Gabapentinoids increase the potency of fentanyl and heroin and decrease the potency of naloxone to antagonize fentanyl and heroin in rats discriminating fentanyl. 

Gabapentinoids increase the potency of fentanyl and heroin and decrease the potency of naloxone to antagonize fentanyl and heroin in rats discriminating fentanyl. 

Hiranita T, Flynn SM, Grisham AK, Mijares AE, Murphy EN, France CP. 

J Pharmacol Exp Ther. 2024 Aug 23:JPET-AR-2024-002323. doi: 10.1124/jpet.124.002323. Epub ahead of print. PMID: 39179416.

https://jpet.aspetjournals.org/content/jpet/early/2024/08/23/jpet.124.002323.full.pdf