Prescription opioids and longitudinal changes in cognitive function in older adults: A population-based observational study. Warner, NS, Hanson, AC, Schulte, PJ, Habermann, EB, Warner, DO, Mielke, MM.  J Am Geriatr ...

Israel. Earliest evidence of opium use found in burial site in Israel Evidence of the earliest use of the narcotic opium has been found in an ancient burial site in Israel. Traces were discovered by archaeologists in pottery vessels at the compl...

Could Opium Gum be the Solution to the Overdose Crisis? The prohibitionist regime surrounding the adult use of drugs has had devastating impacts on individuals, communities, and entire regions, spurring corruption, deteriorating the rule of law, ...

Dynamic recognition of naloxone, morphine and endomorphin1 in the same pocket of µ-opioid receptors.  Zhang X, Sun MY, Zhang X, Guo CR, Lei YT, Wang WH, Fan YZ, Cao P, Li CZ, Wang R, Li XH, Yu Y, Yang XN.  Front Mol Biosci. 2022 Aug 16...

Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking.  Maza, N., Wang, D., Kowalski, C. et al. Nat Neurosci (2022). doi.org/10.1038/s41593-022-01135-0 https://www.nature.com/art...

Characterizing the Experience of Tapentadol Nonmedical Use: Mixed Methods Study.  Vosburg SK, Dailey-Govoni T, Beaumont J, Butler SF, Green JL.  JMIR Form Res. 2022 Jun 10;6(6):e16996. doi: 10.2196/16996. PMID: 35687397; PMCID: PM...