| Hans-Günter Meyer-Thompson | Buprenorphin
RBP-6000: a rationally designed prolonged-release buprenorphine formulation
RBP-6000: a rationally designed prolonged-release buprenorphine formulation
Authors: Wiest K., Shaya G., Somaini L., and Greenwald M.
Summary: Background. RBP-6000 (Sublocade®; Subutex Prolonged Release Solution for Injection®) is a monthly prolonged-release subcutaneous formulation of buprenorphine that has been rationally designed to achieve sustained mu-opioid receptor (MOR) occupancy at levels that suppress withdrawal symptoms, drug-liking and craving, which drive addiction
Heroin Addiction and Related Clinical Problems, Published Ahead of Print, January 18, 2021
https://www.heroinaddictionrelatedclinicalproblems.org/download-article.php?idarticolodoi=Adoi0000310