medication consumption in 64 countries and regions from 2015 to 2019: A longitudinal study Chan, Adrienne Y.L. et al. eClinicalMedicine, Volume 0, Issue 0, 101780 https://www.thelancet.com/jou...

UNODC. Global report on Cocaine 2023 – Local dynamics, global challenges

09. April 2023 | Kokain

UNODC. Global report on Cocaine 2023 – Local dynamics, global challenges United Nations Publications, March 2023 https://www.unodc.org/documents/data-and-analysis/cocaine/Global_cocaine_report_2023.pdf

Association Between Daily Alcohol Intake and Risk of All-Cause Mortality: A Systematic Review and Meta-analyses.

09. April 2023 | Alkohol

Association Between Daily Alcohol Intake and Risk of All-Cause Mortality: A Systematic Review and Meta-analyses. Zhao J, Stockwell T, Naimi T, Churchill S, Clay J, Sherk A. JAMA Netw Open. 2023;6(3):e236185. doi:10.1001/jamanetwo...

Alcoholic Beverage Preference in Germany: An Age-Period-Cohort Analysis of Trends 1995–2018

09. April 2023 | Alkohol

Alcoholic Beverage Preference in Germany: An Age-Period-Cohort Analysis of Trends 1995–2018 Nicolas Wilms, Nicki-Nils Seitz, Larissa Schwarzkopf, Sally Olderbak, Ludwig Kraus, Alcohol and Alcoholism, 2023;, agad013, doi.org/10.1093/al...

Exercise-induced euphoria and anxiolysis do not depend on endogenous opioids in humans.

09. April 2023 | Opioide

Exercise-induced euphoria and anxiolysis do not depend on endogenous opioids in humans. Siebers M, Biedermann SV, Bindila L, Lutz B, Fuss J. Psychoneuroendocrinology. 2021 Apr;126:105173. doi: 10.1016/j.psyneuen.2021.105173. Epu...

Exercise-induced euphoria and anxiolysis do not depend on endogenous opioids in humans.

09. April 2023 | Cannabis als Medizin

Exercise-induced euphoria and anxiolysis do not depend on endogenous opioids in humans.

09. April 2023 | Cannabis als Rauschmittel

Fentanyl-driven acceleration of racial, gender and geographical disparities in drug overdose deaths in the United States.

09. April 2023 | Fentanyl

Fentanyl-driven acceleration of racial, gender and geographical disparities in drug overdose deaths in the United States. D'Orsogna MR, Böttcher L, Chou T. PLOS Glob Public Health. 2023 Mar 22;3(3):e0000769. doi: 10.1371/journal.pgph...

Alprazolam misuse: Analysis of French Addictovigilance Network data from 2011 to 2020.

19. März 2023 | Benzodiazepine

Alprazolam misuse: Analysis of French Addictovigilance Network data from 2011 to 2020. Diaz L, Eiden C, Jouanjus E, Frauger E, Fouilhé N, Djezzar S, Gibaja V, Boucher A, Le Boisselier R, Libert F, Caous AS, Monzon E, Guerlais M, Daveluy A, ...

G-BA passt Regeln für medizinisches Cannabis an

19. März 2023 | Cannabis als Medizin

G-BA passt Regeln für medizinisches Cannabis an Berlin – Der Gemeinsame Bundesausschuss (G-BA) hat heute in Berlin Änderungen bei der Verordnung von medizinischem Cannabis beschlossen. Ein Facharztvorbehalt wurde nicht eingeführt, dafür bleibt de...

Webinar. Treatment Considerations in the Age of Fentanyl

19. März 2023 | Fentanyl

Webinar. Treatment Considerations in the Age of Fentanyl Fentanyl and other high-potency synthetic opioids are increasingly present in the U.S. drug supply. Healthcare systems, treatment providers, and justice systems are grappling with the...

Hebrew University Prof. Raphael Mechoulam “Father of Cannabis Research” Dies at 92

12. März 2023 | Cannabis als Rauschmittel

Hebrew University Prof. Raphael Mechoulam “Father of Cannabis Research” Dies at 92 March 10, 2023 — American Friends of the Hebrew University today announces the passing of the world pioneer in cannabis research, Prof. Raphael Mechoulam. Known as...

Hebrew University Prof. Raphael Mechoulam “Father of Cannabis Research” Dies at 92

12. März 2023 | Cannabis als Medizin

Xylazine: What Does the Emergence of this New Contaminant Mean for People Who Use Drugs and Health Care Providers?

12. März 2023 | Verschiedene

Xylazine: What Does the Emergence of this New Contaminant Mean for People Who Use Drugs and Health Care Providers? Throughout the past year, a substance called xylazine has been saturating the drug supply in many parts of the United States. Xylaz...

IACM: Raphael Mechoulam im Alter von 92 Jahren verstorben

12. März 2023 | Cannabis als Medizin

IACM: Raphael Mechoulam im Alter von 92 Jahren verstorben Am 9. März 2023 ist Raphael Mechoulam, emeritierter Professor für medizinische Chemie an der hebräischen Universität in Jerusalem, im Alter von 92 Jahren in seinem Haus in Jerusalem versto...

IACM: Raphael Mechoulam im Alter von 92 Jahren verstorben

12. März 2023 | Cannabis als Rauschmittel

Comparing the effects of medical cannabis for chronic pain patients with and without co-morbid anxiety: A cohort study.

12. März 2023 | Cannabis als Medizin

Comparing the effects of medical cannabis for chronic pain patients with and without co-morbid anxiety: A cohort study. Bapir L, Erridge S, Nicholas M, Pillai M, Dalavaye N, Holvey C, Coomber R, Hoare J, Khan S, Weatherall MW, Rucker JJ, Pl...

An observational study of safety and clinical outcome measures across patient groups in the United Kingdom Medical Cannabis Registry.

12. März 2023 | Cannabis als Medizin

An observational study of safety and clinical outcome measures across patient groups in the United Kingdom Medical Cannabis Registry. Olsson F, Erridge S, Tait J, Holvey C, Coomber R, Beri S, Hoare J, Khan S, Weatherall MW, Platt M, Rucker ...

CANNA-TICS: Efficacy and safety of oral treatment with nabiximols in adults with chronic tic disorders - Results of a prospective, multicenter, randomized, double-blind, placebo controlled, phase IIIb superiority study.

12. März 2023 | Cannabis als Medizin

CANNA-TICS: Efficacy and safety of oral treatment with nabiximols in adults with chronic tic disorders - Results of a prospective, multicenter, randomized, double-blind, placebo controlled, phase IIIb superiority study. Müller-Vahl KR, Pisa...

Entzündliche Darmerkrankungen: Kann Cannabis das Sterberisiko senken?

12. März 2023 | Cannabis als Medizin

Entzündliche Darmerkrankungen: Kann Cannabis das Sterberisiko senken? Philadelphia – US-Patienten mit Morbus Crohn oder Colitis ulcerosa, die zur Behandlung anderer Erkrankungen Cannabis konsumierten, hatten in einer retrospektiven Studie, deren ...

The impact of recreational cannabis markets on motor vehicle accident, suicide, and opioid overdose fatalities.

12. März 2023 | Cannabis als Rauschmittel

The impact of recreational cannabis markets on motor vehicle accident, suicide, and opioid overdose fatalities. Marinello S, Powell LM. Soc Sci Med. 2023 Mar;320:115680. doi: 10.1016/j.socscimed.2023.115680. Epub 2023 Jan 16. PMID: 3...

Cannabis legalization and cannabis use, daily cannabis use and cannabis-related problems among adults in Ontario, Canada (2001-2019).

12. März 2023 | Cannabis als Rauschmittel

Cannabis legalization and cannabis use, daily cannabis use and cannabis-related problems among adults in Ontario, Canada (2001-2019). Imtiaz S, Nigatu YT, Ali F, Douglas L, Hamilton HA, Rehm J, Rueda S, Schwartz RM, Wells S, Elton-Marshall ...

The acute effects of cannabis with and without cannabidiol in adults and adolescents: A randomised, double-blind, placebo-controlled, crossover experiment.

12. März 2023 | Cannabis als Rauschmittel

The acute effects of cannabis with and without cannabidiol in adults and adolescents: A randomised, double-blind, placebo-controlled, crossover experiment. Lawn, W, Trinci, K, Mokrysz, C, Borissova, A, Ofori, S, Pet...

The acute effects of cannabis with and without cannabidiol in adults and adolescents: A randomised, double-blind, placebo-controlled, crossover experiment.

12. März 2023 | Cannabis als Medizin

Crystal methamphetamine use and methadone maintenance treatment dissatisfaction: A prospective cohort study in Vancouver, Canada.

05. März 2023 | Amphetamine

Crystal methamphetamine use and methadone maintenance treatment dissatisfaction: A prospective cohort study in Vancouver, Canada. Cui Z, Hayashi K, Bach P, Milloy MJ, Kerr T. J Subst Use Addict Treat. 2023 Jan 18:208956. doi: 10.1016...

Mitragyna speciosa (Kratom) poisoning: Findings from ten cases.

05. März 2023 | Verschiedene

Mitragyna speciosa (Kratom) poisoning: Findings from ten cases. Peran D, Stern M, Cernohorsky P, Sykora R, Popela S, Duska F. Toxicon. 2023 Feb 15;225:107054. doi: 10.1016/j.toxicon.2023.107054. Epub ahead of print. PMID: 36801215. ...

A randomized controlled trial on the seeds of Sophora alopecuroides var. alopecuroides for the treatment of acute heroin withdrawal syndrome.

05. März 2023 | Opioide

A randomized controlled trial on the seeds of Sophora alopecuroides var. alopecuroides for the treatment of acute heroin withdrawal syndrome. Hashem-Dabaghian F, Kianbakht S. Complement Ther Clin Pract. 2023 Feb 18;51:101740. doi: 10...

New Synthetic Opioids: Clinical Considerations and Dangers.

05. März 2023 | Opioide

New Synthetic Opioids: Clinical Considerations and Dangers. Edinoff AN, Martinez Garza D, Vining SP, Vasterling ME, Jackson ED, Murnane KS, Kaye AM, Fair RN, Torres YJL, Badr AE, Cornett EM, Kaye AD. Pain Ther. 2023 Feb 24:1–23. doi:...

Anhedonia modulates benzodiazepine and opioid demand among persons in treatment for opioid use disorder.

05. März 2023 | Benzodiazepine

Anhedonia modulates benzodiazepine and opioid demand among persons in treatment for opioid use disorder. Greenwald MK, Moses TEH, Lundahl LH, Roehrs TA. Front Psychiatry. 2023 Jan 19;14:1103739. doi: 10.3389/fpsyt.2023.1103739. PMID:...

Adverse outcomes associated with concurrent gabapentin, opioid, and benzodiazepine utilization: A nested case-control study.

05. März 2023 | Benzodiazepine

Adverse outcomes associated with concurrent gabapentin, opioid, and benzodiazepine utilization: A nested case-control study. Olopoenia A, Camelo-Castillo W, Qato DM, Adekoya A, Palumbo F, Sera L, Simoni-Wastila L. Lancet Reg Health A...

Adverse outcomes associated with concurrent gabapentin, opioid, and benzodiazepine utilization: A nested case-control study.

05. März 2023 | Gabapentinoide

Clinical Impact of the CYP2C19 Gene on Diazepam for the Management of Alcohol Withdrawal Syndrome.

05. März 2023 | Benzodiazepine

Clinical Impact of the CYP2C19 Gene on Diazepam for the Management of Alcohol Withdrawal Syndrome. Ho TT, Noble M, Tran BA, Sunjic K, Gupta SV, Turgeon J, Crutchley RD. J Pers Med. 2023 Feb 3;13(2):285. doi: 10.3390/jpm1302...

Impacts of medical and non-medical cannabis on the health of older adults: Findings from a scoping review of the literature.

05. März 2023 | Cannabis als Rauschmittel

Impacts of medical and non-medical cannabis on the health of older adults: Findings from a scoping review of the literature. Wolfe D, Corace K, Butler C, Rice D, Skidmore B, Patel Y, Thayaparan P, Michaud A, Hamel C, Smith A, Garber G, Pora...

Impacts of medical and non-medical cannabis on the health of older adults: Findings from a scoping review of the literature.

05. März 2023 | Cannabis als Medizin

Australien. Methamphetamin: The Tina Trial

05. März 2023 | Amphetamine

Australien. Methamphetamin: The Tina Trial The Tina Trial is a clinical trial designed to see whether mirtazapine, an antidepressant medication, can help people reduce their use of methamphetamine (ice, crystal meth). Two previous small tria...

Short- and Long-Term Effects of Cocaine on Enteric Neuronal Functions.

05. März 2023 | Kokain

Short- and Long-Term Effects of Cocaine on Enteric Neuronal Functions. Elfers K, Menne L, Colnaghi L, Hoppe S, Mazzuoli-Weber G. Cells. 2023 Feb 10;12(4):577. doi: 10.3390/cells12040577. PMID: 36831246; PMCID: PMC9954635. https://ww...

Cocaine regulates sensory filtering in cortical pyramidal neurons.

05. März 2023 | Kokain

Cocaine regulates sensory filtering in cortical pyramidal neurons. Murphy SC, Godenzini L, Guzulaitis R, Lawrence AJ, Palmer LM. Cell Rep. 2023 Feb 14;42(2):112122. doi: 10.1016/j.celrep.2023.112122. Epub ahead of print. PMID: 367909...

Genotype-by-diagnosis interaction influences self-control in human cocaine addiction.

05. März 2023 | Kokain

Genotype-by-diagnosis interaction influences self-control in human cocaine addiction. Graczyk MM, Sahakian BJ, Robbins TW, Ersche KD. Transl Psychiatry. 2023 Feb 11;13(1):51. doi: 10.1038/s41398-023-02347-z. PMID: 36774338; PMCID: PM...

Warum psychedelische Drogen Depressionen anders lindern

02. März 2023 | Verschiedene

Warum psychedelische Drogen Depressionen anders lindern Davis/Kalifornien – Psychedelische Drogen wie Psilocybin, die in klinischen Studien bei ausgewählten Patienten eine Major-Depression rasch gelindert haben, aktivieren im Gegensatz zu den kla...

The Promise and Perils of Psychedelics

24. Februar 2023 | Verschiedene

The Promise and Perils of Psychedelics February 23, 2023, N Engl J Med 2023; 388:e24, DOI: 10.1056/NEJMp2300936 In this episode of “Intention to Treat,” a study participant and a long-time investigator of hallucinogenic drugs for psychiatric con...

Advisory: Cannabidiol (CBD) – Potential Harms, Side Effects, and Unknowns

24. Februar 2023 | Cannabis als Medizin

Advisory: Cannabidiol (CBD) – Potential Harms, Side Effects, and Unknowns This advisory introduces readers to cannabidiol (CBD), how it is derived, and how it differs from delta-9 THC and other cannabinoids. The advisory focuses on the risks and ...

Advisory: Cannabidiol (CBD) – Potential Harms, Side Effects, and Unknowns

24. Februar 2023 | Cannabis als Rauschmittel

Fentanyl Facts and Overdose Risk: A DEA Educational Foundation Course

23. Februar 2023 | Fentanyl

Fentanyl Facts and Overdose Risk: A DEA Educational Foundation Course Welcome to our course on Fentanyl Facts and Increased Overdose Risk. This course was developed by the Addiction Policy Forum in partnership with the Drug Enforcement Admi...

Trendspotter-Bericht 001: Crack, Dezember 2021 (Update) (IFT News, München, 2023)

18. Februar 2023 | Kokain

Trendspotter-Bericht 001: Crack, Dezember 2021 (Update) (IFT News, München, 2023) https://mindzone.info/wp-content/uploads/2022/03/mindzone-NEWS-Trendspotter-Bericht-Crack-in-Deutschland-2021-12-09.pdf

USA. Fentanyl Facts and Overdose Risk: An Addiction Policy Forum Course

18. Februar 2023 | Fentanyl

USA. Fentanyl Facts and Overdose Risk: An Addiction Policy Forum Course This course (20 Minuten, Anm. Forum Substitutionspraxis) was developed by the Addiction Policy Forum and JCOIN to share facts about fentanyl in the U.S., increasing ove...

Chronic escitalopram in healthy volunteers has specific effects on reinforcement sensitivity: a double-blind, placebo-controlled semi-randomised study.

15. Februar 2023 | Verschiedene

Chronic escitalopram in healthy volunteers has specific effects on reinforcement sensitivity: a double-blind, placebo-controlled semi-randomised study. Langley, C., Armand, S., Luo, Q. et al. Neuropsychopharmacol. (2023). doi.org...

State Cannabis Legalization and Psychosis-Related Health Care Utilization.

15. Februar 2023 | Cannabis als Rauschmittel

State Cannabis Legalization and Psychosis-Related Health Care Utilization. Elser H, Humphreys K, Kiang MV, et al. JAMA Netw Open. 2023;6(1):e2252689. doi:10.1001/jamanetworkopen.2022.5268 https://jamanetwork.com/journals/jamanetworkopen/fu...

Study first to show statewide cannabis-related deaths in Florida

15. Februar 2023 | Cannabis als Rauschmittel

Study first to show statewide cannabis-related deaths in Florida (…) Researchers from Florida Atlantic University's Christine E. Lynn College of Nursing are the first to conduct a statewide analysis of deaths in Florida associated with canna...

Cannabinoids and synthetic cannabinoids as a cause of death: Trends and their healthcare implications.

15. Februar 2023 | Cannabis als Rauschmittel

Cannabinoids and synthetic cannabinoids as a cause of death: Trends and their healthcare implications. Suriaga A, Tappen RM, Aston ER, Chiang-Hanisko L, Newman D. J Nurs Scholarsh. 2022 Oct 17. doi: 10.1111/jnu.12817. Epub ahead of p...

UNODC. NPS Data Visualisations

15. Februar 2023 | Neue Psychoaktive Substanzen

UNODC. NPS Data Visualisations We are pleased to announce a new, interactive feature of the UNODC Early Warning Advisory (EWA) - the Summary Dashboard - that allows to quickly explore and visualize the new psychoactive substances (NPS) data avail...

DNA methylation in cocaine use disorder–An epigenome-wide approach in the human prefrontal cortex.

15. Februar 2023 | Kokain

DNA methylation in cocaine use disorder–An epigenome-wide approach in the human prefrontal cortex. Poisel E, Zillich L, Streit F, Frank J, Friske MM, Foo JC, Mechawar N, Turecki G, Hansson AC, Nöthen MM, Rietschel M, Spanagel R and Witt SH ...

MicroRNA–mRNA networks are dysregulated in opioid use disorder postmortem brain: Further evidence for opioid-induced neurovascular alterations.

15. Februar 2023 | Opioide

MicroRNA–mRNA networks are dysregulated in opioid use disorder postmortem brain: Further evidence for opioid-induced neurovascular alterations. Grimm SL, Mendez EF, Stertz L, Meyer TD, Fries GR, Gandhi T, Kanchi R, Selvaraj S, Teixeira AL, ...

The life and times of endogenous opioid peptides: Updated understanding of synthesis, spatiotemporal dynamics, and the clinical impact in alcohol use disorder.

07. Februar 2023 | Alkohol

The life and times of endogenous opioid peptides: Updated understanding of synthesis, spatiotemporal dynamics, and the clinical impact in alcohol use disorder. Margolis EB, Moulton MG, Lambeth PS, O'Meara MJ. Neuropharmacology. 2023 ...

Illicit Non-Pharmaceutical Fentanyl and Its Analogs: A Short Review of Literature.

07. Februar 2023 | Fentanyl

Illicit Non-Pharmaceutical Fentanyl and Its Analogs: A Short Review of Literature. Velagapudi V, Sethi R. Kans J Med. 2023 Jan 18;16:25-27. doi: 10.17161/kjm.vol16.18555. PMID: 36703950; PMCID: PMC9872502. https://www.ncbi.nlm.nih.g...

Opioid Use Disorder from Poppy Seed Tea Use: A Case Report.

07. Februar 2023 | Opioide

Opioid Use Disorder from Poppy Seed Tea Use: A Case Report. Kauppila GR, Eagen KV. Am J Case Rep. 2023 Jan 26;24:e938675. doi: 10.12659/AJCR.938675. PMID: 36698302. https://amjcaserep.com/abstract/full/idArt/938675

Cocaine-Induced Time-Dependent Alterations in Cytochrome P450 and Liver Function.

07. Februar 2023 | Kokain

Cocaine-Induced Time-Dependent Alterations in Cytochrome P450 and Liver Function. Jastrzębska J, Daniel WA. Int J Mol Sci. 2023 Jan 13;24(2):1632. doi: 10.3390/ijms24021632. PMID: 36675146; PMCID: PMC9866935. https://www.ncbi.nlm.ni...

Hallucinations and Hallucinogens: Psychopathology or Wisdom?

07. Februar 2023 | Verschiedene

Hallucinations and Hallucinogens: Psychopathology or Wisdom? Bouso JC, Ona G, Kohek M, Dos Santos RG, Hallak JEC, Alcázar-Córcoles MÁ, Obiols-Llandrich J. Cult Med Psychiatry. 2023 Jan 12:1–29. doi: 10.1007/s11013-022-09814-0. Epub a...

Historical Pathways for Opioid Addiction, Withdrawal with Traditional and Alternative Treatment Options with Ketamine, Cannabinoids, and Noribogaine: A Narrative Review.

07. Februar 2023 | Verschiedene

Historical Pathways for Opioid Addiction, Withdrawal with Traditional and Alternative Treatment Options with Ketamine, Cannabinoids, and Noribogaine: A Narrative Review. Edinoff AN, Wu NW, Nix CA, Bonin B, Mouhaffel R, Vining S, Gibson W, C...

Psilocybin for Depression: From Credibility to Feasibility, What's Missing?

07. Februar 2023 | Verschiedene

Psilocybin for Depression: From Credibility to Feasibility, What's Missing? Munafò A, Arillotta D, Mannaioni G, Schifano F, Bernardini R, Cantarella G. Pharmaceuticals (Basel). 2022 Dec 31;16(1):68. doi: 10.3390/ph16010068. PMID: 366...

Gabapentinoid Prescribing Practices at a Large Academic Medical Center.

07. Februar 2023 | Gabapentinoide

Gabapentinoid Prescribing Practices at a Large Academic Medical Center. Huang LL, Wright JA, Fischer KM, Croghan IT, Nanda S, Schroeder DR, Vincent A. Mayo Clin Proc Innov Qual Outcomes. 2023 Jan 11;7(1):58-68. doi: 10.1016/j.mayocpi...

GABAA receptor subtypes and benzodiazepine use, misuse, and abuse.

07. Februar 2023 | Benzodiazepine

GABAA receptor subtypes and benzodiazepine use, misuse, and abuse. Engin E. Front Psychiatry. 2023 Jan 12;13:1060949. doi: 10.3389/fpsyt.2022.1060949. PMID: 36713896; PMCID: PMC9879605. https://www.ncbi.nlm.nih.gov/pmc/articles...

Just Say KNOW: Fentanyl, Fakery & the New Drug Talk.

07. Februar 2023 | Fentanyl

Just Say KNOW: Fentanyl, Fakery & the New Drug Talk. Ed, Ternan M. Mo Med. 2022 Nov-Dec;119(6):487-488. PMID: 36588636; PMCID: PMC9762230. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762230/

Wooden chest syndrome: A curious case of fentanyl induced rigidity in adults.

07. Februar 2023 | Fentanyl

Wooden chest syndrome: A curious case of fentanyl induced rigidity in adults. Baruah U, Gaur H, Saigal D, Pandey D. Indian J Anaesth. 2022 Dec;66(12):881-882. doi: 10.4103/ija.ija_171_22. Epub 2022 Dec 20. PMID: 36654889; PMCID: PMC9...

Atypical Fentanyl Transdermal Patch Consumption and Fatalities: Case Report and Literature Review.

07. Februar 2023 | Fentanyl

Atypical Fentanyl Transdermal Patch Consumption and Fatalities: Case Report and Literature Review. Manetti F, David MC, Gariglio S, Consalvo F, Padovano M, Scopetti M, Grande A, Santurro A. Toxics. 2022 Dec 31;11(1):46. doi: 10.3390/...

Nutzen und Schaden von Cannabisarzneimitteln aus Sicht von Patienten mit chronischen Schmerzen und ihren Ärzten : Eine Kohortenstudie in drei saarländischen Schmerzzentren

07. Februar 2023 | Cannabis als Medizin

Nutzen und Schaden von Cannabisarzneimitteln aus Sicht von Patienten mit chronischen Schmerzen und ihren Ärzten : Eine Kohortenstudie in drei saarländischen Schmerzzentren [Benefits and harms of cannabis-based medicines from the viewpoint of pati...

Amphetamines modulate fentanyl-depressed respiration in a bidirectional manner.

07. Februar 2023 | Amphetamine

Amphetamines modulate fentanyl-depressed respiration in a bidirectional manner. Elder HJ, Varshneya NB, Walentiny DM, Beardsley PM. Drug Alcohol Depend. 2023 Feb 1;243:109740. doi: 10.1016/j.drugalcdep.2022.109740. Epub 2022 Dec 16. ...

Splice-Site Variants in the Gene Encoding GABA-A Receptor Delta Subunit Are Associated with Amphetamine Use in Patients under Methadone Maintenance Treatment.

07. Februar 2023 | Amphetamine

Splice-Site Variants in the Gene Encoding GABA-A Receptor Delta Subunit Are Associated with Amphetamine Use in Patients under Methadone Maintenance Treatment. Lin YF, Chou WH, Liu TH, Fang CP, Kuo HW, Kuo PH, Tsai SJ, Wang SC, Chung RH, Tso...

Reduced neural functional connectivity during working memory performance in methamphetamine use disorder.

07. Februar 2023 | Amphetamine

Reduced neural functional connectivity during working memory performance in methamphetamine use disorder. Nestor LJ, Ghahremani DG, London ED. Drug Alcohol Depend. 2023 Feb 1;243:109764. doi: 10.1016/j.drugalcdep.2023.109764. Epub 20...

Recreational marijuana policies have mixed effects on opioid use, may affect other substance use patterns

31. Januar 2023 | Cannabis als Medizin

Recreational marijuana policies have mixed effects on opioid use, may affect other substance use patterns

31. Januar 2023 | Cannabis als Rauschmittel

Creating a safer fentanyl. How researchers are making the deadly drug less addictive

31. Januar 2023 | Fentanyl

Creating a safer fentanyl. How researchers are making the deadly drug less addictive A group of scientists say they've created a safer version of fentanyl that could potentially diminish the drug's addictive side effects, which have resulted in a...

USA. New Potent Synthetic Opioid—N-Desethyl Isotonitazene—Proliferating Among Recreational Drug Supply in USA

31. Januar 2023 | Opioide

USA. New Potent Synthetic Opioid—N-Desethyl Isotonitazene—Proliferating Among Recreational Drug Supply in USA N-Desethyl isotonitazene is a new synthetic opioid bearing structural resemblance to isotonitazene and recently emergent nitazene ...

Schottland. RADAR Alert 2023/04, Nitazene type drugs in Scotland

31. Januar 2023 | Opioide

Schottland. RADAR Alert 2023/04, Nitazene type drugs in Scotland There is an increase in the availability of a new type of synthetic opioid called nitrazenes. Due to their unexpected presence they pose a substantial risk of overdose, hospitalisat...

Handlungsempfehlungen zum Umgang mit Crack-Konsum im Kontext der Drogen- und Suchthilfe

31. Januar 2023 | Kokain

Handlungsempfehlungen zum Umgang mit Crack-Konsum im Kontext der Drogen- und Suchthilfe Die Handlungsempfehlungen zum Umgang mit Crack-Konsum (Hrsg. akzept e.V.) sind auf der Basis der Ergebnisse des Fachtages Crack am 04.10.2022 in Frankfu...

Hochschule Koblenz untersuchte Abwasser in Koblenz und Umgebung auf Rückstände von Kokain-Konsum

31. Januar 2023 | Kokain

Hochschule Koblenz untersuchte Abwasser in Koblenz und Umgebung auf Rückstände von Kokain-Konsum Das Institut für sozialwissenschaftliche Forschung und Weiterbildung (IFW) des Fachbereichs Sozialwissenschaften der Hochschule Koblenz hat gemeinsam...

Drogen in Koblenz und Umgebung - Abwasseranalyse auf Rückstände von Kokain-Konsum

31. Januar 2023 | Kokain

Drogen in Koblenz und Umgebung - Abwasseranalyse auf Rückstände von Kokain-Konsum Prof. Dr. Winfried A. Hetger Koblenz, Institut für sozialwissenschaftliche Forschung und Weiterbildung (IFW) des Fachbereichs Sozialwissenschaften de...

The Promises and Perils of Psychedelic Health Care

16. Januar 2023 | Verschiedene

The Promises and Perils of Psychedelic Health Care Many recreational drugs known for mind-altering trips are being studied to treat depression, substance use and other disorders. Here’s what you need to know. (New York Times, USA, 05.01 2023) ht...

First-in-kind psychedelic trials to treat opioid and methamphetamine use disorders

16. Januar 2023 | Verschiedene

First-in-kind psychedelic trials to treat opioid and methamphetamine use disorders Three million people in the United States have had opioid use disorder, and another 1.5 million people have dealt with methamphetamine misuse within the last year ...

Schweiz. Nachtschatten podcast

16. Januar 2023 | Verschiedene

Schweiz. Nachtschatten podcast Zwischendurch ist ja immer mal Zeit, in was spannendes reinzuhören. Und das nicht nur, wenn wir uns z.B. wegen pandemischer Unwägbarkeiten mal wieder nicht mit Freunden treffen oder in Clubs oder auf Festivals feier...

Schottland. Managing Benzodiazepine Risk: Time for a benzo specific Intervention?

09. Januar 2023 | Benzodiazepine

Schottland. Managing Benzodiazepine Risk: Time for a benzo specific Intervention? In this blog we consider interventions for people with dependent benzodiazepine (benzos) use alongside opiate use. We consider this in the context of the Medi...

Natural Sympathomimetic Drugs: From Pharmacology to Toxicology.

09. Januar 2023 | Verschiedene

Natural Sympathomimetic Drugs: From Pharmacology to Toxicology. Costa VM, Grando LGR, Milandri E, Nardi J, Teixeira P, Mladěnka P, Remião F, On Behalf Of The Oemonom. Biomolecules. 2022 Nov 30;12(12):1793. doi: 10.3390/biom12121793. ...

USA. Tranq Dope: Animal Sedative Mixed With Fentanyl Brings Fresh Horror to U.S. Drug Zones

09. Januar 2023 | Verschiedene

USA. Tranq Dope: Animal Sedative Mixed With Fentanyl Brings Fresh Horror to U.S. Drug Zones A veterinary tranquilizer called xylazine is infiltrating street drugs, deepening addiction, baffling law enforcement and causing wounds so severe that so...

USA. Tranq Dope: Animal Sedative Mixed With Fentanyl Brings Fresh Horror to U.S. Drug Zones

09. Januar 2023 | Fentanyl

USA. Verheerender neuer Drogenmix in den USA Dealer mischen Pferdeberuhigungsmittel in Opioide

09. Januar 2023 | Verschiedene

USA. Verheerender neuer Drogenmix in den USA Dealer mischen Pferdeberuhigungsmittel in Opioide In den Vereinigten Staaten werden Drogen immer häufiger mit Xylazin versetzt, einem Narkotikum für Tiere. Die Folgen sind fürchterlich. (Spiegel ...

USA. Verheerender neuer Drogenmix in den USA Dealer mischen Pferdeberuhigungsmittel in Opioide

09. Januar 2023 | Fentanyl

Differences between users' and addiction medicine experts' harm and benefit assessments of licit and illicit psychoactive drugs: Input for psychoeducation and legalization/restriction debates.

08. Januar 2023 | Verschiedene

Differences between users' and addiction medicine experts' harm and benefit assessments of licit and illicit psychoactive drugs: Input for psychoeducation and legalization/restriction debates. Bonnet U, Specka M, Kanti AK, Scherbaum N. ...

The life and times of endogenous opioid peptides: Updated understanding of synthesis, spatiotemporal dynamics, and the clinical impact in alcohol use disorder.

08. Januar 2023 | Opioide

The life and times of endogenous opioid peptides: Updated understanding of synthesis, spatiotemporal dynamics, and the clinical impact in alcohol use disorder.

08. Januar 2023 | Alkohol

Attitudes and Difficulties Associated with Benzodiazepine Discontinuation.

08. Januar 2023 | Benzodiazepine

Attitudes and Difficulties Associated with Benzodiazepine Discontinuation. Takeshima M, Aoki Y, Ie K, Katsumoto E, Tsuru E, Tsuboi T, Inada K, Kise M, Watanabe K, Mishima K, Takaesu Y. Int J Environ Res Public Health. 2022 Nov 30;19(...

Benzodiazepine Modulation of GABAA Receptors: A Mechanistic Perspective. Biomolecules.

08. Januar 2023 | Benzodiazepine

Benzodiazepine Modulation of GABAA Receptors: A Mechanistic Perspective. Biomolecules. Goldschen-Ohm MP. 2022 Nov 30;12(12):1784. doi: 10.3390/biom12121784. PMID: 36551212; PMCID: PMC9775625. https://www.ncbi.nlm.nih.gov/p...

Gabapentinoides en indicaciones no autorizadas en la ficha técnica: ¿es necesaria una estrategia de desprescripción? [Off-label use of gabapentinoid drugs: is it necessary a deprescription strategy?].

08. Januar 2023 | Gabapentinoide

Gabapentinoides en indicaciones no autorizadas en la ficha técnica: ¿es necesaria una estrategia de desprescripción? [Off-label use of gabapentinoid drugs: is it necessary a deprescription strategy?]. Echeverría Gorriti A, Alzueta Istúriz N...

The association of gabapentin initiation and neurocognitive changes in older adults with normal cognition.

08. Januar 2023 | Gabapentinoide

The association of gabapentin initiation and neurocognitive changes in older adults with normal cognition. Oh G, Moga DC, Fardo DW, Abner EL. Front Pharmacol. 2022 Nov 25;13:910719. doi: 10.3389/fphar.2022.910719. PMID: 36506564; PMC...

More Drug Monitoring and Less CT Scans of the Brain: Gabapentin Overdose in Two Peritoneal Dialysis Patients.

08. Januar 2023 | Gabapentinoide

More Drug Monitoring and Less CT Scans of the Brain: Gabapentin Overdose in Two Peritoneal Dialysis Patients. Lehmann K, Diab S, Meyer TM, Kielstein JT, Eden G. Case Rep Nephrol Dial. 2022 Sep 26;12(3):145-149. doi: 10.1159/000525922...

Cannabis use and opioid relapse: An exploratory survival analysis of prospectively collected data.

08. Januar 2023 | Cannabis als Medizin

Cannabis use and opioid relapse: An exploratory survival analysis of prospectively collected data. Naji L, Rosic T, Sanger N, Dennis B, Hillmer A, Hudson J, Worster A, Paul J, Marsh DC, Thabane L, Samaan Z. Front Psychiatry. 2022 Nov...

Cannabis use and opioid relapse: An exploratory survival analysis of prospectively collected data.

08. Januar 2023 | Cannabis als Rauschmittel

Frankreich. Nitrous oxide abuse in France: The laughing gas epidemic takes a serious toll on health (Video)

06. Januar 2023 | Verschiedene

Frankreich. Nitrous oxide abuse in France: The laughing gas epidemic takes a serious toll on health (Video) In the last three years, nitrous oxide, often used in whipped cream canisters or as a medical anaesthetic, has become an increasingly popu...

Faktenblätter zu psycho-aktiven Substanzen

06. Januar 2023 | Verschiedene

Faktenblätter zu psycho-aktiven Substanzen (Hrsg.: Infodrog: Schweizerische Koordinations-und Fachstelle Sucht (abgefragt 05.01.2023)) https://www.infodrog.ch/de/publikationen/faktenblaetter.html

Crack & Freebase – Faktenblatt für Suchtfachpersonen

06. Januar 2023 | Kokain

Crack & Freebase – Faktenblatt für Suchtfachpersonen Infodrog (Hrsg.) (2022), Schweiz, Bern: Infodrog https://www.infodrog.ch/files/content/schadensminderung_de/2022-12_infodrog_faktenblatt_crack-freebase_de.pdf

Pharmacological evaluation and forensic case series of N-pyrrolidino etonitazene (etonitazepyne), a newly emerging 2-benzylbenzimidazole ‘nitazene’ synthetic opioid.

06. Januar 2023 | Opioide

Pharmacological evaluation and forensic case series of N-pyrrolidino etonitazene (etonitazepyne), a newly emerging 2-benzylbenzimidazole ‘nitazene’ synthetic opioid. Vandeputte, M.M., Krotulski, A.J., Walther, D. et al. Arch Toxi...

Molecular Insights and Clinical Outcomes of Drugs of Abuse Adulteration: New Trends and New Psychoactive Substances.

06. Januar 2023 | Neue Psychoaktive Substanzen

Molecular Insights and Clinical Outcomes of Drugs of Abuse Adulteration: New Trends and New Psychoactive Substances. Di Trana A, Berardinelli D, Montanari E, Berretta P, Basile G, Huestis MA, Busardò FP. Int J Mol Sci. 2022 Nov 23;23...

Synthetic opioids: a review and clinical update.

06. Januar 2023 | Opioide

Synthetic opioids: a review and clinical update. Shafi A, Berry AJ, Sumnall H, Wood DM, Tracy DK. Ther Adv Psychopharmacol. 2022 Dec 10;12:20451253221139616. doi: 10.1177/20451253221139616. PMID: 36532866; PMCID: PMC9747888. https:/...

Case report on postmortem fentanyl measurement after overdose with more than 67 fentanyl patches.

06. Januar 2023 | Fentanyl

Case report on postmortem fentanyl measurement after overdose with more than 67 fentanyl patches. Peeters LEJ, Vleut IT, Tan GE, Croes EA, Bethlehem C. Forensic Toxicol. 2022 Jan;40(1):199-203. doi: 10.1007/s11419-021-00598-3. Epub 2...

Fentanyl Overdose.

06. Januar 2023 | Fentanyl

Fentanyl Overdose. Walter K. JAMA. 2022 Dec 2. doi: 10.1001/jama.2022.22462. Epub ahead of print. PMID: 36459152. https://jamanetwork.com/journals/jama/fullarticle/2799344

Characteristics and context of fentanyl test strip use among syringe service clients in southern Wisconsin.

06. Januar 2023 | Fentanyl

Characteristics and context of fentanyl test strip use among syringe service clients in southern Wisconsin. Tilhou AS, Birstler J, Baltes A, Salisbury-Afshar E, Malicki J, Chen G, Brown R. Harm Reduct J. 2022 Dec 15;19(1):142. doi: 1...

Abuse, dependence and withdrawal associated with fentanyl and the role of its (designated) route of administration: an analysis of spontaneous reports from Europe.

06. Januar 2023 | Fentanyl

Abuse, dependence and withdrawal associated with fentanyl and the role of its (designated) route of administration: an analysis of spontaneous reports from Europe. Jobski K, Bantel C, Hoffmann F. Eur J Clin Pharmacol. 2022 Dec 16. do...

USA. Opioid-Krise in den USA - Fentanyl überschwemmt San Francisco (Video)

06. Januar 2023 | Fentanyl

USA. Opioid-Krise in den USA - Fentanyl überschwemmt San Francisco (Video) Am Golden Gate zeigt sich ein unschönes Bild: Der Konsum harter Drogen auf offener Strasse nimmt stark zu. (…) Fentanyl ist überall in Amerika angekommen. Am Golden...

Pediatric Edible Cannabis Exposures and Acute Toxicity: 2017-2021.

06. Januar 2023 | Cannabis als Rauschmittel

Pediatric Edible Cannabis Exposures and Acute Toxicity: 2017-2021. Tweet MS, Nemanich A, Wahl M. Pediatrics. 2023 Jan 3:e2022057761. doi: 10.1542/peds.2022-057761. Epub ahead of print. PMID: 36594224. https://publications.aap.org/pe...

Safety and Tolerability of Oral Cannabinoids in People Living with HIV on Long-Term ART: A Randomized, Open-Label, Interventional Pilot Clinical Trial (CTNPT 028).

06. Januar 2023 | Cannabis als Rauschmittel

Safety and Tolerability of Oral Cannabinoids in People Living with HIV on Long-Term ART: A Randomized, Open-Label, Interventional Pilot Clinical Trial (CTNPT 028). Mboumba Bouassa RS, Needham J, Nohynek D, Singer J, Lee T, Bobeuf F, Samarani S, D...

Safety and Tolerability of Oral Cannabinoids in People Living with HIV on Long-Term ART: A Randomized, Open-Label, Interventional Pilot Clinical Trial (CTNPT 028).

06. Januar 2023 | Cannabis als Medizin

USA. Immer mehr Kinder in den USA essen versehentlich Cannabisprodukte

06. Januar 2023 | Cannabis als Rauschmittel

USA. Immer mehr Kinder in den USA essen versehentlich Cannabisprodukte Washington – In den USA ist die Zahl der Vorfälle, bei denen Kinder mit Cannabis versetzte Esswaren versehentlich verzehrt haben, seit der zunehmenden Legalisierung des Raus...

Neue Behandlungsansätze: Film über Heilende Drogen auf ARTE

29. Dezember 2022 | Verschiedene

Neue Behandlungsansätze: Film über Heilende Drogen auf ARTE Dtsch Arztebl 2022; 119(51-52): A-2307 / B-1903 Verbotene Substanzen wie LSD und Psilocybin aus den „Magic Mushrooms“ gelten als vielversprechende, aber auch höchst umstrittene Ansätze ...

„Mach den Chemsex-Check!“

25. Dezember 2022 | Verschiedene

„Mach den Chemsex-Check!“ Ein spielerischer Flyer des Checkpoint BLN hilft Chemsex-User den eigenen Substanzkonsum und dessen Auswirkungen zu reflektieren. (DAH – Deutsche AIDS-Hilfe, 30.11.2022) https://profis.aidshilfe.de/hiv-beratung-aktuell/...

Higher potency of fentanyl affects addiction treatment, screening

25. Dezember 2022 | Fentanyl

Higher potency of fentanyl affects addiction treatment, screening As fentanyl-related overdose deaths continue to increase, clinicians should take note of important differences that set the drug apart from the other drugs of misuse – and the trou...

The impact of khat chewing on heart activity and rehabilitation therapy from khat addiction in healthy khat chewers.

25. Dezember 2022 | Verschiedene

The impact of khat chewing on heart activity and rehabilitation therapy from khat addiction in healthy khat chewers. Kassaw, E.A., Aboye, G.T., Yilma, D. et al. Sci Rep 12, 22083 (2022). doi.org/10.1038/s41598-022-26714-w https:...

When an obscurity becomes trend: social-media descriptions of tianeptine use and associated atypical drug use.

25. Dezember 2022 | Verschiedene

When an obscurity becomes trend: social-media descriptions of tianeptine use and associated atypical drug use. Smith KE, Rogers JM, Strickland JC, Epstein DH. Am J Drug Alcohol Abuse. 2021 Jul 4;47(4):455-466. doi: 10.1080/00952990.2021.19...

The increase in benzodiazepine-laced drugs and related risks in Canada: The urgent need for effective and sustainable solutions.

25. Dezember 2022 | Benzodiazepine

The increase in benzodiazepine-laced drugs and related risks in Canada: The urgent need for effective and sustainable solutions. Russell C, Law J, Bonn M, Rehm J, Ali F. Int J Drug Policy. 2022 Dec 16;111:103933. doi: 10.1016/j.drugp...

Electronic cigarettes for smoking cessation.

25. Dezember 2022 | Nikotin

Electronic cigarettes for smoking cessation. Hartmann-Boyce J, Lindson N, Butler AR, McRobbie H, Bullen C, Begh R, Theodoulou A, Notley C, Rigotti NA, Turner T, Fanshawe TR, Hajek P. Cochrane Database of Systematic Reviews 2022, Issu...

Methamphetamine-associated heart failure: a systematic review of observational studies

12. Dezember 2022 | Amphetamine

Methamphetamine-associated heart failure: a systematic review of observational studies Manja V, Nrusimha A, Gao Y, et al Heart, Published Online First: 01 December 2022. doi: 10.1136/heartjnl-2022-321610 https://heart.bmj.com/content/earl...

Herzinsuffizienzen durch Methkonsum nehmen weltweit und in allen Bevölkerungsschichten zu

12. Dezember 2022 | Amphetamine

Herzinsuffizienzen durch Methkonsum nehmen weltweit und in allen Bevölkerungsschichten zu Menlo Park – Immer mehr Menschen weltweit sterben an Herzinsuffizienzen, die mit dem Missbrauch von Methamphetamin („Meth“, „Crystal Meth“) assoziiert sind....

DHS. Suchtmedizinische Reihe - Band 1: ALKOHOLABHÄNGIGKEIT

11. Dezember 2022 | Alkohol

DHS. Suchtmedizinische Reihe - Band 1: ALKOHOLABHÄNGIGKEIT Der vollständig überarbeitete und aktualisierte Band 1 der Suchtmedizinischen Reihe der DHS zum Thema „Alkoholabhängigkeit“ liegt ab sofort auch als Printversion zur kostenlosen Bestellun...

Stimulant abuse as a coping strategy-Forensic and criminal consequences of stimulant abuse for neuroenhancement.

11. Dezember 2022 | Amphetamine

Stimulant abuse as a coping strategy-Forensic and criminal consequences of stimulant abuse for neuroenhancement. Dominik P, Waßmer MP, Soyka M, Franke AG. Front Public Health. 2022 Oct 28;10:1028654. doi: 10.3389/fpubh.2022.1028654. ...

Stimulant abuse as a coping strategy-Forensic and criminal consequences of stimulant abuse for neuroenhancement.

11. Dezember 2022 | Kokain

Lisdexamfetamine for the treatment of acute methamphetamine withdrawal: A pilot feasibility and safety trial.

11. Dezember 2022 | Amphetamine

Lisdexamfetamine for the treatment of acute methamphetamine withdrawal: A pilot feasibility and safety trial. Acheson LS, Ezard N, Lintzeris N, Dunlop A, Brett J, Rodgers C, Gill A, Christmass M, McKetin R, Farrell M, Shoptaw S, Siefried KJ...

Vergleich von Clomethiazol und Oxazepam im Alkoholentzug

11. Dezember 2022 | Benzodiazepine

Vergleich von Clomethiazol und Oxazepam im Alkoholentzug Rüdiger Holzbach, Philipp Droste, Tilmann Magerkurth, and Georg Juckel SUCHT 2022 68:6, 313-321 https://econtent.hogrefe.com/doi/10.1024/0939-5911/a000788

Vergleich von Clomethiazol und Oxazepam im Alkoholentzug

11. Dezember 2022 | Alkohol

Alleviation of opioid withdrawal by cannabis and delta-9-tetrahydrocannabinol: A systematic review of observational and experimental human studies.

11. Dezember 2022 | Cannabis als Medizin

Alleviation of opioid withdrawal by cannabis and delta-9-tetrahydrocannabinol: A systematic review of observational and experimental human studies. De Aquino JP, Bahji A, Gómez O, Sofuoglu M. Drug Alcohol Depend. 2022 Nov 18;241:1097...

USA: Marihuana senkt den Opioideinsatz bei Krebspatienten

11. Dezember 2022 | Cannabis als Medizin

USA: Marihuana senkt den Opioideinsatz bei Krebspatienten New York – Die Legalisierung von Marihuana, das mittlerweile in 37 US-Bundesstaaten zu medizinischen Zwecken eingesetzt werden darf, hat möglicherweise zu einem Rückgang in der Verordnung ...

Understanding motivations and use typologies of gabapentin with opioid agonist medications.

11. Dezember 2022 | Gabapentinoide

Understanding motivations and use typologies of gabapentin with opioid agonist medications. Ellis MS, Qureshi R, Buttram ME. Drug Alcohol Depend. 2022 Nov 28;242:109713. doi: 10.1016/j.drugalcdep.2022.109713. Epub ahead of print. PMID: 364...

Opioid and gabapentinoid prescriptions in England from 2015 to 2020.

11. Dezember 2022 | Gabapentinoide

Opioid and gabapentinoid prescriptions in England from 2015 to 2020. Xia Y, Forget P (2022) PLoS ONE 17(11): e0276867. doi.org/10.1371/journal.pone.0276867 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0276867

Alkoholatlas Deutschland 2022 - Riskantes Konsumverhalten unter der Lupe

11. Dezember 2022 | Alkohol

Alkoholatlas Deutschland 2022 - Riskantes Konsumverhalten unter der Lupe Der Konsum von Alkohol hat in unserer Gesellschaft eine lange Tradition. Bier, Wein und andere alkoholische Getränke sind für viele eine Selbstverständlichkeit. Das Bewussts...

Gender differences in progression to crack-cocaine use and the role of sexual and physical violence.

11. Dezember 2022 | Kokain

Gender differences in progression to crack-cocaine use and the role of sexual and physical violence. Rebelatto FP, Ornell F, Roglio VS, Sanvicente-Vieira B, Grassi-Oliveira R, Pechansky F, Kessler FHP, Schuch JB, von Diemen L. Braz J Psych...

Pharmacological Treatments for Cocaine Craving: What Is the Way Forward? A Systematic Review.

11. Dezember 2022 | Kokain

Pharmacological Treatments for Cocaine Craving: What Is the Way Forward? A Systematic Review. Lassi DLS, Malbergier A, Negrão AB, Florio L, De Aquino JP, Castaldelli-Maia JM. Brain Sci. 2022 Nov 14;12(11):1546. doi: 10.3390/brainsci1...

Role of maintenance treatment on long-term efficacy of bilateral iTBS of the prefrontal cortex in treatment-seeking cocaine addicts: A retrospective analysis.

11. Dezember 2022 | Kokain

Role of maintenance treatment on long-term efficacy of bilateral iTBS of the prefrontal cortex in treatment-seeking cocaine addicts: A retrospective analysis. Sanna A, Bini V, Badas P, Corona G, Sanna G, Marcasciano L, De Vivo MC, Diana M.&...

Lachgas (Distickstoffmonoxid, N2O) – Factsheet für Fachpersonen im Kontakt mit Konsumierenden

11. Dezember 2022 | Verschiedene

Lachgas (Distickstoffmonoxid, N2O) – Factsheet für Fachpersonen im Kontakt mit Konsumierenden Infodrog (Hrsg.) (2022), Bern: Infodrog https://www.infodrog.ch/files/content/schadensminderung_de/2022-07_DE_Faktenblatt_Lachgas_def.pdf

Colombia’s Infamous ‘Pink Cocaine’ Is on the Rise in Europe

11. Dezember 2022 | Verschiedene

Colombia’s Infamous ‘Pink Cocaine’ Is on the Rise in Europe The drug, a mix of ketamine, MDMA and pink food colouring, is being sold by a new generation of young narcos in Colombia and is increasingly being seized by authorities in Europe. (VICE,...

“Tuci”, “happy water”, “k-powdered milk” – is the illicit market for ketamine expanding?

11. Dezember 2022 | Verschiedene

“Tuci”, “happy water”, “k-powdered milk” – is the illicit market for ketamine expanding? UNODC, GLOBAL SMART UPDATE, VOLUME 2 December 2022 https://www.unodc.org/documents/scientific/Global_SMART_Update_2022_Vol.27.pdf

Ketamine triggers a switch in excitatory neuronal activity across neocortex.

11. Dezember 2022 | Verschiedene

Ketamine triggers a switch in excitatory neuronal activity across neocortex. Cichon, J., Wasilczuk, A.Z., Looger, L.L. et al. Nat Neurosci (2022). doi.org/10.1038/s41593-022-01203-5 https://www.nature.com/articles/s41593-022-012...

Exploring Psychedelics and Entactogens as Treatments for Psychiatric Disorders: Proceedings of a Workshop.

11. Dezember 2022 | Verschiedene

Exploring Psychedelics and Entactogens as Treatments for Psychiatric Disorders: Proceedings of a Workshop. National Academies of Sciences, Engineering, and Medicine. 2022. Washington, DC: The National Academies Press. doi.org/10.17226/26648. htt...

Cochrane-Review bestätigt Nutzen nikotinhaltiger E-Zigaretten

11. Dezember 2022 | Nikotin

Cochrane-Review bestätigt Nutzen nikotinhaltiger E-Zigaretten Oxford – Ein aktualisierter Cochrane-Review aus Großbritannien liefert auf Basis von 17 zusätzlichen Studien erneut Evidenz, dass die Rauchentwöhnung mit Hilfe von E-Zigaretten besser ...

On the duration of cannabis effects and the presence of THC in the body.

11. Dezember 2022 | Cannabis als Rauschmittel

On the duration of cannabis effects and the presence of THC in the body. Mørland, J., Bretteville-Jensen, A.L. and Bramness, J.G. (2022), Addiction. doi.org/10.1111/add.16080 https://onlinelibrary.wiley.com/doi/full/10.1111/add.16080

EMCDDA. Recreational use of nitrousoxide: a growing concern for Europe

24. November 2022 | Verschiedene

EMCDDA. Recreational use of nitrousoxide: a growing concern for Europe European Monitoring Centre for Drugs and Drug Addiction (2022), Publications Office of the European Union, Luxembourg. https://www.emcdda.europa.eu/system/files/public...

Hohe Hürden für Cannabisverordnung auf Kassenkosten

22. November 2022 | Cannabis als Medizin

Hohe Hürden für Cannabisverordnung auf Kassenkosten Kassel – Für die Verordnung von Cannabis zulasten der gesetzlichen Krankenversicherung (GKV) gelten hohe Anforderungen. Die Krankheit der Patienten muss sich deutlich „von durchschnittlichen Erk...

G-BA: Allgemeinmediziner sollen kein Cannabis mehr verordnen dürfen

22. November 2022 | Cannabis als Medizin

G-BA: Allgemeinmediziner sollen kein Cannabis mehr verordnen dürfen Berlin – Der Gemeinsame Bundesausschuss (G-BA) plant Änderungen bei der Regulierung von medizinischem Cannabis. In einem Stellungnahmeverfahren können Fach- und Branchenverbände ...

Does cannabidiol make cannabis safer? A randomised, double-blind, cross-over trial of cannabis with four different CBD:THC ratios.

22. November 2022 | Cannabis als Rauschmittel

Does cannabidiol make cannabis safer? A randomised, double-blind, cross-over trial of cannabis with four different CBD:THC ratios. Englund, A., Oliver, D., Chesney, E. et al. Neuropsychopharmacol. (2022). doi.org/10.1038/s41386-0...

Niederlande. Niederlande setzen Lachgas auf die Drogenliste

22. November 2022 | Verschiedene

Niederlande. Niederlande setzen Lachgas auf die Drogenliste Den Haag – Die Niederlande wollen den Besitz und den Verkauf von Lachgas verbieten. Ab dem 1. Januar 2023 solle das zur Gruppe der Stickoxide gehörende Gas auf die Liste der verbotenen R...

Major-Depression: Psilocybin erzielt in Phase-2-Studie begrenzte Wirkung

22. November 2022 | Verschiedene

Major-Depression: Psilocybin erzielt in Phase-2-Studie begrenzte Wirkung London – Die einmalige Gabe des Halluzinogens Psilocybin im Rahmen einer eintägigen Therapiesitzung kann die Symptome von Patienten mit Major-Depressionen über mehrere Woche...

USA. DEA Laboratory Testing Reveals that 6 out of 10 Fentanyl-Laced Fake Prescription Pills Now Contain a Potentially Lethal Dose of Fentanyl

22. November 2022 | Fentanyl

USA. DEA Laboratory Testing Reveals that 6 out of 10 Fentanyl-Laced Fake Prescription Pills Now Contain a Potentially Lethal Dose of Fentanyl WASHINGTON – The U.S. Drug Enforcement Administration is alerting the public of a sharp nationwide incre...

An Immunconjugate Vaccine Alters Distribution and Reduces the Antinociceptive, Behavioral and Physiological Effects of Fentanyl in Male and Female Rats

22. November 2022 | Fentanyl

An Immunconjugate Vaccine Alters Distribution and Reduces the Antinociceptive, Behavioral and Physiological Effects of Fentanyl in Male and Female Rats. Haile CN, Baker MD, Sanchez SA, Lopez Arteaga CA, Duddupudi AL, Cuny GD, Norton EB, Kos...

Fentanyl isn’t just causing overdoses. It’s making it harder to start addiction treatment

22. November 2022 | Fentanyl

Fentanyl isn’t just causing overdoses. It’s making it harder to start addiction treatment Doctors are reporting a troubling trend when it comes to fentanyl. The powerful drug, they say, isn’t just causing overdoses — it’s also making it mor...

Time to Stop Using the Word “Smoker”: Reflecting on the Role of Language in Advancing the Field of Nicotine and Tobacco Research,

12. November 2022 | Nikotin

Time to Stop Using the Word “Smoker”: Reflecting on the Role of Language in Advancing the Field of Nicotine and Tobacco Research, Renee D Goodwin, PhD, MPH, Lisa K Walker, PhD, Nicotine & Tobacco Research, 2022;, ntac218, do...

FDA alerts health care professionals of risks to patients exposed to xylazine in illicit drugs

12. November 2022 | Verschiedene

FDA alerts health care professionals of risks to patients exposed to xylazine in illicit drugs Health care professionals should be cautious of possible xylazine inclusion in fentanyl, heroin, and other illicit drug overdoses, as naloxone may not ...

Combating illicit fentanyl: Will increased Chinese regulation generate a public health crisis in India?

09. November 2022 | Fentanyl

Combating illicit fentanyl: Will increased Chinese regulation generate a public health crisis in India? Wang C, Lassi N. Front Public Health. 2022 Oct 14;10:969395. doi: 10.3389/fpubh.2022.969395. PMID: 36311594; PMCID: PMC96143...

Pro und Contra: Starken Rauchern sollten vorübergehend E-Zigaretten zum Rauchverzicht empfohlen werden

09. November 2022 | Nikotin

Pro und Contra: Starken Rauchern sollten vorübergehend E-Zigaretten zum Rauchverzicht empfohlen werden Berlin – E-Zigaretten sind ein beliebtes Mittel zum Rauchstopp. Bisher durchgeführte randomisiert kontrollierte Studien zeigen, dass E-Zigaret...

Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression.

08. November 2022 | Verschiedene

Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression. Goodwin GM, Aaronson ST, Alvarez O, Arden PC, Baker A, Bennett JC, Bird C, Blom RE, Brennan C, Brusch D, Burke L, Campbell-Coker K, Carhart-Harris R, Cattell J, D...

Cue-induced cocaine craving enhances psychosocial stress and vice versa in chronic cocaine users.

08. November 2022 | Kokain

Cue-induced cocaine craving enhances psychosocial stress and vice versa in chronic cocaine users. Kexel AK, Kluwe-Schiavon B, Baumgartner MR, Engeli EJE, Visentini M, Kirschbaum C, Seifritz E, Ditzen B, Soravia LM, Quednow BB. Transl...

The Ratio of Second and Fourth Digit Length: A Biomarker for Methamphetamine Dependence?

08. November 2022 | Amphetamine

The Ratio of Second and Fourth Digit Length: A Biomarker for Methamphetamine Dependence? Kim Y, Won SD, Kwon H, Han C. Clin Psychopharmacol Neurosci. 2022 Nov 30;20(4):694-700. doi: 10.9758/cpn.2022.20.4.694. PMID: 36263644; PMCID: P...

Risk of major adverse events associated with gabapentinoid and opioid combination therapy: A systematic review and meta-analysis.

08. November 2022 | Gabapentinoide

Risk of major adverse events associated with gabapentinoid and opioid combination therapy: A systematic review and meta-analysis. Hahn J, Jo Y, Yoo SH, Shin J, Yu YM, Ah YM. Front Pharmacol. 2022 Oct 11;13:1009950. doi: 10.3389/fphar...

Lippstädter Benzo-Check

08. November 2022 | Benzodiazepine

Lippstädter Benzo-Check Benzodiazepine und Non-Benzodiazepine (Zolpidem, Zopiclon, Zaleplon) sind gut wirksame Medikamente, die sich zur medikamentösen Behandlung von psychischen Krisen sehr gut eignen. In der Regel werden diese Medikamente zu Be...

The Pharmacogenetics of Cannabis in the Treatment of Chronic Pain.

08. November 2022 | Cannabis als Medizin

The Pharmacogenetics of Cannabis in the Treatment of Chronic Pain. Poli P, Peruzzi L, Maurizi P, Mencucci A, Scocca A, Carnevale S, Spiga O, Santucci A. Genes (Basel). 2022 Oct 11;13(10):1832. doi: 10.3390/genes13101832. PMID: 362927...

Validity of the Single-Item Screen-Cannabis (SIS-C) for Cannabis Use Disorder Screening in Routine Care.

08. November 2022 | Cannabis als Rauschmittel

Validity of the Single-Item Screen-Cannabis (SIS-C) for Cannabis Use Disorder Screening in Routine Care. Matson TE, Lapham GT, Bobb JF, Oliver M, Hallgren KA, Williams EC, Bradley KA. JAMA Netw Open. 2022 Nov 1;5(11):e2239772. doi: 1...

Impacts of recreational cannabis legalization on cannabis use: a longitudinal discordant twin study.

08. November 2022 | Cannabis als Rauschmittel

Impacts of recreational cannabis legalization on cannabis use: a longitudinal discordant twin study. Zellers, SM, Ross, JM, Saunders, GRB, Ellingson, JM, Anderson, JE, Corley, RP, et al. Addiction. 2022. doi.o...

Cannabis Use Is Inversely Associated with Metabolic Disorders in Hepatitis C-Infected Patients (ANRS CO22 Hepather Cohort).

08. November 2022 | Cannabis als Medizin

Cannabis Use Is Inversely Associated with Metabolic Disorders in Hepatitis C-Infected Patients (ANRS CO22 Hepather Cohort). Barré T, Bourlière M, Ramier C, Carrat F, Di Beo V, Protopopescu C, Marcellin F, Bureau M, Cagnot C, Dorival C, Zoul...

Hamburg, Verordnungen für den Schwarzmarkt

01. November 2022 | Gabapentinoide

Hamburg, Verordnungen für den Schwarzmarkt Ein einträgliches Geschäftsmodell ist erfolgreicher geworden: Mehr Doc-Hopper bekommen von mehr Praxen mehr Pregabalin. Auch einzelnen Patienten wird mehr verordnet R.Ullmann KVH Journal, KV Hamburg, 1...

Minimising the Harms from Methamphetamine. The Helen Clark Foundation and New Zealand Drug Foundation, Wellington.

01. November 2022 | Amphetamine

Minimising the Harms from Methamphetamine. The Helen Clark Foundation and New Zealand Drug Foundation, Wellington. Yasbek, P., Mercier K., Dr Elder, H., Dr Crossin, R., Prof. Baker, M. (2022). https://drive.google.com/file/d/1MVdFkDCr3IhMZ...

Zürich kokst - Eine Stadt auf Drogen (Podcast)

01. November 2022 | Kokain

Zürich kokst - Eine Stadt auf Drogen (Podcast) In Zürich ist Koks zur Volksdroge geworden, seit die Preise gesunken sind. In kaum einer Stadt Europas wird so viel Kokain konsumiert wie in der Finanzmetropole. Nicht legalisiert, aber akzeptiert. (...

What you need to know about 3‑MMC, the party drug of the moment

01. November 2022 | Neue Psychoaktive Substanzen

What you need to know about 3‑MMC, the party drug of the moment Last year, the drug was found in a load of the UK’s pill supply. Now, 3-MMC has been doing the rounds in the Berlin party scene. But what actually is it? (The Face, UK, 07.10.2...

‘Canberra ketamine’: new recreational drug discovered at Australian pill-testing service

01. November 2022 | Verschiedene

‘Canberra ketamine’: new recreational drug discovered at Australian pill-testing service ‘As far as we’re aware, this is the first detection of a new drug by a drug-checking service anywhere in the world,’ says professor. (The Guardian, UK, 18.10...

NPS Discovery Toolkit: N-Pyrrolidino Etonitazene

01. November 2022 | Neue Psychoaktive Substanzen

NPS Discovery Toolkit: N-Pyrrolidino Etonitazene NPS Discovery (2022), Center for Forensic Science Research and Education, United States of America. https://www.cfsre.org/images/toolkits/N-Pyrrolidino_Etonitazene_NPS_Discovery_Toolkit_221024.pdf

EMCDDA. Brochure: 25 years of monitoring and responding to new drugs in Europe

01. November 2022 | Neue Psychoaktive Substanzen

EMCDDA. Brochure: 25 years of monitoring and responding to new drugs in Europe Summary This brochure provides an overview of 25 years of the EU Early Warning System (EWS) on new psychoactive substances (NPS). Operated by the EMCDDA in close...

„Die Gesundheitsrisiken reduzieren sich auf dem legalen Markt“

11. Oktober 2022 | Cannabis als Rauschmittel

„Die Gesundheitsrisiken reduzieren sich auf dem legalen Markt“ Berlin – Abgeordnete des Gesundheitsausschusses im Bundestag haben sich bei einer Delegationsreise nach Kanada und in die Vereinigten Staaten vom 10. bis 17. September rund um Fragen ...

Cannabidiol Effect on Cue-Induced Craving for Individuals with Opioid Use Disorder Treated with Buprenorphine: A Small Proof-of-Concept Open-Label Study.

11. Oktober 2022 | Cannabis als Medizin

Cannabidiol Effect on Cue-Induced Craving for Individuals with Opioid Use Disorder Treated with Buprenorphine: A Small Proof-of-Concept Open-Label Study. Suzuki J, Martin B, Prostko S, Chai PR, Weiss RD. Integr Med Rep. 2022 Aug 1;1(...

Co-prescribing of opioids and benzodiazepines/Z-drugs associated with all-cause mortality-A population-based longitudinal study in primary care with weak opioids most commonly prescribed.

11. Oktober 2022 | Benzodiazepine

Co-prescribing of opioids and benzodiazepines/Z-drugs associated with all-cause mortality-A population-based longitudinal study in primary care with weak opioids most commonly prescribed. Linnet K, Thorsteinsdottir HS, Sigurdsson JA, Sigurd...

A review of synthetic cathinones emerging in recent years (2019-2022).

11. Oktober 2022 | Neue Psychoaktive Substanzen

A review of synthetic cathinones emerging in recent years (2019-2022). Kuropka P, Zawadzki M, Szpot P. Forensic Toxicol. 2022 Sep 15:1-22. doi: 10.1007/s11419-022-00639-5. Epub ahead of print. PMID: 36124107; PMCID: PMC9476408. http...

UNODC. Current NPS Threats, Volume V

11. Oktober 2022 | Neue Psychoaktive Substanzen

UNODC. Current NPS Threats, Volume V Over 1150 NPS from 137 countries and territories have been reported to the UNODC Early Warning Advisory on New Psychoactive Substances - Benzodiazepine-type substances continue to be a primary NPS threat, rep...

Off-label and investigational drugs in the treatment of alcohol use disorder: A critical review

11. Oktober 2022 | Alkohol

Off-label and investigational drugs in the treatment of alcohol use disorder: A critical review Fischler PV, Soyka M, Seifritz E and Mutschler J (2022) Front. Pharmacol., 03 October 2022, Sec. Neuropharmacology, doi.org/10.3389/fphar.2022.927703...

"There's No Heroin Around Anymore. It's All Fentanyl." Adaptation of an Opioid Overdose Prevention Counseling Approach to Address Fentanyl Overdose: Formative Study.

11. Oktober 2022 | Fentanyl

"There's No Heroin Around Anymore. It's All Fentanyl." Adaptation of an Opioid Overdose Prevention Counseling Approach to Address Fentanyl Overdose: Formative Study. McMahan VM, Arenander J, Matheson T, Lambert AM, Brennan S, Green TC, Wall...

Fentanyl-Themenseite von Drug Science (UK)

11. Oktober 2022 | Fentanyl

Fentanyl-Themenseite von Drug Science (UK) https://www.drugscience.org.uk/drug-information/fentanyl

A Peculiar Case of Fentanyl-Induced Cardiomyopathy.

11. Oktober 2022 | Fentanyl

A Peculiar Case of Fentanyl-Induced Cardiomyopathy. Badar F, Ashraf A, Bhuiyan MR, Bimal T, Iftikhar A. Cureus. 2022 Aug 5;14(8):e27708. doi: 10.7759/cureus.27708. PMID: 36081981; PMCID: PMC9440989. https://www.ncbi.nlm.nih.gov/pmc/...

First Known Opiate Biomarker Shows Fentanyl's Effect on the Brain

11. Oktober 2022 | Fentanyl

First Known Opiate Biomarker Shows Fentanyl's Effect on the Brain Fentanyl depresses breathing about 4 minutes before symptoms of distress are evident at a dose that is 1700 times lower than that needed for sedation, new research shows. This new...

“Rainbow Fentanyl” Is Probably a Good Thing, at This Point

11. Oktober 2022 | Fentanyl

“Rainbow Fentanyl” Is Probably a Good Thing, at This Point Kanada. When Toronto’s Moss Park Overdose Prevention Site opened as an unsanctioned service in August 2017, drug-checking data contributed by staff and participants caught the final few m...

Medical Cannabis Patients Report Improvements in Health Functioning and Reductions in Opiate Use,

11. Oktober 2022 | Cannabis als Medizin

Medical Cannabis Patients Report Improvements in Health Functioning and Reductions in Opiate Use, Carolyn E. Pritchett, Heather Flynn, Yuxia Wang & James E. Polston (2022) Substance Use & Misuse, DOI: 10.1080/10826084.2022.2107...

Pain response to cannabidiol in opioid-induced hyperalgesia, acute nociceptive pain, and allodynia using a model mimicking acute pain in healthy adults in a randomized trial (CANAB II).

11. Oktober 2022 | Cannabis als Medizin

Pain response to cannabidiol in opioid-induced hyperalgesia, acute nociceptive pain, and allodynia using a model mimicking acute pain in healthy adults in a randomized trial (CANAB II). Dieterle M, Zurbriggen L, Mauermann E, Mercer-Chalmers...

The State of Research on Cannabis as an Opioid “Exit Drug”

11. Oktober 2022 | Cannabis als Medizin

The State of Research on Cannabis as an Opioid “Exit Drug” It’s legal for adult use in 19 states, two territories and DC, and for medical use in 37 states, four territories and DC. It’s on the Nasdaq, and produced in a capitalist profusion of bra...

Häufigkeit von Nebenwirkungen bei der Therapie mit Cannabisarzneimitteln: Ergebnisse aus der Begleiterhebung des BfArM

11. Oktober 2022 | Cannabis als Medizin

Häufigkeit von Nebenwirkungen bei der Therapie mit Cannabisarzneimitteln: Ergebnisse aus der Begleiterhebung des BfArM P. CREMER-SCHAEFFER, G. SCHMIDT-WOLF (BfArM) Bulletin für Arzneimittelsicherheit, Ausgabe 3/2022, Hrsg. PEI und BfArM https:/...

Review: Cannabinoids as Medicinals.

11. Oktober 2022 | Cannabis als Medizin

Review: Cannabinoids as Medicinals. Khalsa JH, Bunt G, Blum K, Maggirwar SB, Galanter M, Potenza MN. Curr Addict Rep. 2022 Sep 7:1-17. doi: 10.1007/s40429-022-00438-3. Epub ahead of print. PMID: 36093358; PMCID: PMC9449267. https://...

Prescription opioids and longitudinal changes in cognitive function in older adults: A population-based observational study.

11. Oktober 2022 | Opioide

Prescription opioids and longitudinal changes in cognitive function in older adults: A population-based observational study. Warner, NS, Hanson, AC, Schulte, PJ, Habermann, EB, Warner, DO, Mielke, MM. J Am Geriatr ...

Israel. Earliest evidence of opium use found in burial site in Israel

11. Oktober 2022 | Opioide

Israel. Earliest evidence of opium use found in burial site in Israel Evidence of the earliest use of the narcotic opium has been found in an ancient burial site in Israel. Traces were discovered by archaeologists in pottery vessels at the compl...

Efficacy of ketamine intervention to decrease alcohol use, cravings, and withdrawal symptoms in adults with problematic alcohol use or alcohol use disorder: A systematic review and comprehensive analysis of mechanism of actions.

11. Oktober 2022 | Verschiedene

Efficacy of ketamine intervention to decrease alcohol use, cravings, and withdrawal symptoms in adults with problematic alcohol use or alcohol use disorder: A systematic review and comprehensive analysis of mechanism of actions. Garel N, Mc...

The Seeds of Ignorance - Consequences of a Booming Betel-Nut Economy.

11. Oktober 2022 | Verschiedene

The Seeds of Ignorance - Consequences of a Booming Betel-Nut Economy. Moss WJ. N Engl J Med. 2022 Sep 22;387(12):1059-1061. doi: 10.1056/NEJMp2203571. Epub 2022 Sep 17. PMID: 36121043. https://www.nejm.org/doi/full/10.1056/NEJMp2203571

Laughing gas and the scientific pursuit of the sublime

11. Oktober 2022 | Verschiedene

Laughing gas and the scientific pursuit of the sublime In September 2021, the UK Home Secretary ordered a review into possession of nitrous oxide gas, one of the most popular recreational substances among 16- to 24-year-olds. Inhaling the gas may...

Harm reduction interventions as a potential solution to managing cannabis use in people with psychosis: A call for a paradigm shift.

11. Oktober 2022 | Cannabis als Rauschmittel

Harm reduction interventions as a potential solution to managing cannabis use in people with psychosis: A call for a paradigm shift. Coronado-Montoya S, Tra C, Jutras-Aswad D. Int J Drug Policy. 2022 Aug 1;108:103814. doi: 10.1016/j.drugpo...

Can cannabis kill? Characteristics of deaths following cannabis use in England (1998–2020).

11. Oktober 2022 | Cannabis als Rauschmittel

Can cannabis kill? Characteristics of deaths following cannabis use in England (1998–2020). Rock KL, Englund A, Morley S, Rice K, Copeland CS. Journal of Psychopharmacology. 2022;0(0). doi:10.1177/02698811221115760 https://journals....

Rates and correlates of cannabis-associated psychotic symptoms in over 230,000 people who use cannabis.

11. Oktober 2022 | Cannabis als Rauschmittel

Rates and correlates of cannabis-associated psychotic symptoms in over 230,000 people who use cannabis. Schoeler T, Ferris J, Winstock AR. Transl Psychiatry. 2022 Sep 6;12(1):369. doi: 10.1038/s41398-022-02112-8. PMID: 36068202; PMCI...

Cannabinoid hyperemesis syndrome and cannabis withdrawal syndrome: a review of the management of cannabis-related syndrome in the emergency department.

11. Oktober 2022 | Cannabis als Rauschmittel

Cannabinoid hyperemesis syndrome and cannabis withdrawal syndrome: a review of the management of cannabis-related syndrome in the emergency department. Razban M, Exadaktylos AK, Santa VD, Heymann EP. Int J Emerg Med. 2022 Sep 8;15(1)...

Cocaine Use Disorder (CUD): Current Clinical Perspectives.

11. Oktober 2022 | Kokain

Cocaine Use Disorder (CUD): Current Clinical Perspectives. Schwartz EKC, Wolkowicz NR, De Aquino JP, MacLean RR, Sofuoglu M. Subst Abuse Rehabil. 2022 Sep 3;13:25-46. doi: 10.2147/SAR.S337338. PMID: 36093428; PMCID: PMC9451050. http...

The Prospects for TNX-1300, a Drug to Reverse Cocaine Overamps

11. Oktober 2022 | Kokain

The Prospects for TNX-1300, a Drug to Reverse Cocaine Overamps Amid the overdose crisis, the bulk of national attention lies on opioids like fentanyl. This has seen the opioid-overdose reversal drug naloxone become a household name, and become mo...

Cannabis use and public health: time for a comprehensive harm-to-others framework

11. Oktober 2022 | Cannabis als Rauschmittel

Cannabis use and public health: time for a comprehensive harm-to-others framework Fischer, Benedikt et al. The Lancet Public Health, Volume 7, Issue 10, e808 - e809 https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(22)00205-...

An EEG Biomarker of Fentanyl Drug Effects,

06. Oktober 2022 | Fentanyl

An EEG Biomarker of Fentanyl Drug Effects, Gustavo A Balanza, Kishore M Bharadwaj, Andrew C Mullen, Amanda M Beck, Erin C Work, Francis J McGovern, Timothy T Houle, Eric T Pierce, Patrick L Purdon, PNAS Nexus, 2022;, pgac158, doi.org...

Could Opium Gum be the Solution to the Overdose Crisis?

06. Oktober 2022 | Opioide

Could Opium Gum be the Solution to the Overdose Crisis? The prohibitionist regime surrounding the adult use of drugs has had devastating impacts on individuals, communities, and entire regions, spurring corruption, deteriorating the rule of law, ...

Dynamic recognition of naloxone, morphine and endomorphin1 in the same pocket of µ-opioid receptors.

06. Oktober 2022 | Opioide

Dynamic recognition of naloxone, morphine and endomorphin1 in the same pocket of µ-opioid receptors. Zhang X, Sun MY, Zhang X, Guo CR, Lei YT, Wang WH, Fan YZ, Cao P, Li CZ, Wang R, Li XH, Yu Y, Yang XN. Front Mol Biosci. 2022 Aug 16...

Ärzte beklagen Wartezeiten beim Antragsverfahren für medizinisches Cannabis

06. Oktober 2022 | Cannabis als Medizin

Ärzte beklagen Wartezeiten beim Antragsverfahren für medizinisches Cannabis Berlin – Für medizinische Cannabinoide ist in Deutschland vor der Verordnung ein Antragsverfahren notwendig. Schmerzmediziner beklagten heute die administrativen Hürden ...

Edible Cannabis Legalization and Unintentional Poisonings in Children

06. Oktober 2022 | Cannabis als Rauschmittel

Edible Cannabis Legalization and Unintentional Poisonings in Children Canadian data show that legalization of cannabis for adults has been associated with increased hospitalizations for unintentional cannabis poisoning in children, mostly after l...

Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder: A Randomized Clinical Trial.

06. Oktober 2022 | Verschiedene

Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder: A Randomized Clinical Trial. Bogenschutz MP, Ross S, Bhatt S, et al. JAMA Psychiat...

Depression „ausgeknipst“: So funktioniert die Therapie mit Halluzinogenen – was (Es-)ketamin und Psilocybin können und was nicht

13. September 2022 | Verschiedene

Depression „ausgeknipst“: So funktioniert die Therapie mit Halluzinogenen – was (Es-)ketamin und Psilocybin können und was nicht Neuere Studien mit Halluzinogenen haben die Hoffnung auf eine effektive medikamentöse Therapie chronischer Depression...

Novel Designer Benzodiazepines: Comprehensive Review of Evolving Clinical and Adverse Effects.

13. September 2022 | Benzodiazepine

Novel Designer Benzodiazepines: Comprehensive Review of Evolving Clinical and Adverse Effects. Edinoff AN, Nix CA, Odisho AS, Babin CP, Derouen AG, Lutfallah SC, Cornett EM, Murnane KS, Kaye AM, Kaye AD. Neurol Int. 2022 Aug 22;14(3)...

Die Rolle von Privatverordnungen bei der Versorgung mit Benzodiazepinen und Z-Drugs - Eine Sekundärdatenanalyse von Praxisdaten - The role of private prescriptions in benzodiazepine and Z-drug use—a secondary analysis of office-based prescription data

13. September 2022 | Benzodiazepine

Die Rolle von Privatverordnungen bei der Versorgung mit Benzodiazepinen und Z-Drugs - Eine Sekundärdatenanalyse von Praxisdaten - The role of private prescriptions in benzodiazepine and Z-drug use—a secondary analysis of office-based prescription ...

Deutscher Verkehrsgerichtstag empfiehlt Erhöhung des THC-Grenzwerts

23. August 2022 | Cannabis als Rauschmittel

Deutscher Verkehrsgerichtstag empfiehlt Erhöhung des THC-Grenzwerts Goslar – Der Deutsche Verkehrsgerichtstag hat dem Gesetzgeber eine Erhöhung des THC-Grenzwerts im Straßenverkehr empfohlen. Der derzeit angewandte Grenzwert solle „angemessen“ h...

USA. They Call It 'Tranq' -- and It's Making Street Drugs Even More Dangerous

23. August 2022 | Verschiedene

USA. They Call It 'Tranq' -- and It's Making Street Drugs Even More Dangerous Approaching a van that distributes supplies for safer drug use in Greenfield, Massachusetts, a man named Kyle noticed an alert about xylazine. "Xylazine?" he asked, so...

Australien. Fentanyl seizure: experts warn potent drug could rapidly emerge as a problem in Australia

23. August 2022 | Fentanyl

Australien. Fentanyl seizure: experts warn potent drug could rapidly emerge as a problem in Australia Experts say news of record haul of more than 11kg of the opioid drug, found in February, should have been announced sooner. (Guardian, UK, 22.08...

Fentanyl Purity, Potency, & Synthesis: Real-Time Testing of Opioid Drug Products in the United States

23. August 2022 | Fentanyl

Fentanyl Purity, Potency, & Synthesis: Real-Time Testing of Opioid Drug Products in the United States Krotulski, AJ, Shinefeld, J, DeBord, J, Logan, BK (2022), Center for Forensic Science Research and Education, United States of ...

What Ketamine and Psilocybin Can and Cannot Do in Depression

23. August 2022 | Verschiedene

What Ketamine and Psilocybin Can and Cannot Do in Depression Recent studies with hallucinogens have raised hopes for an effective drug-based therapy to treat chronic depression. At the German Congress of Psychosomatic Medicine and Psychotherapy, ...

Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking.

23. August 2022 | Opioide

Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking. Maza, N., Wang, D., Kowalski, C. et al. Nat Neurosci (2022). doi.org/10.1038/s41593-022-01135-0 https://www.nature.com/art...

Estimating the effects of legalizing recreational cannabis on newly incident cannabis use.

14. August 2022 | Cannabis als Rauschmittel

Estimating the effects of legalizing recreational cannabis on newly incident cannabis use. Montgomery BW, Roberts MH, Margerison CE, Anthony JC (2022) PLoS ONE 17(7): e0271720. doi.org/10.1371/journal.pone.0271720 https://journals.plos.or...

Synthetic cannabinoid poisonings and access to the legal cannabis market: findings from US national poison centre data 2016–2019,

14. August 2022 | Cannabis als Rauschmittel

Synthetic cannabinoid poisonings and access to the legal cannabis market: findings from US national poison centre data 2016–2019, Tracy A. Klein, Julia A. Dilley, Janessa M. Graves & Erica L. Liebelt (2022) Clinical Toxicology, DOI...

Legal Reponses to Novel Psychoactive Substances implemented by ten European Countries: an analysis from legal epidemiology

14. August 2022 | Neue Psychoaktive Substanzen

Legal Reponses to Novel Psychoactive Substances implemented by ten European Countries: an analysis from legal epidemiology Jessica Neicun, Andres Roman-Urrestarazu, Katarzyna Czabanowska Emerging Trends in Drugs, Addictions, and Health...

Pregabalin Toxicity-Induced Posterior Reversible Encephalopathy Syndrome.

14. August 2022 | Gabapentinoide

Pregabalin Toxicity-Induced Posterior Reversible Encephalopathy Syndrome. Hsiao F, Ma A, Muthukanagaraj P. Cureus. 2022 Jun 4;14(6):e25656. doi: 10.7759/cureus.25656. PMID: 35784981; PMCID: PMC9249023. https://www.ncbi.nlm.nih.gov/p...

Pharmacotherapies for Methamphetamine Withdrawal (Video)

14. August 2022 | Amphetamine

Pharmacotherapies for Methamphetamine Withdrawal (Video) This Video Abstract explores what we know about methamphetamine withdrawal, and how treating it might be approached. Using the results of a systematic review and meta-analysis, we discuss ...

Interaction With the Lipid Membrane Influences Fentanyl Pharmacology.

13. August 2022 | Fentanyl

Interaction With the Lipid Membrane Influences Fentanyl Pharmacology. Sutcliffe KJ, Corey RA, Alhosan N, Cavallo D, Groom S, Santiago M, Bailey C, Charlton SJ, Sessions RB, Henderson G, Kelly E. Adv Drug Alcohol Res. 2022 Mar 21;2:ad...

Benzodiazepine use and the risk of dementia.

13. August 2022 | Benzodiazepine

Benzodiazepine use and the risk of dementia. Joyce G, Ferido P, Thunell J, Tysinger B, Zissimopoulos J. Alzheimers Dement (N Y). 2022 Jul 20;8(1):e12309. doi: 10.1002/trc2.12309. PMID: 35874428; PMCID: PMC9297381. https://www.n...

Psychosocial interventions to reduce alcohol consumption in concurrent problem alcohol and illicit drug users.

13. August 2022 | Alkohol

Psychosocial interventions to reduce alcohol consumption in concurrent problem alcohol and illicit drug users. Klimas J, Fairgrieve C, Tobin H, Field CA, O'Gorman CS, Glynn LG, Keenan E, Saunders J, Bury G, Dunne C, Cullen W. Cochrane Database S...

Meta-Analysis of Structural and Functional Brain Abnormalities in Cocaine Addiction.

09. August 2022 | Kokain

Meta-Analysis of Structural and Functional Brain Abnormalities in Cocaine Addiction. Dang J, Tao Q, Niu X, Zhang M, Gao X, Yang Z, Yu M, Wang W, Han S, Cheng J, Zhang Y. Front Psychiatry. 2022 Jun 24;13:927075. doi: 10.3389/fpsyt.202...

Patterns of pregabalin prescribing in four German federal states: analysis of routine data to investigate potential misuse of pregabalin.

09. August 2022 | Gabapentinoide

Patterns of pregabalin prescribing in four German federal states: analysis of routine data to investigate potential misuse of pregabalin. Flemming R. BMJ Open. 2022 Jul 25;12(7):e060104. doi: 10.1136/bmjopen-2021-060104. PMID: 358790...

Warnhinweis zur Verordnung von Pregabalin

09. August 2022 | Gabapentinoide

Warnhinweis zur Verordnung von Pregabalin Anlässlich des zunehmenden missbräuchlichen Einsatzes des Medikaments Pregabalin weist die Qualitätssicherungskommission „Substitution“ bei der KV Bremen auf einige Gesichtspunkte bei der Verordnung von P...

Notes from the Field: Trends in Gabapentin Detection and Involvement in Drug Overdose Deaths — 23 States and the District of Columbia, 2019–2020.

09. August 2022 | Gabapentinoide

Notes from the Field: Trends in Gabapentin Detection and Involvement in Drug Overdose Deaths — 23 States and the District of Columbia, 2019–2020. Mattson CL, Chowdhury F, Gilson TP. MMWR Morb Mortal Wkly Rep 2022;71:664–666. doi...

Addiction Classic: The 1964 US Surgeon General's report on smoking and health.

02. August 2022 | Nikotin

Addiction Classic: The 1964 US Surgeon General's report on smoking and health. Hall, W. (2022), Addiction. doi.org/10.1111/add.16007 https://onlinelibrary.wiley.com/doi/full/10.1111

Exploring e-psychonauts perspectives towards cocaine effects and toxicity.

02. August 2022 | Kokain

Exploring e-psychonauts perspectives towards cocaine effects and toxicity. Assi S, Keenan A, Al Hamid A. Subst Abuse Treat Prev Policy. 2022 Jun 27;17(1):48. doi: 10.1186/s13011-022-00455-5. PMID: 35761409; PMCID: PMC9238119. https:...

Association of cannabis potency with mental ill health and addiction: a systematic review

02. August 2022 | Cannabis als Rauschmittel

Association of cannabis potency with mental ill health and addiction: a systematic review Petrilli, Kat et al. The Lancet Psychiatry, Volume 0, Issue 0 https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(22)00161-4/fulltext

REM Sleep Engages MCH Neurons to Reduce Cocaine Seeking

02. August 2022 | Kokain

REM Sleep Engages MCH Neurons to Reduce Cocaine Seeking Guo, Rong et al. Biological Psychiatry, Volume 0, Issue 0 https://www.biologicalpsychiatryjournal.com/article/S0006-3223(22)01321-X/fulltext

Pharmacological treatment for methamphetamine withdrawal: A systematic review and meta-analysis of randomised controlled trials.

02. August 2022 | Amphetamine

Pharmacological treatment for methamphetamine withdrawal: A systematic review and meta-analysis of randomised controlled trials. Acheson, LS, Williams, BH, Farrell, M, McKetin, R, Ezard, N, Siefried, KJ. Drug...

When someone overdoses on fentanyl and makes it to the hospital Emergency Department, a high dose of buprenorphine is a lifesaver.

02. August 2022 | Fentanyl

When someone overdoses on fentanyl and makes it to the hospital Emergency Department, a high dose of buprenorphine is a lifesaver. Dr. Gail D’Onofrio, an expert in emergency medicine and addiction, knows that to be true. “In emergency medicine, I...

Adapting methadone inductions to the fentanyl era

02. August 2022 | Fentanyl

Adapting methadone inductions to the fentanyl era Buresh, Megan et al. Journal of Substance Abuse Treatment, Volume 141, 108832 Abstract https://www.journalofsubstanceabusetreatment.com/article/S0740-5472(22)00114-3/fulltext

"It wasn't here, and now it is. It's everywhere": fentanyl's rising presence in Oregon's drug supply.

02. August 2022 | Fentanyl

"It wasn't here, and now it is. It's everywhere": fentanyl's rising presence in Oregon's drug supply. Shin SS, LaForge K, Stack E, Pope J, Leichtling G, Larsen JE, Leahy JM, Seaman A, Hoover D, Chisholm L, Blazes C, Baker R, Byers M, Branso...

USA. The NIDA-funded National Drug Early Warning System (NDEWS), Coordinating Center at UF

28. Juli 2022 | Verschiedene

USA. The NIDA-funded National Drug Early Warning System (NDEWS), Coordinating Center at UF The National Drug Early Warning System (NDEWS), funded to the University of Florida by the National Institute on Drug Abuse (NIDA), provides the fiel...

The CannTeen Study: Cannabis use disorder, depression, anxiety, and psychotic-like symptoms in adolescent and adult cannabis users and age-matched controls.

28. Juli 2022 | Cannabis als Rauschmittel

The CannTeen Study: Cannabis use disorder, depression, anxiety, and psychotic-like symptoms in adolescent and adult cannabis users and age-matched controls. Lawn W, Mokrysz C, Lees R, Trinci K, Petrilli K, Skumlien M, Borissova A, Ofori S, ...

Building a Better Painkiller

28. Juli 2022 | Cannabis als Medizin

Building a Better Painkiller On a quest to develop more effective pain medicines, scientists are studying how CBD inhibits pain-sensing neurons. (Harvard Medical School, USA, 15.07.2022) https://hms.harvard.edu/news/building-better-painkiller

Online surveillance of novel psychoactive substances (NPS): Monitoring Reddit discussions as a predictor of increased NPS-related exposures.

28. Juli 2022 | Neue Psychoaktive Substanzen

Online surveillance of novel psychoactive substances (NPS): Monitoring Reddit discussions as a predictor of increased NPS-related exposures. Barenholtz E, Krotulski AJ, Morris P, Fitzgerald ND, Le A, Papsun DM, Logan BK, Hahn WE, Goldberger...

EMCDDA. Infographic: benzodiazepines notifications to the Early Warning System and seizures

28. Juli 2022 | Benzodiazepine

EMCDDA. Infographic: benzodiazepines notifications to the Early Warning System and seizures This infographic coming from the publication New psychoactive substances: 25 years of early warning and response in Europe — an update from the...

Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020

28. Juli 2022 | Alkohol

Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020 Bryazka, Dana et al. The Lancet, Volume 400, Issue 10347, 185 - 235 https://www.thel...

Begleiterhebung zu medizinischem Cannabis: Bedingt aussagekräftig

28. Juli 2022 | Cannabis als Medizin

Begleiterhebung zu medizinischem Cannabis: Bedingt aussagekräftig Dtsch Arztebl 2022; 119(29-30): A-1290 / B-1082 Kurz, Charlotte; Lau, Tobias https://www.aerzteblatt.de/archiv/226212/Begleiterhebung-zu-medizinischem-Cannabis-Bedingt-aussagekra...

High-strength cannabis linked to addiction and mental health problems

28. Juli 2022 | Cannabis als Rauschmittel

High-strength cannabis linked to addiction and mental health problems Largest ever study into the health effects of different types of cannabis highlights concerns about stronger forms of the drug. (University of Bath, 25.07.2022) https://www.ba...

WCM. Wissenschaftsnetzwerk Cannabinoide in der Medizin

14. Juli 2022 | Cannabis als Medizin

WCM. Wissenschaftsnetzwerk Cannabinoide in der Medizin Das WCM ermöglicht einen transdisziplinären und interprofessionellen Austausch, um den wissenschaftlichen Erkenntnisgewinn zu Cannabinoiden in der Medizin zu fördern. Das Wissensch...

Cannabis-Based Products for Chronic Pain: A Systematic Review.

14. Juli 2022 | Cannabis als Medizin

Cannabis-Based Products for Chronic Pain: A Systematic Review. Marian S. McDonagh, Benjamin J. Morasco, Jesse Wagner, et al; Ann Intern Med. [Epub 7 June 2022]. doi:10.7326/M21-4520 https://www.acpjournals.org/doi/10.7326/M21-4520

The practice and embodiment of "goofballs": A qualitative study exploring the co-injection of methamphetamines and opioids.

14. Juli 2022 | Amphetamine

The practice and embodiment of "goofballs": A qualitative study exploring the co-injection of methamphetamines and opioids. Ivsins A, Fleming T, Barker A, Mansoor M, Thakarar K, Sue K, McNeil R. Int J Drug Policy. 2022 Jul 10;107:103...

USA. Q2 2022 Trend Reports: NPS Benzodiazepines, NPS Opioids, NPS Stimulants & Hallucinogens, and Synthetic Cannabinoids

14. Juli 2022 | Neue Psychoaktive Substanzen

USA. Q2 2022 Trend Reports: NPS Benzodiazepines, NPS Opioids, NPS Stimulants & Hallucinogens, and Synthetic Cannabinoids About: With funding from the National Institute of Justice (NIJ), the Center for Forensic Science Research and Education ...

Xylazine (CCENDU Drug Alert)

14. Juli 2022 | Verschiedene

Xylazine (CCENDU Drug Alert) Canadian Centre on Substance Use and Addiction, 2022 Summarizes the increased risk of accidental overdose due to xylazine in Canada’s unregulated drug supply. Xylazine is a non-opioid pain reliever developed as...

Abuse of tropicamide eye drops: review of clinical data.

12. Juli 2022 | Verschiedene

Abuse of tropicamide eye drops: review of clinical data. Bellman V, Ukolova A, Erovichenkova E, Lam S, Srivastava HK, Bruce J, Burgess DM. Braz J Psychiatry. 2022 Jun 21. doi: 10.47626/1516-4446-2021-2446. Epub ahead of print. PMID: ...

Stigmatization of Benzodiazepines: Pharmacologic and Nonpharmacologic Contributions.

11. Juli 2022 | Benzodiazepine

Stigmatization of Benzodiazepines: Pharmacologic and Nonpharmacologic Contributions. Silberman EK. Psychother Psychosom. 2022 Jun 9:1-3. doi: 10.1159/000525208. Epub ahead of print. PMID: 35679832. https://www.karger.com/Articl...

Over One Hundred Years of MDMA Research

11. Juli 2022 | Amphetamine

Over One Hundred Years of MDMA Research 3,4-Methylenedioxymethamphetamine (MDMA), also known as Mandy, Molly, Ecstasy or ‘E’, is a class A drug known for inducing feelings of happiness, chattiness, liveliness, and overall feelings of ecstasy, mak...

Characterizing the Experience of Tapentadol Nonmedical Use: Mixed Methods Study.

11. Juli 2022 | Opioide

Characterizing the Experience of Tapentadol Nonmedical Use: Mixed Methods Study. Vosburg SK, Dailey-Govoni T, Beaumont J, Butler SF, Green JL. JMIR Form Res. 2022 Jun 10;6(6):e16996. doi: 10.2196/16996. PMID: 35687397; PMCID: PM...

Novel Synthetic Opioids (NSO) Use in Opioid Dependents Entering Detoxification Treatment.

11. Juli 2022 | Opioide

Novel Synthetic Opioids (NSO) Use in Opioid Dependents Entering Detoxification Treatment. Specka M, Kuhlmann T, Bonnet U, Sawazki J, Schaaf L, Kühnhold S, Steinert R, Grigoleit T, Eich H, Zeiske B, Niedersteberg A, Steiner K, Schifano F, Sc...

Schweiz. Cannabis für medizinische Zwecke in der Schweiz künftig erlaubt

11. Juli 2022 | Cannabis als Medizin

Schweiz. Cannabis für medizinische Zwecke in der Schweiz künftig erlaubt Genf – In der Schweiz ist der Konsum von Cannabis zu medizinischen Zwecken künftig erlaubt. Die Regierung in Bern beschloss heute, das Verbot des medizinischen Cannabiskonsu...

Abschlussbericht der Begleiterhebung nach § 31 Absatz 6 des Fünften Buches Sozialgesetzbuch zur Verschreibung und Anwendung von Cannabisarzneimitteln

11. Juli 2022 | Cannabis als Medizin

Abschlussbericht der Begleiterhebung nach § 31 Absatz 6 des Fünften Buches Sozialgesetzbuch zur Verschreibung und Anwendung von Cannabisarzneimitteln BfArM, 06.07.2022 https://www.bfarm.de/SharedDocs/Downloads/DE/Bundesopiumstelle/Cannabis/Absch...

Begleiterhebung: Cannabis wird vor allem gegen chronische Schmerzen eingesetzt

11. Juli 2022 | Cannabis als Medizin

Begleiterhebung: Cannabis wird vor allem gegen chronische Schmerzen eingesetzt Bonn – Cannabis als Medizin wird vorrangig gegen chronische Schmerzen (76,4 Prozent) eingesetzt. Weitere häufig behandelte Symptome sind Spastik (9,6 Prozent) beziehun...

Impact of fentanyl use on initiation and discontinuation of methadone and buprenorphine/naloxone among people with prescription-type opioid use disorder: secondary analysis of a Canadian treatment trial.

11. Juli 2022 | Fentanyl

Impact of fentanyl use on initiation and discontinuation of methadone and buprenorphine/naloxone among people with prescription-type opioid use disorder: secondary analysis of a Canadian treatment trial. Socias ME, Wood E, Le Foll B, Lim R,...

Dose- and Sex-Dependent Bidirectional Relationship between Intravenous Fentanyl Self-Administration and Gut Microbiota.

11. Juli 2022 | Fentanyl

Dose- and Sex-Dependent Bidirectional Relationship between Intravenous Fentanyl Self-Administration and Gut Microbiota. Ren M, Lotfipour S. Microorganisms. 2022 May 30;10(6):1127. doi: 10.3390/microorganisms10061127. PMID: 35744645; ...

Fentanyl preference among people who use opioids in New York City.

11. Juli 2022 | Fentanyl

Fentanyl preference among people who use opioids in New York City. Urmanche AA, Beharie N, Harocopos A. Drug Alcohol Depend. 2022 Jun 6;237:109519. doi: 10.1016/j.drugalcdep.2022.109519. Epub ahead of print. PMID: 35714532. Abstract...

The Problematic Use of Tramadol Is Increasing in France

27. Juni 2022 | Opioide

The Problematic Use of Tramadol Is Increasing in France Caroline Guignot Medscape - Apr 18, 2022. https://www.medscape.com/viewarticle/972311

The iCannTookit: a consensus-based, flexible framework for measuring contemporary cannabis use.

27. Juni 2022 | Cannabis als Rauschmittel

The iCannTookit: a consensus-based, flexible framework for measuring contemporary cannabis use. Lorenzetti, V., Hindocha, C., Petrilli, K., Griffiths, P., Brown, J., Castillo-Carniglia, Á., Caulkins, J.P., Englund, A., El Sohly, M.A., Gage,...

Controlling for pleasure and risk: The experiences of sexuality and gender diverse people who use GHB.

26. Juni 2022 | Verschiedene

Controlling for pleasure and risk: The experiences of sexuality and gender diverse people who use GHB. Freestone J, Prestage G, Bourne A, Ezard N, Race K, Nedanoski A, Murray J, Siefried KJ. Int J Drug Policy. 2022 Jul;105:103747. do...

USA. Challenges in Identifying Novel Psychoactive Substances and a Stronger Path Forward

22. Juni 2022 | Opioide

USA. Challenges in Identifying Novel Psychoactive Substances and a Stronger Path Forward The importance of non-targeted testing to keep pace with a rapidly evolving synthetic opioid market. (NIJ – National Institute of Justice, USA, 11.06.2022) ...

Alcohol Consumption Levels and Health Care Utilization in Germany - Results from the GEDA 2014/2015-EHIS Study

21. Juni 2022 | Alkohol

Alcohol Consumption Levels and Health Care Utilization in Germany - Results from the GEDA 2014/2015-EHIS Study Sinclair Carr, Christina Lindemann, Ludwig Kraus, Jürgen Rehm, Bernd Schulte und Jakob Manthey Online veröffentlicht:June 14...

Gabapentinoids: repeating mistakes of the past?.

21. Juni 2022 | Gabapentinoide

Gabapentinoids: repeating mistakes of the past?. Murnion, B., Schaffer, A., Cairns, R. and Brett, J. (2022), Addiction. doi.org/10.1111/add.15970 https://onlinelibrary.wiley.com/doi/full/10.1111/add.15970

USA. Bromazolam Prevalence Surging Across the United States Driven In Part by Increasing Detections Alongside Fentanyl

21. Juni 2022 | Benzodiazepine

USA. Bromazolam Prevalence Surging Across the United States Driven In Part by Increasing Detections Alongside Fentanyl Purpose: The objective of this announcement is to notify public health and safety, law enforcement, first responders, clinician...

USA. Bromazolam Prevalence Surging Across the United States Driven In Part by Increasing Detections Alongside Fentanyl

21. Juni 2022 | Fentanyl

EMCDDA. New psychoactive substances: 25 years of early warning and response in Europe — an update from the EU Early Warning System

21. Juni 2022 | Neue Psychoaktive Substanzen

EMCDDA. New psychoactive substances: 25 years of early warning and response in Europe — an update from the EU Early Warning System This update from the EU Early Warning System overviews the NPS situation in Europe in 2020-2021 and highlights emer...

Entwicklung der Zahl der 2000 bis 2020 in den Krankenhäusern wegen einer akuten Alkoholintoxikation vollstationär behandelten Patientinnen mit Wohnsitz in Deutschland je 100.000 Einwohnerinnen – Ein Kurzüberblick

21. Juni 2022 | Alkohol

Entwicklung der Zahl der 2000 bis 2020 in den Krankenhäusern wegen einer akuten Alkoholintoxikation vollstationär behandelten Patient*innen mit Wohnsitz in Deutschland je 100.000 Einwohner*innen – Ein Kurzüberblick Theo Baumgärtner Sucht Hamburg...

P300 Event-Related Potentials as a Marker of Craving in Opioid Use Disorder: a Systematic Literature Review

06. Juni 2022 | Opioide

P300 Event-Related Potentials as a Marker of Craving in Opioid Use Disorder: a Systematic Literature Review Skrenes A., Labonté L.E., Muñoz-Violant S., Khehra J., Krigolson O., and Schütz C HEROIN ADDICTION AND RELATED CLINICAL PROBLEMS - ...

Opioidreport 2022 (begleitender Foliensatz)

06. Juni 2022 | Opioide

Opioidreport 2022 (begleitender Foliensatz) Gerd Glaeske unter Mitarbeit von Andrea Ernst, Friederike Höfel, Elisabeth Horn, Mona Lorenz, Julia Misonow, Lutz Muth, Anna Nymbach-Dietrich, Jonas Poskowsky März 2022, Universität Bre...

Opioidreport 2022

06. Juni 2022 | Opioide

Opioidreport 2022 Gerd Glaeske unter Mitarbeit von Andrea Ernst, Friederike Höfel, Elisabeth Horn, Mona Lorenz, Julia Misonow, Lutz Muth, Anna Nymbach-Dietrich, Jonas Poskowsky März 2022, Universität Bremen, SOCIUM, Mary-So...

Zu früh, zu oft: Werden Opioide von Ärzten unterschätzt? Studie unter Leitung des Arzneimittelexperten Prof. Dr. Gerd Glaeske

06. Juni 2022 | Opioide

Zu früh, zu oft: Werden Opioide von Ärzten unterschätzt? Studie unter Leitung des Arzneimittelexperten Prof. Dr. Gerd Glaeske Forscherteam der Universität Bremen ermittelt steigende Vergabe bei zweifelhaften Indikationen - trotz hoher Suchtg...

Ketamin: Antidepressiver Wirkmechanismus entdeckt

06. Juni 2022 | Verschiedene

Ketamin: Antidepressiver Wirkmechanismus entdeckt München – Der antidepressive Effekt von Ketamin könnte durch die Hochregulation bestimmter Kaliumkanäle im Hippocampus entstehen – den sogenannten KCNQ2. Zu diesem Ergebnis kam ein Forschungsteam ...

Kamini, a little recognised source of illicit opioid: A case series of 12 patients.

05. Juni 2022 | Opioide

Kamini, a little recognised source of illicit opioid: A case series of 12 patients. Khan T, Ariyawansa P, Quinn J, Hayllar J. Drug Alcohol Rev. 2022 May 12. doi: 10.1111/dar.13475. Epub ahead of print. PMID: 35555819. Abstract http...

Representation of Benzodiazepines in Treatment Guidelines: The Paradox of Undesirable Objectivit

05. Juni 2022 | Benzodiazepine

Representation of Benzodiazepines in Treatment Guidelines: The Paradox of Undesirable Objectivity. Starcevic V. Psychother Psychosom. 2022 May 12:1-5. doi: 10.1159/000524772. Epub ahead of print. PMID: 35551128. https://www.karger.c...

Toxicological Relevance of Pregabalin in Heroin Users: A Two-Year Postmortem Population Study.

05. Juni 2022 | Gabapentinoide

Toxicological Relevance of Pregabalin in Heroin Users: A Two-Year Postmortem Population Study. Nahar LK, Murphy K, Paterson S. J Anal Toxicol. 2022 May 20;46(5):471-478. doi: 10.1093/jat/bkab070. PMID: 34114622; PMCID: PMC9122506. h...

Notes from the Field: Trends in Gabapentin Detection and Involvement in Drug Overdose Deaths - 23 States and the District of Columbia, 2019-2020.

05. Juni 2022 | Gabapentinoide

Notes from the Field: Trends in Gabapentin Detection and Involvement in Drug Overdose Deaths - 23 States and the District of Columbia, 2019-2020. Mattson CL, Chowdhury F, Gilson TP. MMWR Morb Mortal Wkly Rep. 2022 May 13;71(19):664-6...

Sex differences in methamphetamine use disorder perused from pre-clinical and clinical studies: Potential therapeutic impacts.

05. Juni 2022 | Amphetamine

Sex differences in methamphetamine use disorder perused from pre-clinical and clinical studies: Potential therapeutic impacts. Daiwile AP, Jayanthi S, Cadet JL. Neurosci Biobehav Rev. 2022 Jun;137:104674. doi: 10.1016/j.neubiorev.202...

Trends in Methamphetamine Use in the Mainland of China, 2006-2015.

05. Juni 2022 | Amphetamine

Trends in Methamphetamine Use in the Mainland of China, 2006-2015. Zhang B, Yan X, Li Y, Zhu H, Lu Z, Jia Z. Front Public Health. 2022 Apr 28;10:852837. doi: 10.3389/fpubh.2022.852837. PMID: 35570894; PMCID: PMC9096246. https://www.ncbi.nlm.nih...

Identifying behaviours for survival and wellness among people who use methamphetamine with opioids in British Columbia: a qualitative study.

05. Juni 2022 | Amphetamine

Identifying behaviours for survival and wellness among people who use methamphetamine with opioids in British Columbia: a qualitative study. Corser J, Palis H, Fleury M, Lamb J, Lock K, McDougall J, Mehta A, Newman C, Spence H, Buxton JA.&n...

How dangerous is MDMA?

05. Juni 2022 | Amphetamine

How dangerous is MDMA? Frost J. Tidsskr Nor Laegeforen. 2022 May 19;142(8). English, Norwegian. doi: 10.4045/tidsskr.22.0309. PMID: 35635415. https://tidsskriftet.no/en/2022/05/editorial/how-dangerous-mdma

Drugs of abuse in tap water from eight European countries: Determination by use of supramolecular solvents and tentative evaluation of risks to human health.

05. Juni 2022 | Verschiedene

Drugs of abuse in tap water from eight European countries: Determination by use of supramolecular solvents and tentative evaluation of risks to human health. Muñiz-Bustamante L, Caballero-Casero N, Rubio S. Environ Int. 2022 Jun;164:...

Health Effects Associated With Kratom (Mitragyna speciosa) and Polysubstance Use: A Narrative Review.

05. Juni 2022 | Verschiedene

Health Effects Associated With Kratom (Mitragyna speciosa) and Polysubstance Use: A Narrative Review. Striley CW, Hoeflich CC, Viegas AT, Berkowitz LA, Matthews EG, Akin LP, Iheanyi-Okeahialam C, Mansoor U, McCurdy CR. Subst Abuse. 2...

A Focus on Abuse/Misuse and Withdrawal Issues with Selective Serotonin Reuptake Inhibitors (SSRIs): Analysis of Both the European EMA and the US FAERS Pharmacovigilance Databases.

05. Juni 2022 | Verschiedene

A Focus on Abuse/Misuse and Withdrawal Issues with Selective Serotonin Reuptake Inhibitors (SSRIs): Analysis of Both the European EMA and the US FAERS Pharmacovigilance Databases. Chiappini S, Vickers-Smith R, Guirguis A, Corkery JM, Martin...

Trace residue identification, characterization, and longitudinal monitoring of the novel synthetic opioid β-U10, from discarded drug paraphernalia.

05. Juni 2022 | Opioide

Trace residue identification, characterization, and longitudinal monitoring of the novel synthetic opioid β-U10, from discarded drug paraphernalia. West H, Fitzgerald JL, Hopkins KL, Leeming MG, DiRago M, Gerostamoulos D, Clark N, Diet...

Role of Mitochondrial Dynamics in Cocaine's Neurotoxicity.

05. Juni 2022 | Kokain

Role of Mitochondrial Dynamics in Cocaine's Neurotoxicity. Wen S, Aki T, Funakoshi T, Unuma K, Uemura K. Int J Mol Sci. 2022 May 12;23(10):5418. doi: 10.3390/ijms23105418. PMID: 35628228; PMCID: PMC9145816. https://www.ncbi.nlm.nih....

Signals of increasing co-use of stimulants and opioids from online drug forum data.

04. Juni 2022 | Amphetamine

Signals of increasing co-use of stimulants and opioids from online drug forum data. Sarker A, Al-Garadi MA, Ge Y, Nataraj N, Jones CM, Sumner SA. Harm Reduct J. 2022 May 25;19(1):51. doi: 10.1186/s12954-022-00628-2. PMID: 35614501; P...

New Psychoactive Substances Consumption in Opioid-Use Disorder Patients.

04. Juni 2022 | Neue Psychoaktive Substanzen

New Psychoactive Substances Consumption in Opioid-Use Disorder Patients. Alías-Ferri M, Pellegrini M, Marchei E, Pacifici R, Rotolo MC, Pichini S, Pérez-Mañá C, Papaseit E, Muga R, Fonseca F, Torrens M, Farré M. Biology (Basel). 2022...

UNODC. Synthetic Drugs in East and Southeast Asia Latest developments and challenges - 2022

04. Juni 2022 | Amphetamine

UNODC. Synthetic Drugs in East and Southeast Asia Latest developments and challenges - 2022 United Nations Office on Drugs and Crime (UNODC), Global SMART Programme, 2022 https://www.unodc.org/roseap/uploads/documents/Publications/2022/Synt...

Non-fentanyl-derived synthetic opioids emerging during recent years.

04. Juni 2022 | Opioide

Non-fentanyl-derived synthetic opioids emerging during recent years. Hasegawa K, Minakata K, Suzuki M, Suzuki O. Forensic Toxicol. 2022 Apr 29:1-10. doi: 10.1007/s11419-022-00624-y. Epub ahead of print. PMID: 35528111; PMCID: PMC9052...

Unique Pharmacology, Brain Dysfunction, and Therapeutic Advancements for Fentanyl Misuse and Abuse.

04. Juni 2022 | Fentanyl

Unique Pharmacology, Brain Dysfunction, and Therapeutic Advancements for Fentanyl Misuse and Abuse. Han Y, Cao L, Yuan K, Shi J, Yan W, Lu L. Neurosci Bull. 2022 May 15:1–18. doi: 10.1007/s12264-022-00872-3. Epub ahead of print. PMID...

"They say it's fentanyl, but they honestly look like Perc 30s": Initiation and use of counterfeit fentanyl pills.

04. Juni 2022 | Fentanyl

"They say it's fentanyl, but they honestly look like Perc 30s": Initiation and use of counterfeit fentanyl pills. Daniulaityte R, Sweeney K, Ki S, Doebbeling BN, Mendoza N. Harm Reduct J. 2022 May 25;19(1):52. doi: 10.1186/s12954-022...

A comprehensive evaluation of the potential binding poses of fentanyl and its analogs at the µ-opioid receptor.

04. Juni 2022 | Fentanyl

A comprehensive evaluation of the potential binding poses of fentanyl and its analogs at the µ-opioid receptor. Xie B, Goldberg A, Shi L. Comput Struct Biotechnol J. 2022 May 14;20:2309-2321. doi: 10.1016/j.csbj.2022.05.013. PMID: 35...

UK/Frankreich. First the UK, now France: is needle-spiking spreading in European clubs?

26. Mai 2022 | Verschiedene

UK/Frankreich. First the UK, now France: is needle-spiking spreading in European clubs? Fear of needle-spiking is growing among clubbers in France, a few months after a wave of similar anxiety swept the UK. There have been more than 100 re...

Niederlande. First report of needle spiking now also in the Netherlands

26. Mai 2022 | Verschiedene

Niederlande. First report of needle spiking now also in the Netherlands Since last winter, there are reports of women being drugged on nights out in the UK, France and Belgium. Now, the first case has also surfaced in the Netherlands. (DutchRevie...

Kanada. CCENDU Drug Alert - Nitazenes

26. Mai 2022 | Opioide

Kanada. CCENDU Drug Alert - Nitazenes What Are Nitazenes? Nitazenes are potent synthetic opioids from a drug class known as benzimidazole-opioids. Some nitazenes are estimated to be several times more potent than fentanyl. They were devel...

First Ever Clinical Trial with Ibogaine for Opioid Dependency

26. Mai 2022 | Verschiedene

First Ever Clinical Trial with Ibogaine for Opioid Dependency It’s been fifty years since the anti-addictive properties of ibogaine were discovered and finally the dream of those helping people with substance use disorder is coming true – clinica...

Rapid changes in illegally manufactured fentanyl products and prices in the United States

26. Mai 2022 | Fentanyl

Rapid changes in illegally manufactured fentanyl products and prices in the United States Kilmer, B., Pardo, B., Pujol, T. A., and Caulkins, J. P. (2022) Addiction. doi.org/10.1111/add.15942 https://onlinelibrary.wiley...

What is fentanyl?

26. Mai 2022 | Fentanyl

What is fentanyl? Pharmaceutical fentanyl is a synthetic opioid, approved for treating severe pain, typically advanced cancer pain.1 It is 50 to 100 times more potent than morphine. It is prescribed in the form of transdermal patches or loze...

How a powdered fentanyl program has improved a client’s quality of life

26. Mai 2022 | Fentanyl

How a powdered fentanyl program has improved a client’s quality of life Andreas Laupacis CMAJ May 16, 2022 194 (19) E681; doi.org/10.1503/cmaj.220649 https://www.cmaj.ca/content/194/19/E681

USA. PODCAST: Director of NIDA Dr. Nora Volkow

26. Mai 2022 | Fentanyl

USA. PODCAST: Director of NIDA Dr. Nora Volkow Like many families, Dr. Nora Volkow’s had kept it a secret that her grandfather had a substance use disorder and eventually committed suicide. Today, as the director of the National Institute on Drug...

USA/China. US asks China to do more to stop rising drug deaths from fentanyl

26. Mai 2022 | Fentanyl

USA/China. US asks China to do more to stop rising drug deaths from fentanyl Beijing must "do more" to stop the export of chemicals to make fentanyl, the US drug law enforcement agency has said. The plea from the Drug Enforcement Agency (DEA) co...

Case report: acute care management of severe opioid withdrawal with IV fentanyl.

08. Mai 2022 | Fentanyl

Case report: acute care management of severe opioid withdrawal with IV fentanyl. Azar P, Westenberg JN, Ignaszewski MJ, Wong JSH, Isac G, Mathew N, Krausz RM. Addict Sci Clin Pract. 2022 Apr 5;17(1):22. doi: 10.1186/s13722-022-00305-...

Patterns of and Rationale for the Co-use of Methamphetamine and Opioids: Findings From Qualitative Interviews in New Mexico and Nevada.

08. Mai 2022 | Amphetamine

Patterns of and Rationale for the Co-use of Methamphetamine and Opioids: Findings From Qualitative Interviews in New Mexico and Nevada. Rhed BD, Harding RW, Marks C, Wagner KT, Fiuty P, Page K, Wagner KD. Front Psychiatry. 2022 Mar 2...

Pregabalin (Lyrica): findings of safety study on risks during pregnancy

08. Mai 2022 | Gabapentinoide

Pregabalin (Lyrica): findings of safety study on risks during pregnancy A new study has suggested pregabalin may slightly increase the risk of major congenital malformations if used in pregnancy. Patients should continue to use effective co...

Fatalities associated with gabapentinoids in England (2004-2020).

08. Mai 2022 | Gabapentinoide

Fatalities associated with gabapentinoids in England (2004-2020). Kalk NJ, Chiu CT, Sadoughi R, Baho H, Williams BD, Taylor D, Copeland CS. Br J Clin Pharmacol. 2022 Apr 18. doi: 10.1111/bcp.15352. Epub ahead of print. PMID: 35435281...

An algorithm to identify gabapentin misuse and/or abuse in administrative claims data.

08. Mai 2022 | Gabapentinoide

An algorithm to identify gabapentin misuse and/or abuse in administrative claims data. Zhao D, Nunes AP, Baek J, Lapane KL. Drug Alcohol Depend. 2022 Mar 26;235:109429. doi: 10.1016/j.drugalcdep.2022.109429. Epub ahead of print. PMID...

Phenobarbital use in benzodiazepine and z-drug detoxification: a single-centre 15-year observational retrospective study in clinical practice.

08. Mai 2022 | Benzodiazepine

Phenobarbital use in benzodiazepine and z-drug detoxification: a single-centre 15-year observational retrospective study in clinical practice. Sartori S, Crescioli G, Brilli V, Traversoni S, Lanzi C, Vannacci A, Mannaioni G, Lombardi N.&nbs...

Eine ambulante Entzugsbehandlung von Kratom bei sozialer Phobie: psychotherapeutische Praxis trifft suchtpsychiatrische Institutsambulanz [An Outpatient Withdrawal Treatment of Kratom in Social Phobia: Psychotherapeutic Surgery Meets Addiction Psychiatric

08. Mai 2022 | Verschiedene

Eine ambulante Entzugsbehandlung von Kratom bei sozialer Phobie: psychotherapeutische Praxis trifft suchtpsychiatrische Institutsambulanz [An Outpatient Withdrawal Treatment of Kratom in Social Phobia: Psychotherapeutic Surgery Meets Addiction Psy...

Addiction of High Dose of Benzodiazepine: Verona Detox Approach With Flumazenil.

08. Mai 2022 | Benzodiazepine

Addiction of High Dose of Benzodiazepine: Verona Detox Approach With Flumazenil. Casari R, Metastasio A, Zamboni L, Biasioli M, Campagnari S, Lugoboni F. Front Psychiatry. 2022 Mar 31;13:857376. doi: 10.3389/fpsyt.2022.857376. PMID: 354320...

A descriptive analysis of concomitant opioid and benzodiazepine medication use and associated adverse drug events in United States adults between 2009 and 2018.

08. Mai 2022 | Benzodiazepine

A descriptive analysis of concomitant opioid and benzodiazepine medication use and associated adverse drug events in United States adults between 2009 and 2018. Marwitz KK, Noureldin M. Explor Res Clin Soc Pharm. 2022 Mar 20;5:100130...

Experiences with benzodiazepine use, tapering, and discontinuation: an Internet survey.

08. Mai 2022 | Benzodiazepine

Experiences with benzodiazepine use, tapering, and discontinuation: an Internet survey. Reid Finlayson AJ, Macoubrie J, Huff C, Foster DE, Martin PR. Ther Adv Psychopharmacol. 2022 Apr 25;12:20451253221082386. doi: 10.1177/2045125322...

New Synthetic Opioids Use among Patients in Treatment for an Opioid Use Disorder in Barcelona.

08. Mai 2022 | Opioide

New Synthetic Opioids Use among Patients in Treatment for an Opioid Use Disorder in Barcelona. Alías-Ferri M, Marchei E, Pacifici R, Pichini S, Pellegrini M, Pérez-Mañá C, Papaseit E, Muga R, Fonseca F, Farré M, Torrens M. Eur Addict...

New Synthetic Opioids Use among Patients in Treatment for an Opioid Use Disorder in Barcelona. (2)

08. Mai 2022 | Opioide

Unspecified opioids among opioid overdoses in Oslo, Norway.

08. Mai 2022 | Opioide

Unspecified opioids among opioid overdoses in Oslo, Norway. Iqbal ZZ, Nguyen TMT, Brekke M, Vallersnes OM. BMC Res Notes. 2022 Apr 9;15(1):134. doi: 10.1186/s13104-022-06022-2. PMID: 35397589; PMCID: PMC8994352. https://www.ncbi.nlm...

Naloxone’s dose-dependent displacement of [11C]carfentanil and duration of receptor occupancy in the rat brain.

08. Mai 2022 | Fentanyl

Naloxone’s dose-dependent displacement of [11C]carfentanil and duration of receptor occupancy in the rat brain. Kang, Y., O’Conor, K.A., Kelleher, A.C. et al. Sci Rep 12, 6429 (2022). doi.org/10.1038/s41598-022-09601-2 http...

Kurzbericht "Konsumgewohnheiten, soziale Hintergründe und Hilfebedarfe von Erwachsenen mit einem riskanten oder abhängigen Kokainkonsum (KOKOS)"

08. Mai 2022 | Kokain

Kurzbericht "Konsumgewohnheiten, soziale Hintergründe und Hilfebedarfe von Erwachsenen mit einem riskanten oder abhängigen Kokainkonsum (KOKOS)" Kokainsicherstellungen erreichen jedes Jahr neue Rekordhöhen. Bisher kommen Konsumierende in de...

Emergent Synthetic Stimulant Replacing Drug Sold as Ecstasy, Molly

08. Mai 2022 | Verschiedene

Emergent Synthetic Stimulant Replacing Drug Sold as Ecstasy, Molly In 2020 and 2021, the Schedule I drug eutylone—typically sold as ecstasy, Molly or MDMA—was the most commonly encountered synthetic stimulant in forensic casework. While regulated...

Treatment of overdose in the synthetic opioid era.

08. Mai 2022 | Fentanyl

Treatment of overdose in the synthetic opioid era. Skolnick P. Pharmacol Ther. 2022 May;233:108019. doi: 10.1016/j.pharmthera.2021.108019. Epub 2021 Oct 9. PMID: 34637841. https://www.sciencedirect.com/science/article/pii/S016372582...

Effektivität von E-Zigaretten bei der Tabakentwöhnung

08. Mai 2022 | Nikotin

Effektivität von E-Zigaretten bei der Tabakentwöhnung Ein Vergleich mit Nikotinersatztherapie und keiner Nutzung evidenzbasierter Unterstützung in der deutschen Bevölkerung The effectiveness of e-cigarettes for smoking cessation—a comparison wit...

Different phases of ATS use call for different interventions: a large qualitative study in Europe.

08. Mai 2022 | Amphetamine

Different phases of ATS use call for different interventions: a large qualitative study in Europe. Liebregts, N., Rigoni, R., Petruželka, B. et al. Harm Reduct J 19, 36 (2022). doi.org/10.1186/s12954-022-00617-5 https://har...

Knowing Your Limits with Cannabis: A Practical Guide to Assessing Your Cannabis Use

28. April 2022 | Cannabis als Rauschmittel

Knowing Your Limits with Cannabis: A Practical Guide to Assessing Your Cannabis Use Canadian Centre on Substance Use and Addiction, Kanada, 2022 Helps people reflect on their cannabis use patterns while providing tips and strategies to enc...

Opioid-sparing effect of cannabinoids for analgesia: an updated systematic review and meta-analysis of preclinical and clinical studies.

28. April 2022 | Cannabis als Medizin

Opioid-sparing effect of cannabinoids for analgesia: an updated systematic review and meta-analysis of preclinical and clinical studies. Nielsen, S., Picco, L., Murnion, B. et al. Neuropsychopharmacol. (2022). doi.org/10.1038/s41...

Cannabis for Medical Use: Versatile Plant Rather Than a Single Drug

28. April 2022 | Cannabis als Medizin

Cannabis for Medical Use: Versatile Plant Rather Than a Single Drug Shiri Procaccia, Gil Moshe Lewitus, Carni Lipson Feder, Anna Shapira, Paula Berman and David Meiri Front. Pharmacol., 25 April 2022, doi.org/10.3389/fphar.2022.894960 http...

An adaptive design to screen, treat, and retain people with opioid use disorders who use methamphetamine in methadone clinics (STAR-OM): study protocol of a clinical trial.

28. April 2022 | Amphetamine

An adaptive design to screen, treat, and retain people with opioid use disorders who use methamphetamine in methadone clinics (STAR-OM): study protocol of a clinical trial. Giang LM, Trang NT, Diep NB, Thuy DTD, Thuy DT, Hoe HD, Van HTH, Tr...

Cannabinoide reduzieren den Opioidverbrauch bei älteren Schmerzpatienten: Eine retrospektive Dreijahresauswertung einer ambulanten kassenärztlichen Praxis [Cannabinoids reduce opioid use in older patients with pain : Retrospective three-year analysis of d

23. April 2022 | Cannabis als Medizin

Cannabinoide reduzieren den Opioidverbrauch bei älteren Schmerzpatienten: Eine retrospektive Dreijahresauswertung einer ambulanten kassenärztlichen Praxis [Cannabinoids reduce opioid use in older patients with pain : Retrospective three-year analy...

Kanada. ‘I Want Them to Break Up with Their Drug Dealer’

23. April 2022 | Fentanyl

Kanada. ‘I Want Them to Break Up with Their Drug Dealer’ A new Vancouver program provides prescribed fentanyl with few barriers. (The Tyee, Kanada, 11.04.2022) https://thetyee.ca/News/2022/04/11/I-Want-Them-To-Break-Up-Drug-Dealer/

USA. ‘We’re done with dead kids’: U.S. bars are handing out free fentanyl tests

23. April 2022 | Fentanyl

USA. ‘We’re done with dead kids’: U.S. bars are handing out free fentanyl tests (…) Strips to test drugs for the presence of the deadly synthetic opioid are becoming more commonplace in bars, restaurants and venues as the country grapples with th...

Indien. 'Chitta' reaching Himachal via Punjab more lethal

22. April 2022 | Opioide

Indien. 'Chitta' reaching Himachal via Punjab more lethal Consuming ‘chitta’ regularly for three to four months could result in platelets falling below 10,000, which could prove fatal. (The Tribune, Indien, 15.04.2022) https://www.tribuneindia.c...

Associations between classic psychedelics and opioid use disorder in a nationally-representative U.S. adult sample.

11. April 2022 | Verschiedene

Associations between classic psychedelics and opioid use disorder in a nationally-representative U.S. adult sample. Jones, G., Ricard, J.A., Lipson, J. et al. Sci Rep 12, 4099 (2022). doi.org/10.1038/s41598-022-08085-4 http...

Medicinal Natural Products of Cannabis sativa Linn.: A Review.

09. April 2022 | Cannabis als Medizin

Medicinal Natural Products of Cannabis sativa Linn.: A Review. Odieka AE, Obuzor GU, Oyedeji OO, Gondwe M, Hosu YS, Oyedeji AO. The Molecules. 2022 Mar 4;27(5):1689. doi: 10.3390/molecules27051689. PMID: 35268790; PMCID: PM...

Routes of administration, reasons for use, and approved indications of medical cannabis in oncology: a scoping review.

09. April 2022 | Cannabis als Medizin

Routes of administration, reasons for use, and approved indications of medical cannabis in oncology: a scoping review. Vinette B, Côté J, El-Akhras A, Mrad H, Chicoine G, Bilodeau K. BMC Cancer. 2022 Mar 24;22(1):319. doi: 10.1186/s1...

The effects of MDMA-assisted therapy on alcohol and substance use in a phase 3 trial for treatment of severe PTSD.

09. April 2022 | Amphetamine

The effects of MDMA-assisted therapy on alcohol and substance use in a phase 3 trial for treatment of severe PTSD. Nicholas CR, Wang JB, Coker A, Mitchell JM, Klaire SS, Yazar-Klosinski B, Emerson A, Brown RT, Doblin R. Drug Alcohol ...

Updated cost-effectiveness of MDMA-assisted therapy for the treatment of posttraumatic stress disorder in the United States: Findings from a phase 3 trial.

09. April 2022 | Amphetamine

Updated cost-effectiveness of MDMA-assisted therapy for the treatment of posttraumatic stress disorder in the United States: Findings from a phase 3 trial. Marseille E, Mitchell JM, Kahn JG (2022) PLoS ONE 17(2): e0263252. doi.org/10...

Cocaethylene: When Cocaine and Alcohol Are Taken Together.

09. April 2022 | Kokain

Cocaethylene: When Cocaine and Alcohol Are Taken Together. Pergolizzi J, Breve F, Magnusson P, LeQuang JAK, Varrassi G. Cureus. 2022 Feb 22;14(2):e22498. doi: 10.7759/cureus.22498. PMID: 35345678; PMCID: PMC8956485. https://www.ncbi...

Cocaethylene: When Cocaine and Alcohol Are Taken Together.

09. April 2022 | Alkohol

Langfristiger Benzodiazepingebrauch könnte Synapsen angreifen

09. April 2022 | Benzodiazepine

Langfristiger Benzodiazepingebrauch könnte Synapsen angreifen München – Benzodiazepine könnten bei längerer Einnahme zum Verlust von Synapsen im Gehirn führen. Das berichtet eine Arbeitsgruppe um Jochen Herms und Mario Dorostkar vom Zentrum für N...

Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO).

09. April 2022 | Benzodiazepine

Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO). Shi Y, Cui M, Ochs K, Brendel M, Strübing FL, Briel N, Eckenweber F, Zou C, Banati...

Fachgesellschaft: E-Zigaretten zur Tabakentwöhnung ungeeignet

09. April 2022 | Nikotin

Fachgesellschaft: E-Zigaretten zur Tabakentwöhnung ungeeignet Berlin – Elektronische Zigaretten (E-Zigaretten) sind kein geeignetes Hilfsmittel dazu, mit dem Rauchen aufzuhören. Das erklärt die Deutsche Gesellschaft für Pneumologie und Beatmungsm...

Novel Psychoactive Substances: The Razor's Edge between Therapeutical Potential and Psychoactive Recreational Misuse.

05. April 2022 | Neue Psychoaktive Substanzen

Novel Psychoactive Substances: The Razor's Edge between Therapeutical Potential and Psychoactive Recreational Misuse. Correia B, Fernandes J, Botica MJ, Ferreira C, Quintas A. Medicines (Basel). 2022 Mar 1;9(3):19. doi: 10.3390/medic...

Current Situation of Methamphetamine Abuse and Related Research Progress.

05. April 2022 | Amphetamine

Current Situation of Methamphetamine Abuse and Related Research Progress. Hong SJ, Shen BY, Sun RJ, Yang GM, Duan CM, Nie QY, Zhang CB, Dong WJ, Yu H, Wang S, Liu PL, Wen PY, Li LH. Fa Yi Xue Za Zhi. 2021 Dec 25;37(6):763-775. Englis...

Nonmedical use of gabapentin and opioid agonist medications in treatment-seeking individuals with opioid use disorder.

05. April 2022 | Gabapentinoide

Nonmedical use of gabapentin and opioid agonist medications in treatment-seeking individuals with opioid use disorder. Ellis MS, Buttram ME, Kasper ZA. Drug Alcohol Depend. 2022 Mar 9;234:109400. doi: 10.1016/j.drugalcdep.2022.109400...

The Effects of Prenatal Exposure to Pregabalin on the Development of Ventral Midbrain Dopaminergic Neurons.

05. April 2022 | Gabapentinoide

The Effects of Prenatal Exposure to Pregabalin on the Development of Ventral Midbrain Dopaminergic Neurons. Alsanie WF, Alhomrani M, Gaber A, Habeeballah H, Alkhatabi HA, Felimban RI, Abdelrahman S, Hauser CAE, Chaudhary AG, Alamri AS, Raaf...

Pregabalin Abuse - A Case Report.

05. April 2022 | Gabapentinoide

Pregabalin Abuse - A Case Report. Svalina T, Kokalj Palandacic A. Psychiatr Danub. 2021 Spring-Summer;33(Suppl 4):1238-1239. PMID: 35354195. https://www.psychiatria-danubina.com/UserDocsImages/pdf/dnb_vol33_noSuppl%204/dnb_vol33_noS...

The Role of Gabapentinoids in the Substance Use Pattern of Adult Germans Seeking Inpatient Detoxification Treatment - A Pilot Study.

05. April 2022 | Gabapentinoide

The Role of Gabapentinoids in the Substance Use Pattern of Adult Germans Seeking Inpatient Detoxification Treatment - A Pilot Study. Bonnet U, Kanti AK, Scherbaum N, Specka M. J Psychoactive Drugs. 2022 Mar 15:1-10. doi: 10.1080/0279...

Pregabalin as adjunctive therapy in adult and pediatric patients with generalized tonic-clonic seizures: A randomized, placebo-controlled trial.

05. April 2022 | Gabapentinoide

Pregabalin as adjunctive therapy in adult and pediatric patients with generalized tonic-clonic seizures: A randomized, placebo-controlled trial. Driscoll J, Almas M, Gregorian G, Kyrychenko A, Makedonska I, Liu J, Patrick J, Scavone JM, Ant...

USA. Law enforcement seizures of pills containing fentanyl increased dramatically between 2018-2021

05. April 2022 | Fentanyl

USA. Law enforcement seizures of pills containing fentanyl increased dramatically between 2018-2021 NIH-supported research highlights growing, dangerous trend, particularly for people new to drug use. (NIH – National Institute on Drug Abuse...

Modelling buprenorphine reduction of fentanyl-induced respiratory depression.

05. April 2022 | Fentanyl

Modelling buprenorphine reduction of fentanyl-induced respiratory depression. Olofsen E, Algera MH, Moss L, Dobbins RL, Groeneveld GJ, van Velzen M, Niesters M, Dahan A, Laffont CM. JCI Insight. 2022 Mar 22:e156973. doi: 10.1172/jci....

In vitro and in vivo pharmaco-dynamic study of the novel fentanyl derivatives: Acrylfentanyl, Ocfentanyl and Furanylfentanyl.

05. April 2022 | Fentanyl

In vitro and in vivo pharmaco-dynamic study of the novel fentanyl derivatives: Acrylfentanyl, Ocfentanyl and Furanylfentanyl. Bilel S, Azevedo Neto J, Arfè R, Tirri M, Gaudio RM, Fantinati A, Bernardi T, Boccuto F, Marchetti B, Corli G, Ser...

Cannabis-Pionier Bedrocan warnt vor negativen Folgen nach der Legalisie

27. März 2022 | Cannabis als Medizin

Cannabis-Pionier Bedrocan warnt vor negativen Folgen nach der Legalisierung Cannabis könnte in Deutschland legalisiert werden. Doch Europas größter Produzent warnt: Mit der Legalisierung könnte medizinisches Cannabis knapp werden. (Handelsb...

USA. FDA, DEA Pushed to Make Gabapentin a Controlled Substance to Stop 'Widespread Misuse'

26. März 2022 | Gabapentinoide

USA. FDA, DEA Pushed to Make Gabapentin a Controlled Substance to Stop 'Widespread Misuse' In a bid to stop abuse and diversion of the anticonvulsant gabapentin, a watchdog group is petitioning federal regulators to make the drug a controlled sub...

DAZ-Fresh-up – was Apotheker wissen müssen: 5 Jahre Medizinisches Cannabis auf Rezept – die wichtigsten Fragen und Antworten

26. März 2022 | Cannabis als Medizin

DAZ-Fresh-up – was Apotheker wissen müssen: 5 Jahre Medizinisches Cannabis auf Rezept – die wichtigsten Fragen und Antworten Seit dem Inkrafttreten des sogenannten „Cannabisgesetzes“ am 10. März 2017 können Ärzt:innen Patient:innen mit schw...

Warnmeldung: Hochpotente synthetische Opioide im Umlauf, z.T. enthalten in gefälschten Medikamenten

12. März 2022 | Opioide

Warnmeldung: Hochpotente synthetische Opioide im Umlauf, z.T. enthalten in gefälschten Medikamenten Aus Deutschland liegen Berichte zu mindestens drei Todesfällen vor, bei denen der Verdacht auf eine (Misch-)Intoxikation mit synthetischen Opioide...

Oxytocin, a Novel Treatment for Methamphetamine Use Disorder.

09. März 2022 | Amphetamine

Oxytocin, a Novel Treatment for Methamphetamine Use Disorder. Edinoff AN, Thompson E, Merriman CE, Alvarez MR, Alpaugh ES, Cornett EM, Murnane KS, Kozinn RL, Shah-Bruce M, Kaye AM, Kaye AD. Neurol Int. 2022 Jan 30;14(1):186-198. doi:...

Novel psychoactive substance.

09. März 2022 | Neue Psychoaktive Substanzen

Novel psychoactive substance. Pucci M, Bradberry S, Ford L. Clin Med (Lond). 2021 Jul;21(4):e430-e431. doi: 10.7861/clinmed.Let.21.4.9. PMID: 35192500; PMCID: PMC8313199. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313199/

The prevalence and pattern of cannabis use among patients attending a methadone treatment clinic in Nairobi, Kenya.

09. März 2022 | Cannabis als Rauschmittel

The prevalence and pattern of cannabis use among patients attending a methadone treatment clinic in Nairobi, Kenya. Ngarachu EW, Kiburi SK, Owiti FR, Kangethe R. Subst Abuse Treat Prev Policy. 2022 Feb 15;17(1):12. doi: 10.1186/s1301...

Outcomes After Implementation of a Benzodiazepine-Sparing Alcohol Withdrawal Order Set in an Integrated Health Care System.

09. März 2022 | Benzodiazepine

Outcomes After Implementation of a Benzodiazepine-Sparing Alcohol Withdrawal Order Set in an Integrated Health Care System. Smith JT, Sage M, Szeto H, Myers LC, Lu Y, Martinez A, Kipnis P, Liu VX. JAMA Netw Open. 2022 Feb 1;5(2):e220...

Polysubstance Use Patterns Among High Dose Benzodiazepine Users: A Latent Class Analysis and Differences Between Male and Female Use.

09. März 2022 | Benzodiazepine

Polysubstance Use Patterns Among High Dose Benzodiazepine Users: A Latent Class Analysis and Differences Between Male and Female Use. Zamboni L, Portoghese I, Congiu A, Zandonai T, Casari R, Fusina F, Bertoldi A, Lugoboni F. Front Ps...

LSD zum Frühstück

09. März 2022 | Verschiedene

LSD zum Frühstück Weltweit nehmen immer mehr Menschen winzige Mengen an LSD zu sich, bevor sie sich auf den Weg zur Arbeit machen. Kreativer, konzentrierter, glücklicher – so lautet das Versprechen des »Microdosing«. Was ist dran an der Beha...

Insights on the Impact of Gamma-Hydroxybutyrate (GHB) Abuse.

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09. März 2022 | Fentanyl

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Strukturvertrag Cannabis zwischen der Deutschen Gesellschaft für Schmerzmedizin und der AOK Rheinland/Hamburg

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USA. As fentanyl overdoses rise, so does use of 'party drug' test strips

23. Februar 2022 | Fentanyl

USA. As fentanyl overdoses rise, so does use of 'party drug' test strips (HealthDay)—Potent and poisonous, the synthetic opioid known as fentanyl has infiltrated nearly every corner of the U.S. illegal street drug market, experts warn. In ...

Complicating the Opioid Epidemic: The Many Faces of Fentanyl

23. Februar 2022 | Fentanyl

Complicating the Opioid Epidemic: The Many Faces of Fentanyl Expanded library of known variants, new research efforts aid the fight against fentanyl. (PNNL - Pacific Northwest National Laboratory, USA, 10.02.2022) https://www.pnnl.gov/news...

"Chill doch mal!“ - Die sedierte Gesellschaft (Podcast)

23. Februar 2022 | Benzodiazepine

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23. Februar 2022 | Cannabis als Medizin

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23. Februar 2022 | Cannabis als Medizin

Anstieg bei Ausgabe medizinischen Cannabis in Apotheken Berlin – Die Nachfrage nach medizinischem Cannabis in Apotheken in Deutschland ist in den vergangenen zehn Jahren drastisch gestiegen. Waren 2011 lediglich acht Kilogramm an Apotheken gelief...

A review on the forensic toxicology of global drug-facilitated sexual assaults.

08. Februar 2022 | Verschiedene

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08. Februar 2022 | Amphetamine

Shifting Pathways of Stimulant Use Among Individuals With Opioid Use Disorder: A Retrospective Analysis of the Last Thirty Years. Ellis MS, Kasper ZA, Scroggins S. Front Psychiatry. 2021 Dec 20;12:786056. doi: 10.3389/fpsyt.2021.7860...

Shifting Pathways of Stimulant Use Among Individuals With Opioid Use Disorder: A Retrospective Analysis of the Last Thirty Years.

08. Februar 2022 | Kokain

Global, regional, and national consumption of controlled opioids: a cross-sectional study of 214 countries and non-metropolitan territories.

08. Februar 2022 | Opioide

Global, regional, and national consumption of controlled opioids: a cross-sectional study of 214 countries and non-metropolitan territories. Richards GC, Aronson JK, Mahtani KR, Heneghan C. Br J Pain. 2022 Feb;16(1):34-40. doi: 10.11...

Clinical Management of Opioid Withdrawal,

08. Februar 2022 | Opioide

Clinical Management of Opioid Withdrawal, Torres-Lockhart, K., Lu, T. Y., Weimer, M. B., Stein, M. R., and Cunningham, C. O. (2022) Addiction. doi.org/10.1111/add.15818. Abstract https://onlinelibrary.wiley.com/d...

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08. Februar 2022 | Kokain

Intranasal oxytocin may improve odds of abstinence in cocaine-dependent patients: results from a preliminary study Wilfrid Noël Raby, MatthewHeller, Demetrios Milliaressis, C.Jean Choi, Cale Basaraba, Martina Pavlicova, Daniel M.Alschuler, France...

Negative Impact of Amphetamine-Type Stimulant Use on Opioid Agonist Treatment Retention in Ontario, Canada.

08. Februar 2022 | Amphetamine

Negative Impact of Amphetamine-Type Stimulant Use on Opioid Agonist Treatment Retention in Ontario, Canada. Morin KA, Vojtesek F, Acharya S, Marsh DC. Front Psychiatry. 2021 Dec 20;12:782066. doi: 10.3389/fpsyt.2021.782066. PMID: 349...

Interactions Between Opioids and Dextroamphetamine on Locomotor Activity: Influence of an Opioid's Relative Efficacy at the Mu Receptor.

08. Februar 2022 | Amphetamine

Interactions Between Opioids and Dextroamphetamine on Locomotor Activity: Influence of an Opioid's Relative Efficacy at the Mu Receptor. Smith MA, Ballard SL, Ballesteros CF, Bonge SA, Casimir AT, Childs LM, Feinstein MA, Griffith AK, Johan...

Significant toxicity following an increase in poisonings with designer benzodiazepines in the Netherlands between 2010 and 2020.

08. Februar 2022 | Benzodiazepine

Significant toxicity following an increase in poisonings with designer benzodiazepines in the Netherlands between 2010 and 2020. Essink S, Nugteren-van Lonkhuyzen JJ, van Riel AJHP, Dekker D, Hondebrink L. Drug Alcohol Depend. 2022 F...

Pregabalin abuse and dependence during insomnia and protocol for short-term withdrawal management with diazepam: examples from case reports.

08. Februar 2022 | Gabapentinoide

Pregabalin abuse and dependence during insomnia and protocol for short-term withdrawal management with diazepam: examples from case reports. Papanna B, Lazzari C, Kulkarni K, Perumal S, Nusair A. Sleep Sci. 2021 Apr-Jun;14(Spec 2):19...

Chronic Pregabalin Abuse with Subacute Encephalopathy Mimicking Autoimmune Encephalitis.

08. Februar 2022 | Gabapentinoide

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08. Februar 2022 | Verschiedene

A systematic literature review of clinical trials and therapeutic applications of ibogaine. Köck P, Frölich K, Walter M, Lang U, Dürsteler KM. J Subst Abuse Treat. 2021 Dec 30:108717. doi: 10.1016/j.jsat.2021.108717. Epub ahead of pr...

Effect of sustained high buprenorphine plasma concentrations on fentanyl-induced respiratory depression: A placebo-controlled crossover study in healthy volunteers and opioid-tolerant patients.

08. Februar 2022 | Fentanyl

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The cocaine-e-cigarette – A theoretical concept of a harm reduction device for current users of smokable cocaine forms.

02. Februar 2022 | Kokain

The cocaine-e-cigarette – A theoretical concept of a harm reduction device for current users of smokable cocaine forms. Steinmetz FP, Stöver H. Drug Science, Policy and Law. January 2021. doi:10.1177/20503245211049310 https://journals.sag...

Clinical management of cannabis withdrawal.

02. Februar 2022 | Cannabis als Rauschmittel

Clinical management of cannabis withdrawal. Connor, JP, Stjepanović, D, Budney, AJ, Le Foll, B, Hall, WD. Addiction. 2022; 1– 21. doi.org/10.1111/add.15743 https://onlinelibrary.wiley.com/doi/full/10.1111/add.15743

Adjunctive Ketamine With Relapse Prevention-Based Psychological Therapy in the Treatment of Alcohol Use Disorder.

02. Februar 2022 | Verschiedene

Adjunctive Ketamine With Relapse Prevention-Based Psychological Therapy in the Treatment of Alcohol Use Disorder. Grabski M, McAndrew A, Lawn W, Marsh B, Raymen L, Stevens T, Hardy L, Warren F, Bloomfield M, Borissova A, Maschauer E, Broomb...

Ketamin hilft Alkoholikern bei der Abstinenz

02. Februar 2022 | Verschiedene

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Psilocybin targets a common molecular mechanism for cognitive impairment and increased craving in alcoholism.

02. Februar 2022 | Verschiedene

Psilocybin targets a common molecular mechanism for cognitive impairment and increased craving in alcoholism. Meinhardt MW, Pfarr S, Fouquet G, Rohleder C, Meinhardt ML, Barroso-Flores J, Hoffmann R, Jeanblanc J, Paul E, Wagner K, Hansson A...

Wie die Droge Psilocybin Alkoholabhängigen zur Abstinenz verhelfen könnte

02. Februar 2022 | Verschiedene

Wie die Droge Psilocybin Alkoholabhängigen zur Abstinenz verhelfen könnte Mannheim – Das Pilzhalluzinogen Psilocybin, das in klinischen Studien bereits erfolgreich zur Behandlung von Depressionen erprobt wurde, könnte Menschen mit einer Alkohola...

Webinar. Aktuelle Forschungsergebnisse und praxisorientierte Informationen zur Verschreibung von Medizinischem Cannabis (Onlinefortbildung am Mittwoch, den 6. April 2022 von 16.00 bis 19.30 Uhr)

02. Februar 2022 | Cannabis als Medizin

Webinar. Aktuelle Forschungsergebnisse und praxisorientierte Informationen zur Verschreibung von Medizinischem Cannabis (Onlinefortbildung am Mittwoch, den 6. April 2022 von 16.00 bis 19.30 Uhr) Dieser Kurs beinhaltet die Vorstellung von aktuelle...

Cannabidiol as Adjunctive Treatment for Opioid Use Disorder

02. Februar 2022 | Cannabis als Medizin

Cannabidiol as Adjunctive Treatment for Opioid Use Disorder This research aims to determine the effects and safety of cannabidiol (CBD) as an adjunctive therapy for patients, who have Opioid Use Disorder and are taking buprenorphine + naloxone. B...

Medical Cannabis Used as an Alternative Treatment for Chronic Pain Demonstrates Reduction in Chronic Opioid Use - A Prospective Study.

02. Februar 2022 | Cannabis als Medizin

Medical Cannabis Used as an Alternative Treatment for Chronic Pain Demonstrates Reduction in Chronic Opioid Use - A Prospective Study. Benedict G, Sabbagh A, Conermann T. Pain Physician. 2022 Jan;25(1):E113-E119. PMID: 35051158. htt...

USA. New Opioids Called Nitazenes May Be 20 Times Stronger Than Fentanyl

17. Januar 2022 | Opioide

USA. New Opioids Called Nitazenes May Be 20 Times Stronger Than Fentanyl A potent synthetic opioid class called nitazenes has been discovered after people overdosed on them. The nitazene class of medication was created over 60 years ago as a pot...

Etazene induces developmental toxicity in vivo Danio rerio and in silico studies of new synthetic opioid derivative.

17. Januar 2022 | Opioide

Etazene induces developmental toxicity in vivo Danio rerio and in silico studies of new synthetic opioid derivative. Kurach Ł, Chłopaś-Konowałek A, Budzyńska B, Zawadzki M, Szpot P, Boguszewska-Czubara A. Sci Rep. 2021 Dec 20;11(1):2...

Moderater Alkoholkonsum verlängert das Leben (doch) nicht

17. Januar 2022 | Alkohol

Moderater Alkoholkonsum verlängert das Leben (doch) nicht Greifswald – Moderater Alkoholkonsum ist nicht gesundheitsförderlich. Anderslautende Schlussfolgerungen aus der Vergangenheit sind wahrscheinlich auf methodische Mängel in den zugrundelieg...

Sleep Quality Improvements After MDMA-Assisted Psychotherapy for the Treatment of Posttraumatic Stress Disorder.

17. Januar 2022 | Amphetamine

Sleep Quality Improvements After MDMA-Assisted Psychotherapy for the Treatment of Posttraumatic Stress Disorder. Ponte L, Jerome L, Hamilton S, Mithoefer MC, Yazar-Klosinski BB, Vermetten E, Feduccia AA. J Trauma Stress. 2021 Aug;34(...

Kanada. CCENDU Bulletin: Risks and Harms Associated with Nonmedical Benzodiazepines in the Unregulated Drug Supply in Canada

17. Januar 2022 | Benzodiazepine

Kanada. CCENDU Bulletin: Risks and Harms Associated with Nonmedical Benzodiazepines in the Unregulated Drug Supply in Canada This bulletin summarizes the risks and harms associated with nonmedical benzodiazepines and benzodiazepine-like substance...

Cannabis and Psychosis: Recent Epidemiological Findings Continuing the “Causality Debate”

17. Januar 2022 | Cannabis als Rauschmittel

Cannabis and Psychosis: Recent Epidemiological Findings Continuing the “Causality Debate” Suhas Ganesh and Deepak Cyril D’Souza American Journal of Psychiatry 2022 179:1, 8-10 https://ajp.psychiatryonline.org/doi/...

Transcranial Magnetic Stimulation for the Treatment of Cocaine Addiction: A Systematic Review.

17. Januar 2022 | Kokain

Transcranial Magnetic Stimulation for the Treatment of Cocaine Addiction: A Systematic Review. Torres-Castaño A, Rivero-Santana A, Perestelo-Pérez L, Duarte-Díaz A, Toledo-Chávarri A, Ramos-García V, Álvarez-Pérez Y, Cudeiro-Mazaira J, Padr...

Ibrutinib as a potential therapeutic for cocaine use disorder.

17. Januar 2022 | Kokain

Ibrutinib as a potential therapeutic for cocaine use disorder. Huggett SB, Hatfield JS, Walters JD, McGeary JE, Welsh JW, Mackay TFC, Anholt RRH, Palmer RHC. Transl Psychiatry. 2021 Dec 8;11(1):623. doi: 10.1038/s41398-021-01737-5. P...

Ayahuasca Technical Report

17. Januar 2022 | Verschiedene

Ayahuasca Technical Report 26 pages with all the latest research-based facts about ayahuasca, its uses, pharmacology, legal status and therapeutic effects, signed by 11 world-class experts and researchers. The 2021 Ayahuasca Technical Report and...

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