Poisoning Deaths Associated With Buprenorphine Almost Always Involve Sedatives or Other Opioids
Poisoning Deaths Associated With Buprenorphine Almost Always Involve Sedatives or Other Opioids
Buprenorphine has a favorable safety profile because of its partial agonist and ceiling respiratory depression effects. However, there are poisoning deaths associated with it. Researchers used data from autopsies of sudden and unexpected deaths in Finland, which has high rates of illicit buprenorphine use, to investigate the extent to which these deaths were associated with the use of other substances. In Finland, all sudden and unexpected deaths (12% of all deaths in this study period) are investigated with autopsy, including comprehensive toxicology in 75%. (Alcohol, Other Drugs, and Health: Current Evidence, USA, März-April 2021)
http://www.bu.edu/aodhealth/2021/04/29/poisoning-deaths-associated-with-buprenorphine-almost-always-involve-sedatives-or-other-opioids/